Tracking arsenic from the Himalayas to southeast Asia's water supply.
doi:10.1038/7203xa
Table of contents
Volume 454 Number 7203 pp367-550
(this content only available online) indicates content that is available online only
Making the paper: Scott Fendorf px
Abstractions px
doi:10.1038/7203xb
From the blogosphere px
doi:10.1038/7203xc
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Editorials
China: China's challenges p367
By almost every measure, China's growth is extraordinary. But behind the astonishing statistics is a more complex reality.
doi:10.1038/454367a
Mind the gaps p368
The incoming US administration can and should reverse the neglect of Earth observations.
doi:10.1038/454368a
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Research Highlights
Zoology: Bird's-nose view p370
doi:10.1038/454370a
Physics: Parting a cloud p370
doi:10.1038/454370b
Acoustics: Chuckle vision p370
doi:10.1038/454370c
Plant sciences: Poisonous grains p370
doi:10.1038/454370d
Physics: Gravity up close p370
doi:10.1038/454370e
Neuroscience: Location, location, location p371
doi:10.1038/454371a
Astronomy: Bright origins p371
doi:10.1038/454371b
Infectious disease: DARC matters p371
doi:10.1038/454371c
Chemistry: Easy bonding p371
doi:10.1038/454371d
Molecular biology: WHAMM! p371
doi:10.1038/454371e
Genetics: DNA potholes p371
doi:10.1038/454371f
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News
Oil cost hits ship studies p372
International Polar Year is feeling the pinch.
Quirin Schiermeier
doi:10.1038/454372a
Spinal cord revealed in free gene map p373
Allen Institute for Brain Science releases first data set.
Meredith Wadman
doi:10.1038/454373a
Think tank reveals plan to manage tropical forests p373
Novel way to use carbon credits to save trees.
Jeff Tollefson
doi:10.1038/454373b
China: Where have all the flowers gone? p374
At least 117 boys were being born for every 100 girls at the beginning of this century in China.
Phillip Ball
doi:10.1038/454374a
Snapshot: Track record p377
Chinese scientist takes turn with Olympic torch.
David Cyranoski
doi:10.1038/454377a
Affymetrix in new patents row p377
MIT files suit over GeneChip technology.
Heidi Ledford
doi:10.1038/454377b
Coral isotopes show quake history p378
Eric Hand
doi:10.1038/454378a
Fusion verdict: misconduct p379
Eugenie Samuel Reich
doi:10.1038/454379a
Fusion verdict: misconduct p379
Eugenie Samuel Reich
doi:10.1038/454379a
Sidelines p379
doi:10.1038/454379b
Roche bids for remaining Genentech stake p381
doi:10.1038/454381a
German public–private partnership breaks ground p381
doi:10.1038/454381b
Clinical trialists less likely to seek grant renewals p381
doi:10.1038/454381c
Google Books expands its non-English resources p381
doi:10.1038/454381d
US Senate approves $48 billion global AIDS funding p381
doi:10.1038/454381e
Ontario acts to protect its boreal forests p381
doi:10.1038/454381f
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News Features
China: The great contender p382
Chin'as performance has been remarkable in any number of fields. Declan Butler charts the country's scientific and economic growth.
doi:10.1038/454382a
China: Visions of China p384
Can the Chinese government meet its ambitious targets on space, the environment, research, energy and health? David Cyranoski takes a look at China today and what it hopes to be tomorrow.
doi:10.1038/454384a
China: Stoking the fire p388
China burns more coal than any other country; how it does so in the future will determine our planet's climate. Jeff Tollefson reports from Beijing.
Jeff Tollefson
doi:10.1038/454388a
China: The third pole p393
Climate change is coming fast and furious to the Tibetan plateau. Jane Qiu reports on the changes atop the roof of the world.
doi:10.1038/454393a
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Correspondence
China's move to higher-meat diet hits water security p397
Junguo Liu, Hong Yang & H. H. G. Savenije
doi:10.1038/454397a
In the wake of two retractions, a request for investigation p397
Homme W. Hellinga
doi:10.1038/454397b
Fusion needs a realistic cost assessment p397
J. H. Evans
doi:10.1038/454397c
Fewer academics are not the answer to funding woes p397
Philip Strange
doi:10.1038/454397d
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Commentaries
China: The prizes and pitfalls of progress p398
Pushes to globalize science must not threaten local innovations in developing countries, argues Lan Xue.
Lan Xue
doi:10.1038/454398a
China: In their words p399
Researchers and businesspeople in China, expatriates and 'returnees' give their views of what it will take to make China a research and innovation powerhouse.
doi:10.1038/454399a
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Books and Arts
China: How one child was deemed enough p403
Scientific policy-making in China has come a long way since the 1970s, argue Ling Chen and Gang Zhang.
doi:10.1038/454403a
China: A museum in every district p404
China: A shared view of the heavens p405
A woodcut of Ferdinand Verbiest, the Kangxi Emperor's Flemish astronomer and mastermind of Beijing's Ancient Observatory, records a remarkable seventeenth-century cultural exchange. Martin Kemp explains.
