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Editorials

This time it's personal p697

The next head of the US National Human Genome Research Institute will need to be equipped to deal with the scientific, political and societal challenges presented by the burgeoning era of personal genomics.

doi:10.1038/453697a


On the campaign trail p697

It is less specific policies and more the approach to science that will distinguish the next US president.

doi:10.1038/453697b


A flood of hard data p698

Social scientists have a new handle on group behaviour — but its causes remain a challenge.

doi:10.1038/453698a


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Research Highlights

Atmospheric science: Blow by blow p700

doi:10.1038/453700a


Biotechnology: Genetic dexterity p700

doi:10.1038/453700b


Plant science: Mossy management p700

doi:10.1038/453700c


Evolution: Genetic bric-a-brac p700

doi:10.1038/453700d


Astronomy: Meal deal p700

doi:10.1038/453700e


Chemical biology: Reducing power p700

doi:10.1038/453700f


Nanotechnology: Sheet change p701

doi:10.1038/453701a


Chemical sensing: Molecular mapping p701

doi:10.1038/453701b


Zoology: Mid-ocean wanderer p701

doi:10.1038/453701c


Correction p701

doi:10.1038/453701d


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Journal Club

Journal club p701

Uri Alon

doi:10.1038/453701e


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News

Russian science academy rejects Putin ally p702

No change at the top as old guard keeps its grip on power.

Quirin Schiermeier

doi:10.1038/453702a


Mars reveals early mysteries p703

Planet's surface proves a puzzle for Phoenix probe.

Eric Hand

doi:10.1038/453703a


Japanese nuclear plant in quake risk p704

Reprocessing facility may be built on active fault.

David Cyranoski

doi:10.1038/453704a


UN decision puts brakes on ocean fertilization p704

Countries agree on moratorium for commercial schemes.

Jeff Tollefson

doi:10.1038/453704b


Physicists to target neutrinos p705

US switches focus from colliders.

Eric Hand

doi:10.1038/453705a


Sidelines p705

Scribbles on the margins of science.

doi:10.1038/453705b


The four-year fight for biological art p707

Steven Kurtz talks about the court battle to clear his name of bioterror links

Rachel Courtland

doi:10.1038/453707a


Here's looking at you, kid p708

Software promises to identify blockbuster scripts.

Zeeya Merali

doi:10.1038/453708a


Biological tools revamp disease classification p709

The role of gene interactions is explored.

Erika Check Hayden

doi:10.1038/453709a


US genomics leader bows out from institute p710

doi:10.1038/453710a


Merck scores victory in three Vioxx appeals p710

doi:10.1038/453710b


Indian coral islands under threat from algae p710

doi:10.1038/453710c


Donation breathes life into Fermilab's balance sheet p711

doi:10.1038/453711a


Researchers kidnapped near Atacama telescope p711

doi:10.1038/453711b


Correction p711

doi:10.1038/453711c


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News Features

Planetary science: Stranger in a strange land p712

Snapshot from Mars captures Phoenix landing.

doi:10.1038/453712a


Ecological modelling: The mathematical mirror to animal nature p714

Animal behaviour is an endless challenge to mathematical modellers. Mark Buchanan looks at how a mathematical principle from physics might be able to explain patterns of movement.

doi:10.1038/453714a


Palaeobiology: The Cambrian smorgasbord p717

Arran Frood asks what current models can teach us about ecological networks half a billion years old.

doi:10.1038/453717a


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Correspondence

Evolutionary theory: it's on the school syllabus in Mexico p719

Antonio Lazcano, Arturo Becerra & Juli Peretó

doi:10.1038/453719a


Evolutionary theory: don't skimp on teaching its history p719

David M. Williams & Malte C. Ebach

doi:10.1038/453719b


Learning to navigate the geography of citation indexes p719

Debbie Chaves

doi:10.1038/453719c


Vaccine failure is not a 'crisis' for HIV research p719

Richard Jefferys

doi:10.1038/453719d


Fixing hiring practices means asking the right question p720

Emilio Artacho

doi:10.1038/453720a


Germline modification carries risk of major social harm p720

Marcy Darnovsky

doi:10.1038/453720b


Global database is needed to support adaptation science p720

Elvira S. Poloczanska, Alistair J. Hobday & Anthony J. Richardson

doi:10.1038/453720c


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Books and Arts

Command and control p721

A biography of botanist Joseph Dalton Hooker illustrates how science switched in the nineteenth century from being a hobby of aristocrats to a profession paid for by governments.

