Structure reveals Ebola virus' strengths and weaknesses.
doi:10.1038/7201xa
Table of contents
Volume 454 Number 7201 pp137-252
(this content only available online) indicates content that is available online only
Making the paper: Erica Ollmann Saphire px
Abstractions px
doi:10.1038/7201xb
From the blogosphere px
doi:10.1038/7201xc
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Editorials
The long war against flu p137
That the H5N1 strain of bird flu has not yet caused a pandemic is no cause for complacency. Preparations for the inevitable must be redoubled to mitigate the potential devastation.
doi:10.1038/454137a
An unnecessary battle p137
Neuroscientists and geneticists don't need to be at loggerheads over the biology of mental disorders.
doi:10.1038/454137b
A social contract p138
Efforts to inform US military policy with insights from the social sciences could be a win–win approach.
doi:10.1038/454138a
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Research Highlights
Climate science: A watery carbon bank p140
doi:10.1038/454140a
Neuroscience: Rewiring the brain p140
doi:10.1038/454140b
Materials: Colourful clay p140
doi:10.1038/454140c
Remote sensing: Rainforest shrinkage p140
doi:10.1038/454140d
Plant biology: An egg-spedient defence p140
doi:10.1038/454140e
Atmospheric chemistry: Forgotten gas p140
doi:10.1038/454140f
Ecology: Competing keeps bees busy p141
doi:10.1038/454141a
Geology: Glacial speeds p141
doi:10.1038/454141b
Evolution: Photosynthetic ancestors p141
doi:10.1038/454141c
Molecular neuroscience: Pores for thought p141
doi:10.1038/454141d
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News
Leaders still vague on emissions targets p142
G8 talks fail to advance fight against climate change.
Olive Heffernan
doi:10.1038/454142a
Researcher battles CNRS reforms p143
Medal winner rallies French scientists.
Declan Butler
doi:10.1038/454143a
Scientists rally to Mexican researchers' plea p143
Dispute threatens to tear physical-sciences institute apart.
Rex Dalton
doi:10.1038/454143b
When there's no room to grow p144
To maintain profits in the face of rising development costs and slow drug pipelines, big pharmaceutical firms are trying to cut back. Heidi Ledford examines how GlaxoSmithKline has tried to adapt.
Heidi Ledford
doi:10.1038/454144a
A Spanish revival p147
Spain's Ministry of Science and Innovation was re-established in April, four years after its dissolution in 2004. Cristina Garmendia, a former molecular biologist and chief executive of the Genetrix group of biotech companies, heads the new ministry.
Cristina Jimenez
doi:10.1038/454147a
Sidelines p147
Scribbles on the margins of science.
doi:10.1038/454147b
Shock tactics point to risk after quake p148
Geologists aim to provide daily hazard maps.
Quirin Schiermeier
doi:10.1038/454148a
Super-sensitive tool key to dark-matter claim p148
Theorists unlock mysteries of experimental results.
Geoff Brumfiel
doi:10.1038/454148b
Boyz 2 pipettemen p149
Lab equipment gets the X factor.
Brendan Maher
doi:10.1038/454149a
Australian panel lays plans for emissions trading p150
doi:10.1038/454150a
UK physicists discover full scope of budget cuts p150
doi:10.1038/454150b
India takes pole position to study climate change p150
doi:10.1038/454150c
Training for human studies may become mandatory p150
doi:10.1038/454150d
Texas educator sues over job loss and creationism p150
doi:10.1038/454150e
Iranians face nuclear-study ban in the Netherlands p150
doi:10.1038/454150f
NPG Archiving for authors p150
doi:10.1038/454150g
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News Features
Archaeology: The lost world p151
Armed with a map depicting a 10,000-year-old landscape submerged beneath the North Sea and fresh evidence from nearby sites, archaeologists are realizing that early humans were more territorial than was previously thought. Laura Spinney reports.
doi:10.1038/454151a
Psychiatric genetics: The brains of the family p154
Does the difficulty in finding the genes responsible for mental illness reflect the complexity of the genetics or the poor definitions of psychiatric disorders? Alison Abbott reports.
doi:10.1038/454154a
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Correspondence
International law should govern release of GM mosquitoes p158
Future of open access could be online and peer-reviewed p158
Genetic testing must recognize impact of bad news on recipient p158
Action needed to prevent extinctions caused by disease p159
Cuddly animals don't persuade poor people to back conservation p159
Correction p159
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Commentaries
The contents of the syringe p160
The influenza vaccine failed this winter. Steven Salzberg suggests that future success relies on sharing data more widely and making the virus strain selection process more transparent.
Steven Salzberg
doi:10.1038/454160a
Ready for avian flu? p162
Committing to a vaccine stockpile is just the beginning. Tadataka Yamada, Alice Dautry and Mark Walport offer a roadmap for heading off a global avian influenza catastrophe.
