Unusual brain receptors weaken resistance to cocaine cravings.
doi:10.1038/7200xia
Table of contents
Volume 454 Number 7200 pp1-136
(this content only available online) indicates content that is available online only
Making the paper: Marina Wolf pxi
Abstractions pxi
doi:10.1038/7200xib
From the blogosphere pxi
doi:10.1038/7200xic
Top of page
Editorials
Feasting and fasting p1
Bad nutrition needs the world's attention. Not least that of biologists.
doi:10.1038/454001a
In rude health p1
A treasure-trove of data in the UK National Health Service is set to energize biomedical research.
doi:10.1038/454001b
Does the past have a future in Berlin? p2
Not unless a research institution's managers recognize its value.
doi:10.1038/454002a
Top of page
Research Highlights
Natural history: Nasty, brutish and short p4
doi:10.1038/454004a
Neuroscience: Predicting psychosis p4
doi:10.1038/454004b
Genetics: The genetics of anarchy p4
doi:10.1038/454004c
Chemistry: Flipping brilliant p4
doi:10.1038/454004d
Chemical biology: Anti-Alzheimer's agent p4
doi:10.1038/454004e
Materials science: The heart of glass p4
doi:10.1038/454004f
Genetics: Sex and the cortex p5
doi:10.1038/454005a
Ecology: Drought and the lion p5
doi:10.1038/454005b
Acoustics: Fiddling the numbers p5
doi:10.1038/454005c
Nanotechnology: Electron windmills p5
doi:10.1038/454005d
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News
Neuroscientist: my data published without authorization are 'misleading' p6
Max Planck researchers charged with misusing data.
Alison Abbott
doi:10.1038/454006a
Turkish politics blamed for board block p6
Geologist claims personal views led to job denial.
Geoff Brumfiel
doi:10.1038/454006b
Closer than ever to the Sun p7
Astronomers plan successor for Ulysses spacecraft.
Eric Hand
doi:10.1038/454007a
Reincarnation can save Schrödinger's cat p8
Physicists reverse quantum膨lassical transition.
Zeeya Merali
doi:10.1038/454008a
PLoS stays afloat with bulk publishing p11
Science-publishing firm struggles to make ends meet with open-access model.
Declan Butler
doi:10.1038/454011a
Sidelines p12
Scribbles on the margins of science.
doi:10.1038/454012a
Oil and food costs may bump climate at G8 talks p12
Rich nations and emerging economies join to discuss world's most pressing issues.
Olive Heffernan
doi:10.1038/454012b
Snapshot: Incy Wincy spider p13
Phylogeny of Spiders project offers close-ups of spiders' silk producers.
Rex Dalton
doi:10.1038/454013a
Entomologists jailed for illegal specimen hunt p14
doi:10.1038/454014a
Muslim nuclear physicist sues over freedom of rights p14
doi:10.1038/454014b
Linnean Society celebrates seminal evolution papers p14
doi:10.1038/454014c
Final decision expected on European stem-cell patent p15
doi:10.1038/454015a
Spain awards apes legal rights p15
doi:10.1038/454015b
Pay-off agreed for expert fired after anthrax attacks p15
doi:10.1038/454015c
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Column
Party of OneGetting it across p16
Scientists need a carefully crafted strategy to catch the attention of policy-makers. David Goldston explains.
David Goldston
doi:10.1038/454016a
Top of page
News Feature
Entomology: Battlefield insectica p18
Entomologists are briefing the military on how to protect troops from the scourge of the desert: sandflies. Rex Dalton reports.
doi:10.1038/454018a
Human evolution: Details of being human p21
A difference in one molecule led physician Ajit Varki to question what sets humans apart from other apes. Bruce Lieberman meets a man who sees a big picture in the finer points.
doi:10.1038/454021a
Scientific exploration: What a long, strange trip it's been p24
Launched in 1977, NASA's Voyager missions transformed humanity's view of the Solar System. Now in their fourth decade, they are sending back information about the borderlands of interstellar space (see pages 63–83). Here, three veterans recall details and moments that meant something special along the way.