Sandra Knapp reviews Imperial Nature: Joseph Hooker and the Practices of Victorian Science by Jim Endersby

doi:10.1038/453721a


Staving off the global food crisis p722

C. Peter Timmer reviews The End of Food by Paul Roberts

doi:10.1038/453722a

See also: Editor's summary


Horse power unbridled p723

Josie Glausiusz reviews The Horse

doi:10.1038/453723a


How the car became king p724

Marcial Echenique reviews Fighting Traffic: The Dawn of the Motor Age in the American City by Peter D. Norton

doi:10.1038/453724a


In Retrospect: The chromosome trail p725

A new translation of Theodor Boveri's 1914 monograph brings the early origins of contemporary cancer research to a wider readership, contends Robert A. Weinberg.

Robert A. Weinberg reviews Concerning the Origin of Malignant Tumours by Theodor Boveri

doi:10.1038/453725a

See also: Editor's summary


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Essay

Science & Music: Talk of the tone p726

To appreciate how our species makes sense of sound we must study the brain's response to a wide variety of music, languages and musical languages, urges Aniruddh D. Patel.

Aniruddh D. Patel

doi:10.1038/453726a


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News and Views

Genomics: Protein fossils live on as RNA p729

Pseudogenes constitute many of the non-coding DNA sequences that make up large parts of genomes. Once considered merely protein fossils, it now emerges that some of them have active regulatory roles.

Rajkumar Sasidharan & Mark Gerstein

doi:10.1038/453729a

See also: Editor's summary


Attosecond physics: An easier route to high harmony p731

The generation of ultrashort light pulses by atomic ionization and recombination doesn't come cheap. But by niftily exploiting the play of light on a nanostructured surface, it can be done on a table-top.

Mark I. Stockman

doi:10.1038/453731a

See also: Editor's summary


Developmental biology: Order in the lung p733

Given the lung's thousands of branching airways, its development might be expected to be a highly complex process. Yet a surprisingly simple picture now emerges of when, where and in what order these branches form.

David Warburton

doi:10.1038/453733a

See also: Editor's summary


50 & 100 years ago p734

doi:10.1038/453734a


Physical chemistry: Charge states in transition p735

Transition metals come in different oxidation states with different electric charges. So at least we are told at school. Detailed calculations lead to a heretical conclusion — those variable charge states are a myth.

Raffaele Resta

doi:10.1038/453735a

See also: Editor's summary


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News and Views Q&A

Condensed-matter physics: Optical lattices p736

Optical lattices have rapidly become a favoured tool of atomic and condensed-matter physicists. These crystals made of light can be used to trap atoms at very low temperatures, creating a workshop in which to pore over and tinker with fundamental properties of matter.

Markus Greiner & Simon Fölling

doi:10.1038/453736a

See also: Editor's summary


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Articles

The determination of the structure of Saturn's F ring by nearby moonlets p739

Carl D. Murray, Kevin Beurle, Nicholas J. Cooper, Michael W. Evans, Gareth A. Williams & Sébastien Charnoz

doi:10.1038/nature06999

See also: Editor's summary


The branching programme of mouse lung development p745

Ross J. Metzger, Ophir D. Klein, Gail R. Martin & Mark A. Krasnow

doi:10.1038/nature07005

See also: Editor's summary | News and Views by Warburton


A two-tiered mechanism for stabilization and immobilization of E-cadherin p751

Matthieu Cavey, Matteo Rauzi, Pierre-François Lenne & Thomas Lecuit

doi:10.1038/nature06953

See also: Editor's summary


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Letters

High-harmonic generation by resonant plasmon field enhancement p757

Seungchul Kim, Jonghan Jin, Young-Jin Kim, In-Yong Park, Yunseok Kim & Seung-Woo Kim

doi:10.1038/nature07012

See also: Editor's summary | News and Views by Stockman


Superconductivity at 43 K in SmFeAsO1-xFx p761

X. H. Chen, T. Wu, G. Wu, R. H. Liu, H. Chen & D. F. Fang

doi:10.1038/nature07045

See also: Editor's summary


Charge self-regulation upon changing the oxidation state of transition metals in insulators p763