Martin Kemp
doi:10.1038/454405a
Core caper p406
doi:10.1038/454406a
Geological history turned upside down p406
doi:10.1038/454406b
Romance among robots p407
doi:10.1038/454407a
Doctorate gets a lesson in management p408
doi:10.1038/454408a
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Essays
China: The man who unveiled China p409
An English biochemist single-handedly changed the West's perception of China, revealing its past scientific glories and predicting more to come. Simon Winchester investigates the ongoing legacy of Joseph Needham.
Simon Winchester
doi:10.1038/454409a
China: The end of the science superpowers p412
Could the end of US world dominance over research mark the passing of national science giants, ask J. Rogers Hollingsworth, Karl H. Müller and Ellen Jane Hollingsworth.
J. Rogers Hollingsworth, Karl H. Müller & Ellen Jane Hollingsworth
doi:10.1038/454412a
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News and Views
環境科学: 毒入り水の源を探す
Environmental science: Poisoned waters traced to source p415
South Asia's well-water is widely polluted with arsenic, but no one has located the source. A study on the Mekong River finds that contamination begins in pond sediments, and is spread by groundwater flow to wells.
Charles F. Harvey
doi:10.1038/454415a
日本語要約 | Full Text | PDF (316K)
生理学: ミオグロビンの新しい役割
Physiology: Myoglobin's new clothes p416
Nitric oxide generated from the nitrite ion limits the tissue damage caused by restricted blood flow. Gene knockout experiments in mice now reveal that myoglobin is the mediator of this effect.
Andrew Cossins & Michael Berenbrink
doi:10.1038/454416a
日本語要約 | Full Text | PDF (134K)
分子コンピューティング: 論理ゲートの層
Molecular computing: A layer of logic p417
Silicon chips have thousands of electronic logic gates etched on them. But there are other ways to decorate monolithic surfaces with logic gates, as a system using metal complexes secured to glass slides shows.
A. Prasanna de Silva
doi:10.1038/454417a
日本語要約 | Full Text | PDF (639K)
アルツハイマー病: ワクチンに向かう
Alzheimer's disease: Moving towards a vaccine p418
An agent that clears disease-associated amyloid aggregates from the brains of patients with Alzheimer's disease does not alleviate disease progression. Yet this disappointing news should not rule out such potential therapies.
David M. Holtzman
doi:10.1038/454418a
日本語要約 | Full Text | PDF (775K)
50 & 100 Years Ago p419
doi:10.1038/454419a
材料科学: 2つのタイル並べ問題
Materials science: A tale of two tilings p420
What do you get when you cross a crystal with a quasicrystal? The answer is a structure that links the ancient tiles of Archimedes, the iconic Fibonacci sequence of numbers and a book from the seventeenth century.
Sharon C. Glotzer & Aaron S. Keys
doi:10.1038/454420a
日本語要約 | Full Text | PDF (205K)
ゲノミクス: 減数分裂の最先端
Genomics: Thoroughly modern meiosis p421
Meiotic recombination shuffles the genome, so each generation inherits a new combination of parental traits. Combining traditional and modern approaches, new work pinpoints where recombination occurs genome-wide.
Michael Lichten
doi:10.1038/454421a
日本語要約 | Full Text | PDF (123K)
生態学: 森林の空調システム
Ecology: Forest air conditioning p422
During the growing season, with photosynthesis at its peak, leaf temperatures remain constant over a wide latitudinal range. This is a finding that overturns a common assumption and has various ramifications.
F. I. Woodward
doi:10.1038/454422a
日本語要約 | Full Text | PDF (294K)
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Horizons
Life, logic and information p424
Focusing on information flow will help us to understand better how cells and organisms work.