doi:10.1038/454024a
Top of page
Correspondence
Amateurs as an outreach of HAARP's lunar-echo study p27
Reality lags behind rhetoric in building interdisciplinary work p27
Reduce confusion by using 'design' more intelligently p27
Picture not quite worth 1,000 words in this case p27
Top of page
Books and Arts
Perils of perversity p28
Research is riddled with strong characters; Walter Gratzer applauds a spirited attempt to get their measure.
doi:10.1038/454028a
Bonding as key to hominid origins p29
Primatology meets socio-cultural analysis in a controversial account of human evolution.
doi:10.1038/454029a
Novel alchemy p30
doi:10.1038/454030a
Hidden Treasures: Institute of Physiology collection p31
A cache of beautiful nineteenth-century German scientific devices that has survived many misfortunes now needs a new home, reports Alison Abbott.
Alison Abbott
doi:10.1038/454031a
Top of page
Essays
Science and Music: The ear of the beholder p32
In the last of nine Essays on science and music, John Sloboda argues that researchers must study music as people actually experience it, if they are to understand how it affects thoughts and feelings.
John Sloboda
doi:10.1038/454032a
Arise 'cliodynamics' p34
If we are to learn how to develop a healthy society, we must transform history into an analytical, predictive science, argues Peter Turchin. He has identified intriguing patterns across vastly different times and places.
Peter Turchin
doi:10.1038/454034a
Top of page
News and Views
生命の起源: 原始細胞の透過性はどのくらい？
Origins of life: How leaky were primitive cells? p37
If the first cells were simple vesicles, how did nutrients cross their membranes without help from transport proteins? A model of a primitive cell suggests that early membranes were surprisingly permeable.
David W. Deamer
doi:10.1038/454037a
太陽系: ボイジャー2号からの衝撃のデータ
Solar System: A shock for Voyager 2 p38
The Voyager 2 spacecraft has now followed Voyager 1 into the region beyond the end of the supersonic solar wind, where the influence of interstellar space is growing — so opening a new age of exploration.
J. R. Jokipii
doi:10.1038/454038a
生態学: ニッチ再び
Ecology: Return of the niche p39
Two ideas vie for prominence in community ecology — 'niche partitioning' and 'neutral theory'. A survey of patterns of tree abundance in tropical forest prompts fresh thinking on their respective effects.
Mathew A. Leibold
doi:10.1038/454039a
大気化学: 地球が作り出した太古の光化学スモッグ
Atmospheric chemistry: Her dark materials p41
A glitch in the history of sulphur isotopes could imply that methane emitted by the ancient biosphere created a high-altitude photochemical smog, which governed the climate in a distinctly Gaian way.
Kevin Zahnle
doi:10.1038/454041a
物理化学: 分子がはね返らない場合
Physical chemistry: When molecules don't rebound p43
Picture a simple molecule as two balls attached together by a compressible spring. If an incoming atom strikes one end of the molecule, the spring compresses and the vibrating molecule jumps backwards. Or does it?
Mark Brouard
doi:10.1038/454043a
日本語要約 | Full Text | PDF (200K)
幹細胞: 起動能力に対する注意点
Stem cells: Tips for priming potency p45
Introducing just four specific genes into adult cells causes them to regress to an embryonic stem-cell-like state. At 1%, the efficiency of this process is low, but two tips are at hand on how to make improvements.
Joseph F. Costello
doi:10.1038/454045a
日本語要約 | Full Text | PDF (105K)
気候変動: 海洋の生物多様性と酸性度
Climate change: Acid test for marine biodiversity p46
Rising levels of atmospheric carbon dioxide lead to acidification of the oceans. A site in the Mediterranean, naturally carbonated by under-sea volcanoes, provides clues to the possible effects on marine ecosystems.
