Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 454, 589-590 (31 July 2008) | doi:10.1038/454589a; Published online 30 July 2008
Open Innovation Challenges
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
- More Challenges
- Powered by:
nature jobs
Academic Surgical Pathologists GI / Breast / GYN
- Medical College of Wisconsin
- Milwaukee, Wisconsin, USA
Postdoctoral Position Studying Immunology
- The University of Chicago
- Chicago, IL
Behavioural neuroscience: The circuit of fear
Pankaj Sah1 & R. Frederick Westbrook2
Abstract
Do you find it difficult to overcome an irrational fear? Blame it on the specific neural circuits hardwired in the brain that control fear recognition, and fear renewal even when fear has seemingly been overcome.
Learning to predict danger allows animals to defend themselves against harm and is crucial for survival. The neural mechanisms that subserve these functions are evolutionarily old, and their dysfunction is thought to underlie a host of anxiety disorders in humans, including post-traumatic stress and panic disorder1.
- Pankaj Sah is at the Queensland Brain Institute, University of Queensland, St Lucia, Queensland 4072, Australia.
Email: pankaj.sah@uq.edu.au - R. Frederick Westbrook is in the School of Psychology, University of New South Wales, Sydney, New South Wales 2052, Australia.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Switching on and off fear by distinct neuronal circuitsNature Article (31 Jul 2008)
Neurons in medial prefrontal cortex signal memory for fear extinctionNature Letters to Editor (07 Nov 2002)
Human orbitofrontal cortex mediates extinction learning while accessing conditioned representations of valueNature Neuroscience Article (01 Oct 2004)
See all 26 matches for Research