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Nature 453, 604-605 (29 May 2008) | doi:10.1038/453604a; Published online 28 May 2008

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Cancer: Whispering sweet somethings

Thea Tlsty1

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That genetic mutations contribute to cancer is undisputed. What now emerges is that a cancer cell's microenvironment has a much stronger hand in the course a cancer takes than previously thought.

The goal of personalized medicine is to tailor a treatment to a specific cellular target at the appropriate stage of a disease, thus 'defusing' the disease process. Cancer is an example of the way in which multifaceted approaches to attaining this goal are emerging.

  1. Thea Tlsty is in the Department of Pathology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, California 94143-0511, USA.
    Email: thea.tlsty@ucsf.edu

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