Abstract
Replying to: Frank, C. G., Sanyal, S., Rush, J. S., Waechter C. J. & Menon A. K. Nature 454, 10.1038/nature07165 (2008)
The controlled translocation of polar phospholipid head groups between the two leaflets of biological membranes is thought to be meditated by proteins called flippases. Several candidate polyisoprene phosphate–oligosaccharide flippases have been described1,2,3, including Rft1 for Dol-PP-GlcNAc2Man5 by us4 and now questioned by Frank et al.5.
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Helenius, J., Ng, D., Marolda, C. et al. Helenius et al. reply. Nature 454, E4–E5 (2008). https://doi.org/10.1038/nature07164
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DOI: https://doi.org/10.1038/nature07164
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