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Nature 454, xi (3 July 2008) | doi:10.1038/7200xia; Published online 2 July 2008

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Making the paper: Marina Wolf

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Unusual brain receptors weaken resistance to cocaine cravings.

Addicts quitting cocaine are more likely to relapse after several weeks of abstinence than within the first few days: the cues that spark cravings for the drug somehow grow stonger over time. Now there's a physiological explanation for this phenomenon.