Tadataka Yamada, Alice Dautry & Mark Walport
doi:10.1038/454162a
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Books and Arts
Testing times for genomics p163
In a bid to popularize the science and ethics of human genetics, two new books fail to address developments in gene testing since completion of the Human Genome Project, says Kathy Hudson.
doi:10.1038/454163a
The cost of vague patents p164
doi:10.1038/454164a
A new window on the Victorians p165
doi:10.1038/454165a
Culture dish p166
doi:10.1038/454166a
The leaning tower of Perth p166
doi:10.1038/454166b
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Essay
Behind the looking-glass p167
To understand how mirror neurons help to interpret actions, we must delve into the networks in which these cells sit, say Antonio Damasio and Kaspar Meyer.
Antonio Damasio & Kaspar Meyer
doi:10.1038/454167a
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News and Views
古生物学: カレイの化石の目はどこに？
Palaeontology: Squint of the fossil flatfish p169
Evolutionary biologists have floundered when trying to explain how the asymmetrical head of flatfishes came about. 'Gradually' is the answer arising from exquisite studies of 45-million-year-old fossil specimens.
Philippe Janvier
doi:10.1038/454169a
日本語要約 | Full Text | PDF (755K)
惑星科学: 出来立ての月は水が豊富だった
Planetary science: The early Moon was rich in water p170
Analyses of lunar volcanic glasses show that they are rich in volatile elements and water. If parts of the lunar mantle contain as much water as Earth's, does this imply that the water has a common origin?
Marc Chaussidon
doi:10.1038/454170a
50 & 100 Years Ago p171
doi:10.1038/454171a
がん: 予想外の依存性
Cancer: An unexpected addiction p172
Both oncogenes and normal genes can mediate the development and progress of cancer. What used to separate their effects was cancer's dependence on, or 'addiction' to, oncogenes but not normal genes. Not any more.
John D. Shaughnessy
doi:10.1038/454172a
日本語要約 | Full Text | PDF (401K)
小惑星: 空飛ぶ円盤の作り方
Asteroids: How to make a flying saucer p173
Wherever we look in the Solar System, small bodies often seem to come in twos. Simulations show how asteroids spun in the Sun can produce such pairings — one of whose members acquires a strangely familiar shape.
William F. Bottke
doi:10.1038/454173a
日本語要約 | Full Text | PDF (223K)
固体化学: 臭化リチウムの新しい配列
Solid-state chemistry: New order for lithium bromide p174
It's all very well predicting which forms of crystal an inorganic solid can adopt, but how can proof be obtained if these structures aren't thermodynamically stable? The answer is to build them up atom by atom.
David C. Johnson
doi:10.1038/454174a
日本語要約 | Full Text | PDF (343K)
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Brief Communications Arising
Do female hyaenas choose mates based on tenure? pE1
Russell C. Van Horn, Heather E. Watts & Kay E. Holekamp
doi:10.1038/nature07122
Höner et al. reply pE2
Oliver P. Höner, Bettina Wachter, Marion L. East, W. Jürgen Streich, Kerstin Wilhelm, Terry Burke & Heribert Hofer
doi:10.1038/nature07123
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Articles
エボラウイルス感染の生存者由来の抗体と結合したエボラウイルス糖タンパク質の構造
Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor p177
Jeffrey E. Lee, Marnie L. Fusco, Ann J. Hessell, Wendelien B. Oswald, Dennis R. Burton & Erica Ollmann Saphire
doi:10.1038/nature07082
日本語要約 | Full Text | PDF (1,075K) | Supplementary information
Gタンパク質共役型受容体オプシンのリガンド非結合状態の結晶構造
Crystal structure of the ligand-free G-protein-coupled receptor opsin p183
Jung Hee Park, Patrick Scheerer, Klaus Peter Hofmann, Hui-Woog Choe & Oliver Peter Ernst
doi:10.1038/nature07063
日本語要約 | Full Text | PDF (2,223K) | Supplementary information
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Letters
連星系をなす小型小惑星の起源は自転による破壊である
Rotational breakup as the origin of small binary asteroids p188
Kevin J. Walsh, Derek C. Richardson & Patrick Michel
doi:10.1038/nature07078
日本語要約 | Full Text | PDF (481K)
月の火山ガラスに残された揮発性成分と月内部の水の存在
Volatile content of lunar volcanic glasses and the presence of water in the Moon's interior p192
Alberto E. Saal, Erik H. Hauri, Mauro L. Cascio, James A. Van Orman, Malcolm C. Rutherford & Reid F. Cooper
doi:10.1038/nature07047
ボルマン分光法で明らかになった四重極子遷移
Quadrupole transitions revealed by Borrmann spectroscopy p196
Robert F. Pettifer, Stephen P. Collins & David Laundy