Ulf Riebesell
doi:10.1038/454046a
50 & 100 Years Ago p47
doi:10.1038/454047a
Top of page
Articles
統合的ゲノム解析による直接的初期化の分析
Dissecting direct reprogramming through integrative genomic analysis p49
Tarjei S. Mikkelsen, Jacob Hanna, Xiaolan Zhang, Manching Ku, Marius Wernig, Patrick Schorderet, Bradley E. Bernstein, Rudolf Jaenisch, Eric S. Lander & Alexander Meissner
doi:10.1038/nature07056
SMADタンパク質はDROSHAを介したマイクロRNAの成熟を制御する
SMAD proteins control DROSHA-mediated microRNA maturation p56
Brandi N. Davis, Aaron C. Hilyard, Giorgio Lagna & Akiko Hata
doi:10.1038/nature07086
Top of page
Letters
末端衝撃波面における低温のヘリオシースプラズマと風上側の太陽風の減速
Cool heliosheath plasma and deceleration of the upstream solar wind at the termination shock p63
John D. Richardson, Justin C. Kasper, Chi Wang, John W. Belcher & Alan J. Lazarus
doi:10.1038/nature07024
日本語要約 | Full Text | PDF (699K)
非熱的イオンによる太陽風末端衝撃波面の媒介
Mediation of the solar wind termination shock by non-thermal ions p67
R. B. Decker, S. M. Krimigis, E. C. Roelof, M. E. Hill, T. P. Armstrong, G. Gloeckler, D. C. Hamilton & L. J. Lanzerotti
doi:10.1038/nature07030
日本語要約 | Full Text | PDF (557K)
非対称な太陽風末端衝撃波面
An asymmetric solar wind termination shock p71
Edward C. Stone, Alan C. Cummings, Frank B. McDonald, Bryant C. Heikkila, Nand Lal & William R. Webber
doi:10.1038/nature07022
日本語要約 | Full Text | PDF (584K)
太陽風末端衝撃波面における磁場
Magnetic fields at the solar wind termination shock p75
L. F. Burlaga, N. F. Ness, M. H. Acuña, R. P. Lepping, J. E. P. Connerney & J. D. Richardson
doi:10.1038/nature07029
日本語要約 | Full Text | PDF (470K)
太陽風末端衝撃波面およびその付近での強力なプラズマ波
Intense plasma waves at and near the solar wind termination shock p78
中性原子の観測から明らかにされた、衝撃波加速されたピックアップ・イオンが大部分を占めるヘリオシース圧
Domination of heliosheath pressure by shock-accelerated pickup ions from observations of neutral atoms p81
Linghua Wang, Robert P. Lin, Davin E. Larson & Janet G. Luhmann
doi:10.1038/nature07068
ソフトガラス状の流れにおける空間的協同性
Spatial cooperativity in soft glassy flows p84
J. Goyon, A. Colin, G. Ovarlez, A. Ajdari & L. Bocquet
doi:10.1038/nature07026
「綱引き型」非弾性衝突を介した振動励起
Vibrational excitation through tug-of-war inelastic collisions p88
Stuart J. Greaves, Eckart Wrede, Noah T. Goldberg, Jianyang Zhang, Daniel J. Miller & Richard N. Zare
doi:10.1038/nature07079
ジャックヒルで得られたジルコンに含まれるダイヤモンドに記録された軽い炭素貯蔵庫
A light carbon reservoir recorded in zircon-hosted diamond from the Jack Hills p92
Alexander A. Nemchin, Martin J. Whitehouse, Martina Menneken, Thorsten Geisler, Robert T. Pidgeon & Simon A. Wilde
doi:10.1038/nature07102
火山性の二酸化炭素噴出孔から明らかになった、海洋酸性化が生態系に及ぼす影響
Volcanic carbon dioxide vents show ecosystem effects of ocean acidification p96
Jason M. Hall-Spencer, Riccardo Rodolfo-Metalpa, Sophie Martin, Emma Ransome, Maoz Fine, Suzanne M. Turner, Sonia J. Rowley, Dario Tedesco & Maria-Cristina Buia
doi:10.1038/nature07051
絶滅リスクは確率性に寄与する要因に大きく左右される
