
TY  - JOUR
AU  - Reya, T.
AU  - Morrison, S. J.
AU  - Clarke, M. F.
AU  - Weissman, I. L.
TI  - Stem cells, cancer, and cancer stem cells
JA  - Nature
PY  - 2001///
VL  - 414
SP  - 105
EP  - 111
PB  - Nature Publishing Group
M3  - 10.1038/35102167
N1  - 10.1038/35102167
UR  - http://dx.doi.org/10.1038/35102167
ER  -

TY  - JOUR
AU  - Maser, R. S.
TI  - Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers
JA  - Nature
PY  - 2007///
VL  - 447
SP  - 966
EP  - 971
PB  - Nature Publishing Group
M3  - 10.1038/nature05886
N1  - 10.1038/nature05886
UR  - http://dx.doi.org/10.1038/nature05886
ER  -

TY  - JOUR
AU  - Weng, A. P.
TI  - Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
JA  - Science
PY  - 2004///
VL  - 306
SP  - 269
EP  - 271
PB  - Nature Publishing Group
M3  - 10.1126/science.1102160
N1  - 10.1126/science.1102160
UR  - http://dx.doi.org/10.1126/science.1102160
ER  -

TY  - JOUR
AU  - Fukuda, R.
TI  - Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL)
JA  - Proc. Natl Acad. Sci. USA
PY  - 2005///
VL  - 102
SP  - 15213
EP  - 15218
PB  - Nature Publishing Group
M3  - 10.1073/pnas.0507184102
N1  - 10.1073/pnas.0507184102
UR  - http://dx.doi.org/10.1073/pnas.0507184102
ER  -

TY  - JOUR
AU  - Yilmaz, O. H.
TI  - Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
JA  - Nature
PY  - 2006///
VL  - 441
SP  - 475
EP  - 482
PB  - Nature Publishing Group
M3  - 10.1038/nature04703
N1  - 10.1038/nature04703
UR  - http://dx.doi.org/10.1038/nature04703
ER  -

TY  - JOUR
AU  - Zhang, J.
TI  - PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
JA  - Nature
PY  - 2006///
VL  - 441
SP  - 518
EP  - 522
PB  - Nature Publishing Group
M3  - 10.1038/nature04747
N1  - 10.1038/nature04747
UR  - http://dx.doi.org/10.1038/nature04747
ER  -

TY  - JOUR
AU  - Alva, J. A.
TI  - VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells
JA  - Dev. Dyn.
PY  - 2006///
VL  - 235
SP  - 759
EP  - 767
PB  - Nature Publishing Group
M3  - 10.1002/dvdy.20643
N1  - 10.1002/dvdy.20643
UR  - http://dx.doi.org/10.1002/dvdy.20643
ER  -

TY  - JOUR
AU  - Borowitz, M. J.
AU  - Guenther, K. L.
AU  - Shults, K. E.
AU  - Stelzer, G. T.
TI  - Immunophenotyping of acute leukemia by flow cytometric analysis. Use of CD45 and right-angle light scatter to gate on leukemic blasts in three-color analysis
JA  - Am. J. Clin. Pathol.
PY  - 1993///
VL  - 100
SP  - 534
EP  - 540
PB  - Nature Publishing Group
ER  -

TY  - JOUR
AU  - Soriano, P.
TI  - Generalized lacZ expression with the ROSA26 Cre reporter strain
JA  - Nature Genet.
PY  - 1999///
VL  - 21
SP  - 70
EP  - 71
PB  - Nature Publishing Group
M3  - 10.1038/5007
N1  - 10.1038/5007
UR  - http://dx.doi.org/10.1038/5007
ER  -

TY  - JOUR
AU  - Bonnet, D.
AU  - Dick, J. E.
TI  - Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
JA  - Nature Med.
PY  - 1997///
VL  - 3
SP  - 730
EP  - 737
PB  - Nature Publishing Group
M3  - 10.1038/nm0797-730
N1  - 10.1038/nm0797-730
UR  - http://dx.doi.org/10.1038/nm0797-730
ER  -

TY  - JOUR
AU  - Passegue, E.
AU  - Wagner, E. F.
AU  - Weissman Jun, I. L.
TI  - B deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells
JA  - Cell
PY  - 2004///
VL  - 119
SP  - 431
EP  - 443
PB  - Nature Publishing Group
M3  - 10.1016/j.cell.2004.10.010
N1  - 10.1016/j.cell.2004.10.010
UR  - http://dx.doi.org/10.1016/j.cell.2004.10.010
ER  -

TY  - JOUR
AU  - Castor, A.
TI  - Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia
JA  - Nature Med.
PY  - 2005///
VL  - 11
SP  - 630
EP  - 637
PB  - Nature Publishing Group
M3  - 10.1038/nm1253
N1  - 10.1038/nm1253
UR  - http://dx.doi.org/10.1038/nm1253
ER  -

TY  - JOUR
AU  - Jamieson, C. H.
TI  - Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
JA  - N. Engl. J. Med.
PY  - 2004///
VL  - 351
SP  - 657
EP  - 667
PB  - Nature Publishing Group
M3  - 10.1056/NEJMoa040258
N1  - 10.1056/NEJMoa040258
UR  - http://dx.doi.org/10.1056/NEJMoa040258
ER  -