Hannes Raebiger, Stephan Lany & Alex Zunger

doi:10.1038/nature07009

See also: Editor's summary | News and Views by Resta


Hydrogen sulphide release to surface waters at the Precambrian/Cambrian boundary p767

Martin Wille, Thomas F. Nägler, Bernd Lehmann, Stefan Schröder & Jan D. Kramers

doi:10.1038/nature07072

See also: Editor's summary


Simultaneous teleseismic and geodetic observations of the stick–slip motion of an Antarctic ice stream p770

Douglas A. Wiens, Sridhar Anandakrishnan, J. Paul Winberry & Matt A. King

doi:10.1038/nature06990

See also: Editor's summary


Cladistic analysis of continuous modularized traits provides phylogenetic signals in Homo evolution p775

Rolando González-José, Ignacio Escapa, Walter A. Neves, Rubén Cúneo & Héctor M. Pucciarelli

doi:10.1038/nature06891

See also: Editor's summary


Understanding individual human mobility patterns p779

Marta C. González, César A. Hidalgo & Albert-László Barabási

doi:10.1038/nature06958

See also: Editor's summary


Dynamics of fat cell turnover in humans p783

Kirsty L. Spalding, Erik Arner, Pål O. Westermark, Samuel Bernard, Bruce A. Buchholz, Olaf Bergmann, Lennart Blomqvist, Johan Hoffstedt, Erik Näslund, Tom Britton, Hernan Concha, Moustapha Hassan, Mikael Rydén, Jonas Frisén & Peter Arner

doi:10.1038/nature06902

See also: Editor's summary


The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes p788

Austin R. Graves, Patricia K. Curran, Carolyn L. Smith & Joseph A. Mindell

doi:10.1038/nature06907

See also: Editor's summary


Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells p793

Yoshinori Kawamura, Kuniaki Saito, Taishin Kin, Yukiteru Ono, Kiyoshi Asai, Takafumi Sunohara, Tomoko N. Okada, Mikiko C. Siomi & Haruhiko Siomi

doi:10.1038/nature06938

See also: Editor's summary | News and Views by Sasidharan & Gerstein


An endogenous small interfering RNA pathway in Drosophila p798

Benjamin Czech, Colin D. Malone, Rui Zhou, Alexander Stark, Catherine Schlingeheyde, Monica Dus, Norbert Perrimon, Manolis Kellis, James A. Wohlschlegel, Ravi Sachidanandam, Gregory J. Hannon & Julius Brennecke

doi:10.1038/nature07007

See also: Editor's summary | News and Views by Sasidharan & Gerstein


The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs p803

Katsutomo Okamura, Wei-Jen Chung, J. Graham Ruby, Huili Guo, David P. Bartel & Eric C. Lai

doi:10.1038/nature07015

See also: Editor's summary | News and Views by Sasidharan & Gerstein


NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha p807

Jordi Rius, Monica Guma, Christian Schachtrup, Katerina Akassoglou, Annelies S. Zinkernagel, Victor Nizet, Randall S. Johnson, Gabriel G. Haddad & Michael Karin

doi:10.1038/nature06905

See also: Editor's summary


Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation p812

Robert K. McGinty, Jaehoon Kim, Champak Chatterjee, Robert G. Roeder & Tom W. Muir

doi:10.1038/nature06906

See also: Editor's summary


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Naturejobs

Prospect

Prospects p817

Europe aims for more flexibility and job security for researchers.

Paul Smaglik

doi:10.1038/nj7196-817a


Region

Beyond rocket science p818

Huntsville, Alabama, the original home of NASA and of military weapons development, makes a move into biology. Paul Smaglik reports from Rocket City.

Paul Smaglik

doi:10.1038/nj7196-818a


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Futures

The invisible hand p822

A granted wish.

Allan M. Lees

doi:10.1038/453822a


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