Supplementary information

This Supplementary Information file contains the following sections:

S1. Supplementary Methods: This section contains additional experimental methods not included in the "Methods" section at the end of the main text. S2. Supplementary Discussion: This section contains additional discussions regarding two questions: (1) What other factors could contribute to the observed level of heterogeneity in Sca-1 within one clonal population (Fig. 1 in the main text)? (2) What biological process may drive the (re)generation of the parental Sca-1 distribution from the three sorted, more homogeneous population fractions? These discussions were originally part of the main text but have been restructured for the Supplementary Information due to considerations for text length. S3. Supplementary Figures and Legends: This section contains experimental supplementary figures along with their legends (Supplementary Figures 1-12). S4. Supplementary Table: This section contains one experimental supplementary table along with its legend (Supplementary Table 1). S5. Theoretical Methods: This is an extended section outlying the theoretical methods employed in the paper, including relevant theoretical supplementary figures (Supplementary Figures 13-18) and tables (Supplementary Table 2-4). S6. Supplementary Notes: This section contains the references for the entire Supplementary Information. The numbering of references here is independent of that for the main text.

This Supplementary Information file contains the following sections: - Download PDF file (1.3MB)