TY  - JOUR
AU  - Kelly, P. N.
TI  - Tumor growth need not be driven by rare cancer stem cells
JA  - Science
PY  - 2007///
VL  - 317
SP  - 337
PB  - Nature Publishing Group
M3  - 10.1126/science.1142596
N1  - 10.1126/science.1142596
UR  - http://dx.doi.org/10.1126/science.1142596
ER  -

TY  - JOUR
AU  - Reya, T.
TI  - A role for Wnt signalling in self-renewal of haematopoietic stem cells
JA  - Nature
PY  - 2003///
VL  - 423
SP  - 409
EP  - 414
PB  - Nature Publishing Group
M3  - 10.1038/nature01593
N1  - 10.1038/nature01593
UR  - http://dx.doi.org/10.1038/nature01593
ER  -

TY  - JOUR
AU  - Erikson, J.
TI  - Deregulation of c-myc by translocation of the alpha-locus of the T-cell receptor in T-cell leukemias
JA  - Science
PY  - 1986///
VL  - 232
SP  - 884
EP  - 886
PB  - Nature Publishing Group
M3  - 10.1126/science.3486470
N1  - 10.1126/science.3486470
UR  - http://dx.doi.org/10.1126/science.3486470
ER  -

TY  - JOUR
AU  - Boxer, L. M.
AU  - Dang, C. V.
TI  - Translocations involving c-myc and c-myc function
JA  - Oncogene
PY  - 2001///
VL  - 20
SP  - 5595
EP  - 5610
PB  - Nature Publishing Group
M3  - 10.1038/sj.onc.1204595
N1  - 10.1038/sj.onc.1204595
UR  - http://dx.doi.org/10.1038/sj.onc.1204595
ER  -

TY  - JOUR
AU  - Weissman, I.
TI  - Stem cell research: paths to cancer therapies and regenerative medicine
JA  - J. Am. Med. Assoc.
PY  - 2005///
VL  - 294
SP  - 1359
EP  - 1366
PB  - Nature Publishing Group
M3  - 10.1001/jama.294.11.1359
N1  - 10.1001/jama.294.11.1359
UR  - http://dx.doi.org/10.1001/jama.294.11.1359
ER  -

TY  - JOUR
AU  - Shen, W. H.
TI  - Essential role for nuclear PTEN in maintaining chromosomal integrity
JA  - Cell
PY  - 2007///
VL  - 128
SP  - 157
EP  - 170
PB  - Nature Publishing Group
M3  - 10.1016/j.cell.2006.11.042
N1  - 10.1016/j.cell.2006.11.042
UR  - http://dx.doi.org/10.1016/j.cell.2006.11.042
ER  -

TY  - JOUR
AU  - Palomero, T.
TI  - NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
JA  - Proc. Natl Acad. Sci. USA
PY  - 2006///
VL  - 103
SP  - 18261
EP  - 18266
PB  - Nature Publishing Group
M3  - 10.1073/pnas.0606108103
N1  - 10.1073/pnas.0606108103
UR  - http://dx.doi.org/10.1073/pnas.0606108103
ER  -

TY  - JOUR
AU  - Sharma, V. M.
TI  - Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc
JA  - Mol. Cell. Biol.
PY  - 2006///
VL  - 26
SP  - 8022
EP  - 8031
PB  - Nature Publishing Group
M3  - 10.1128/MCB.01091-06
N1  - 10.1128/MCB.01091-06
UR  - http://dx.doi.org/10.1128/MCB.01091-06
ER  -

TY  - JOUR
AU  - Weng, A. P.
TI  - c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
JA  - Genes Dev.
PY  - 2006///
VL  - 20
SP  - 2096
EP  - 2109
PB  - Nature Publishing Group
M3  - 10.1101/gad.1450406
N1  - 10.1101/gad.1450406
UR  - http://dx.doi.org/10.1101/gad.1450406
ER  -

TY  - JOUR
AU  - Palomero, T.
TI  - Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
JA  - Nature Med.
PY  - 2007///
VL  - 13
SP  - 1203
EP  - 1210
PB  - Nature Publishing Group
M3  - 10.1038/nm1636
N1  - 10.1038/nm1636
UR  - http://dx.doi.org/10.1038/nm1636
ER  -

TY  - JOUR
AU  - Lesche, R.
TI  - Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene
JA  - Genesis
PY  - 2002///
VL  - 32
SP  - 148
EP  - 149
PB  - Nature Publishing Group
M3  - 10.1002/gene.10036
N1  - 10.1002/gene.10036
UR  - http://dx.doi.org/10.1002/gene.10036
ER  -

TY  - JOUR
AU  - Brault, V.
TI  - Inactivation of the [bgr]-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development
JA  - Development
PY  - 2001///
VL  - 128
SP  - 1253
EP  - 1264
PB  - Nature Publishing Group
ER  -

TY  - JOUR
AU  - Putti, M. C.
TI  - Expression of myeloid markers lacks prognostic impact in children treated for acute lymphoblastic leukemia: Italian experience in AIEOP-ALL 88-91 studies
JA  - Blood
PY  - 1998///
VL  - 92
SP  - 795
EP  - 801
PB  - Nature Publishing Group
ER  -

TY  - JOUR
AU  - Boomer, T.
TI  - Detection of E2A translocations in leukemias via fluorescence in situ hybridization
JA  - Leukemia
PY  - 2001///
VL  - 15
SP  - 95
EP  - 102
PB  - Nature Publishing Group
M3  - 10.1038/sj.leu.2401988
N1  - 10.1038/sj.leu.2401988
UR  - http://dx.doi.org/10.1038/sj.leu.2401988
ER  -