doi:10.1038/nature07099
アンダードープ高Tc超伝導体の渦糸状態における多成分フェルミ面
A multi-component Fermi surface in the vortex state of an underdoped high-Tc superconductor p200
Suchitra E. Sebastian, N. Harrison, E. Palm, T. P. Murphy, C. H. Mielke, Ruixing Liang, D. A. Bonn, W. N. Hardy & G. G. Lonzarich
doi:10.1038/nature07095
パークフィールドSAFOD掘削点における人工震源測定で得られた地震前速度変化
Preseismic velocity changes observed from active source monitoring at the Parkfield SAFOD drill site p204
Fenglin Niu, Paul G. Silver, Thomas M. Daley, Xin Cheng & Ernest L. Majer
doi:10.1038/nature07111
日本語要約 | Full Text | PDF (688K)
カレイ目魚類の左右非対称性の進化的起源
The evolutionary origin of flatfish asymmetry p209
社会的多様性は公共財ゲームでの協力行動の出現を促進する
Social diversity promotes the emergence of cooperation in public goods games p213
Francisco C. Santos, Marta D. Santos & Jorge M. Pacheco
doi:10.1038/nature06940
日本語要約 | Full Text | PDF (1,962K) | Supplementary information
ショウジョウバエで温度選択性を制御する内在温度センサー
An internal thermal sensor controlling temperature preference in Drosophila p217
Fumika N. Hamada, Mark Rosenzweig, Kyeongjin Kang, Stefan R. Pulver, Alfredo Ghezzi, Timothy J. Jegla & Paul A. Garrity
doi:10.1038/nature07001
破骨細胞の大きさは、LIF/LIF受容体シグナル伝達と低酸素状態を介してFra-2によって制御される
Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia p221
Aline Bozec, Latifa Bakiri, Astrid Hoebertz, Robert Eferl, Arndt F. Schilling, Vukoslav Komnenovic, Harald Scheuch, Matthias Priemel, Colin L. Stewart, Michael Amling & Erwin F. Wagner
doi:10.1038/nature07019
多発性骨髄腫におけるIRF4依存
IRF4 addiction in multiple myeloma p226
Arthur L. Shaffer, N. C. Tolga Emre, Laurence Lamy, Vu N. Ngo, George Wright, Wenming Xiao, John Powell, Sandeep Dave, Xin Yu, Hong Zhao, Yuxin Zeng, Bangzheng Chen, Joshua Epstein & Louis M. Staudt
doi:10.1038/nature07064
赤血球系細胞のオートファジー性成熟におけるNixの不可欠な役割
Essential role for Nix in autophagic maturation of erythroid cells p232
Hector Sandoval, Perumal Thiagarajan, Swapan K. Dasgupta, Armin Schumacher, Josef T. Prchal, Min Chen & Jin Wang
doi:10.1038/nature07006
生きた細胞中での個々のHIV-1ウイルス粒子の生成の画像化
Imaging the biogenesis of individual HIV-1 virions in live cells p236
Nolwenn Jouvenet, Paul D. Bieniasz & Sanford M. Simon
doi:10.1038/nature06998
Mei-P26はショウジョウバエ卵巣幹細胞系列のマイクロRNAと細胞増殖を制御する
Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage p241
Ralph A. Neumüller, Joerg Betschinger, Anja Fischer, Natascha Bushati, Ingrid Poernbacher, Karl Mechtler, Stephen M. Cohen & Juergen A. Knoblich
doi:10.1038/nature07014
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Corrigenda
Neurophysiology: Sensing temperature without ion channels p246
An extremely luminous X-ray outburst at the birth of a supernova p246
A. M. Soderberg, E. Berger, K. L. Page, P. Schady, J. Parrent, D. Pooley, X.-Y. Wang, E. O. Ofek, A. Cucchiara, A. Rau, E. Waxman, J. D. Simon, D. C.-J. Bock, P. A. Milne, M. J. Page, J. C. Barentine, S. D. Barthelmy, A. P. Beardmore, M. F. Bietenholz, P. Brown, A. Burrows, D. N. Burrows, G. Bryngelson, S. B. Cenko, P. Chandra, J. R. Cummings, D. B. Fox, A. Gal-Yam, N. Gehrels, S. Immler, M. Kasliwal, A. K. H. Kong, H. A. Krimm, S. R. Kulkarni, T. J. Maccarone, P. Mészáros, E. Nakar, P. T. O'Brien, R. A. Overzier, M. de Pasquale, J. Racusin, N. Rea & D. G. York
doi:10.1038/nature07134
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Region
Career View
Highlights
Naturejobs
ProspectProspects p247
Naturejobs' 'Source Event' activities aim to provide sage careers advice online and in person.
Gene Russo
doi:10.1038/nj7201-247a
Region
Catalonian powerhouse p248
Spain is revitalizing its science base, with Barcelona surging ahead as a Mediterranean science hub, reports Quirin Schiermeier.
Quirin Schiermeier
doi:10.1038/nj7201-248a
Career View
James Ryan, founding dean, Joint School of Nanoscience and Nanoengineering, North Carolina A&T State University and the University of North Carolina at Greensboro p250
Nanoscientist aims to set up a major nanotechnology centre.
Virginia Gewin
doi:10.1038/nj7201-250a
Top states vie to fund more science p250
Major life-science initiatives in Massachusetts and Maryland should mean thousands of science-related jobs.
Paul Smaglik
doi:10.1038/nj7201-250b
I'll take one 'eureka' please p250
Looking for that eureka moment.
Zachary Lippman
doi:10.1038/nj7201-250c
Highlights
Highlight: Spain
doi:10.1038/nj0219