Paul Nurse
doi:10.1038/454424a
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Insight: Inflammation
The role of exercise and PGC1
Insight: Inflammation -
Insight: Inflammation
Inflammation p427
Origin and physiological roles of inflammation p428
Cancer-related inflammation p436
Alberto Mantovani, Paola Allavena, Antonio Sica & Frances Balkwill
doi:10.1038/nature07205
The development of allergic inflammation p445
Stephen J. Galli, Mindy Tsai & Adrian M. Piliponsky
doi:10.1038/nature07204
From endoplasmic-reticulum stress to the inflammatory response p455
The role of exercise and PGC1
in inflammation and chronic disease p463
Integration of metabolism and inflammation by lipid-activated nuclear receptors p470
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Structure of a
Articles
酵母の減数分裂における乗り換えと非乗り換えの高分解能マッピング
High-resolution mapping of meiotic crossovers and non-crossovers in yeast p479
Eugenio Mancera, Richard Bourgon, Alessandro Brozzi, Wolfgang Huber & Lars M. Steinmetz
doi:10.1038/nature07135
Gタンパク質共役型β1アドレナリン受容体の構造
Structure of a 
1-adrenergic G-protein-coupled receptor p486
Tony Warne, Maria J. Serrano-Vega, Jillian G. Baker, Rouslan Moukhametzianov, Patricia C. Edwards, Richard Henderson, Andrew G. W. Leslie, Christopher G. Tate & Gebhard F. X. Schertler
doi:10.1038/nature07101
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Letters
赤外領域で明らかになった、クエーサーの降着円盤に特徴的な青化スペクトル
The characteristic blue spectra of accretion disks in quasars as uncovered in the infrared p492
Makoto Kishimoto, Robert Antonucci, Omer Blaes, Andy Lawrence, Catherine Boisson, Marcus Albrecht & Christian Leipski
doi:10.1038/nature07114
折り曲げ自在なプラスチック基板上の中規模カーボンナノチューブ薄膜集積回路
Medium-scale carbon nanotube thin-film integrated circuits on flexible plastic substrates p495
Qing Cao, Hoon-sik Kim, Ninad Pimparkar, Jaydeep P. Kulkarni, Congjun Wang, Moonsub Shim, Kaushik Roy, Muhammad A. Alam & John A. Rogers
doi:10.1038/nature07110
十角形準結晶表面上のアルキメデス様タイリング
Archimedean-like tiling on decagonal quasicrystalline surfaces p501
Jules Mikhael, Johannes Roth, Laurent Helden & Clemens Bechinger
doi:10.1038/nature07074
アジアの地下水へのヒ素の流出源は地表付近の湿地堆積物である
Near-surface wetland sediments as a source of arsenic release to ground water in Asia p505
Matthew L. Polizzotto, Benjamin D. Kocar, Shawn G. Benner, Michael Sampson & Scott Fendorf
doi:10.1038/nature07093
2008年Wenchuan地震の応力変化と四川盆地の危険の増加
Stress changes from the 2008 Wenchuan earthquake and increased hazard in the Sichuan basin p509
Tom Parsons, Chen Ji & Eric Kirby
doi:10.1038/nature07177
亜熱帯から北方帯までの樹木の葉温にみられる収束
Subtropical to boreal convergence of tree-leaf temperatures p511
Brent R. Helliker & Suzanna L. Richter
doi:10.1038/nature07031
3つの河口域における寄生種と自由生活種の生物体量の生態系エネルギー的な意義
Ecosystem energetic implications of parasite and free-living biomass in three estuaries p515
Armand M. Kuris, Ryan F. Hechinger, Jenny C. Shaw, Kathleen L. Whitney, Leopoldina Aguirre-Macedo, Charlie A. Boch, Andrew P. Dobson, Eleca J. Dunham, Brian L. Fredensborg, Todd C. Huspeni, Julio Lorda, Luzviminda Mababa, Frank T. Mancini, Adrienne B. Mora, Maria Pickering, Nadia L. Talhouk, Mark E. Torchin & Kevin D. Lafferty
doi:10.1038/nature06970
ミツバチにおける新規な性決定経路の進化的発生の証拠
Evidence for the evolutionary nascence of a novel sex determination pathway in honeybees p519
Martin Hasselmann, Tanja Gempe, Morten Schiøtt, Carlos Gustavo Nunes-Silva, Marianne Otte & Martin Beye
doi:10.1038/nature07052
C型肝炎ウイルスRNAの組成依存的RIG-I認識によって誘導される自然免疫
Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA p523
Takeshi Saito, David M. Owen, Fuguo Jiang, Joseph Marcotrigiano & Michael Gale Jr.
doi:10.1038/nature07106
老化した筋幹細胞におけるpSmad3およびNotch間の不均衡はCDK阻害因子を誘発する
Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells p528
Morgan E. Carlson, Michael Hsu & Irina M. Conboy
doi:10.1038/nature07034
日本語要約 | Full Text | PDF (1,461K) | Supplementary information
最終分化したショウジョウバエ感覚ニューロンにおけるロドプシン発現の切り替え
Switch of rhodopsin expression in terminally differentiated Drosophila sensory neurons p533
Simon G. Sprecher & Claude Desplan
doi:10.1038/nature07062
STIM1のオリゴマー形成は小胞体のカルシウム枯渇とCRACチャネル活性化を結びつける
Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation p538
Riina M. Luik, Bin Wang, Murali Prakriya, Minnie M. Wu & Richard S. Lewis
doi:10.1038/nature07065
出芽酵母（Saccharomyces cerevisiae）のATMオルソログは、切断による染色体転座を抑制する
Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations p543
Kihoon Lee, Yu Zhang & Sang Eun Lee
doi:10.1038/nature07054
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Career View
Naturejobs
ProspectProspects p547
National Academies panel endorses professional master's degree.
Gene Russo
doi:10.1038/nj7203-547a
Career View
Brent Reynolds, director of the Adult Stem Cell Engineering and Therapeutic Core, McKnight Brain Center, University of Florida, Gainesville p548
Stem-cell scientist embraces Eastern philosophy — and a return to science.
Paul Smaglik
doi:10.1038/nj7203-548a
Vitae for postgraduate development p548
New organization pledges to fight for postgraduate student issues in Britain.
Virginia Gewin
doi:10.1038/nj7203-548b
An unwelcome intrusion p548
It's not the workload that worries me, it's the reverse culture shock.
Aliza le Roux
doi:10.1038/nj7203-548c