Extinction risk depends strongly on factors contributing to stochasticity p100
Brett A. Melbourne & Alan Hastings
doi:10.1038/nature06922
Tbx18心外膜細胞に由来する心筋細胞系列
A myocardial lineage derives from Tbx18 epicardial cells p104
Chen-Leng Cai, Jody C. Martin, Yunfu Sun, Li Cui, Lianchun Wang, Kunfu Ouyang, Lei Yang, Lei Bu, Xingqun Liang, Xiaoxue Zhang, William B. Stallcup, Christopher P. Denton, Andrew McCulloch, Ju Chen & Sylvia M. Evans
doi:10.1038/nature06969
日本語要約 | Full Text | PDF (1,620K) | Supplementary information
発生中の心臓では心外膜前駆細胞が心筋細胞系列の一部を担う
Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart p109
Bin Zhou, Qing Ma, Satish Rajagopal, Sean M. Wu, Ibrahim Domian, José Rivera-Feliciano, Dawei Jiang, Alexander von Gise, Sadakatsu Ikeda, Kenneth R. Chien & William T. Pu
doi:10.1038/nature07060
日本語要約 | Full Text | PDF (2,349K) | Supplementary information
線虫の味覚ニューロンの機能的非対称性と走化性におけるその計算的役割
Functional asymmetry in Caenorhabditis elegans taste neurons and its computational role in chemotaxis p114
Hiroshi Suzuki, Tod R. Thiele, Serge Faumont, Marina Ezcurra, Shawn R. Lockery & William R. Schafer
doi:10.1038/nature06927
側坐核でのGluR2欠失型AMPA受容体の形成がコカイン渇望の増幅に関与する
Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving p118
Kelly L. Conrad, Kuei Y. Tseng, Jamie L. Uejima, Jeremy M. Reimers, Li-Jun Heng, Yavin Shaham, Michela Marinelli & Marina E. Wolf
doi:10.1038/nature06995
モデル原始細胞での鋳型の指示に従った遺伝的ポリマーの合成
Template-directed synthesis of a genetic polymer in a model protocell p122
Sheref S. Mansy, Jason P. Schrum, Mathangi Krishnamurthy, Sylvia Tobé, Douglas A. Treco & Jack W. Szostak
doi:10.1038/nature07018
誘導されたncRNAはRNA結合タンパク質アロステリック修飾して転写をシスに阻害する
Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription p126
Xiangting Wang, Shigeki Arai, Xiaoyuan Song, Donna Reichart, Kun Du, Gabriel Pascual, Paul Tempst, Michael G. Rosenfeld, Christopher K. Glass & Riki Kurokawa
doi:10.1038/nature06992
Top of page
Special Report
Career View
Highlights
Naturejobs
ProspectProspects p131
Surveys on careers in academia get mixed interpretations.
Paul Smaglik
doi:10.1038/nj7200-131a
Special Report
Benefits blues p132
As much of the developed world moves to recognize same-sex relationships, gay scientists in some places are swimming against a conservative tide that limits partners' rights. Bryn Nelson reports
Bryn Nelson
doi:10.1038/nj7200-132a
Career View
Sudhansu K. Dey, director of Division of Reproductive Sciences, Cincinnati Children's Research Foundation p134
Reproductive-sciences researcher has made it big since a tough move to the United States.
doi:10.1038/nj7200-134a
Shock physics p134
Shock physics gets a funding jolt.
Virginia Gewin
doi:10.1038/nj7200-134b
Getting people to talk p134
Lab meetings are great. But getting people to participate can be difficult.
Amanda Goh
doi:10.1038/nj7200-134c
Highlights
Opportunities: The National Institutes of Health
doi:10.1038/nj0218
