Table of contents

indicates content that is available online only

Making the paper: Julie Theriot pxi

Mechanism for cell shapeliness decoded from fish scales.

doi:10.1038/7194xia


Abstractions pxi

doi:10.1038/7194xib


From the blogosphere pxi

doi:10.1038/7194xic


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Editorials

Two symbols, one solution p427

Saving a handful of photogenic species — or iconic rainforests — is no substitute for a comprehensive plan that deals with climate, economics and the environment together.

doi:10.1038/453427a


Trials on trial p427

The Food and Drug Administration should rethink its rejection of the Declaration of Helsinki.

doi:10.1038/453427b


The Universe at home p428

The digitization of astronomy is a transformation and a delight for both amateurs and professionals.

doi:10.1038/453428a


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Research Highlights

Geology: Fjord focus p430

doi:10.1038/453430a


Microscopy: Enter, the nanoscope p430

doi:10.1038/453430b


Zoology: Less than slothful p430

doi:10.1038/453430c


Chemistry: Up close and structural p430

doi:10.1038/453430d


Molecular biology: AAAAnswers p430

doi:10.1038/453430e


Population biology: Keep off the grass p430

doi:10.1038/453430f


Genetics: Self defence p431

doi:10.1038/453431a


Inorganic chemistry: Towards a noble line p431

doi:10.1038/453431b


Plant science: Monster fruit p431

doi:10.1038/453431c


Human reproduction: Fertile tones p431

doi:10.1038/453431d


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Journal Club

Journal club p431

Andrea Manica

doi:10.1038/453431e


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News

Polar bear numbers set to fall p432

Climate-change icon gains 'threatened' status from United States.

Rachel Courtland

doi:10.1038/453432a


Whales are on the rise p433

Humpback population shows signs of recovery.

Rex Dalton

doi:10.1038/453433a


Meeting urges scientists into politics p434

Advice on how to ditch the lab for elected office.

Gene Russo

doi:10.1038/453434a


Sterile mosquitoes near take-off p435

Malaysia prepares to fight dengue with GM insects.

David Cyranoski

doi:10.1038/453435a


Sidelines p435

Scribbles on the margins of science.

doi:10.1038/453435b


No star left behind p437

An open-source software project could help unify every existing astronomical image into a single data set.

Eric Hand

doi:10.1038/453437a


Poland tackles science like a business p438

Science minister Barbara Kudrycka talks reform.

Barbara Kudrycka

doi:10.1038/453438a


US plans more primate research p439

HIV and clinical research drive up demand for experiments.

Erika Check Hayden

doi:10.1038/453439a


Parkinson's researchers join forces with gene tester p441

doi:10.1038/453441a


Europe considers plans for manned spacecraft p441

doi:10.1038/453441b


British parliament backs hybrid embryos p441

doi:10.1038/453441c


Cosmic dust hides true brightness of Universe p441

doi:10.1038/453441d


NOAA chief backs bid for climate-change agency p441

doi:10.1038/453441e


Cancer forces Tasmanian devil onto endangered list p441

doi:10.1038/453441f


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News Features

Eyewitness identification: Line-ups on trial p442

A major, but flawed, study of identity parades, or line-ups, has set science and the police at odds. Laura Spinney investigates.

doi:10.1038/453442a


Language: The language barrier p446

Some researchers think that the evolution of languages can be understood by treating them like genomes — but many linguists don't want to hear about it. Emma Marris reports.

doi:10.1038/453446a


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Correspondence

Acceptance of peer review will free Italy's research slaves p449

Ignazio R. Marino

doi:10.1038/453449a


Mimicking photosynthesis, but just the best bits p449

A. William Rutherford & Thomas A. Moore

doi:10.1038/453449b


Standard identifier could mobilize data and free time p449

Dave Roberts & Vishwas Chavan

doi:10.1038/453449c


Name variations can hit citation rankings p450

Biji T. Kurien

doi:10.1038/453450a


Names: dropped to avoid prejudice, now useful again p450

Prabhu B. Patil

doi:10.1038/453450b


Open-access more harm than good in developing world p450

Raghavendra Gadagkar

doi:10.1038/453450c


A 3D revolution in communicating science p450

Jérôme Murienne, Alexander Ziegler & Bernhard Ruthensteiner

doi:10.1038/453450d


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Books and Arts

Security in an uncertain world p451

Biological protection systems that have evolved over billions of years could be the key to strengthening national defences against unforeseen threats, says Jessica Flack.

doi:10.1038/453451a


Genetic medicine at the bedside p452

doi:10.1038/453452a


A rough guide to Titan p453

doi:10.1038/453453a


Culture dish p453

doi:10.1038/453453b


How science hit the small screen p454

doi:10.1038/453454a


Super clothes with special powers p455

doi:10.1038/453455a


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Essay

Science & Music: Lost in music p456

Music provides unique opportunities for understanding both brain and culture. But globalization means that time is running out, warns David Huron, for the quest to encounter the range of possible musical minds.

David Huron

doi:10.1038/453456a


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News and Views

レーザー技術: 虹の彼方

Laser technology: Over the rainbow p459

Many laser diodes provide light in only a limited range of the visible spectrum. A hybrid laser made out of plastic, driven by a high-power light-emitting diode, looks to offer a more flexible approach.

John M. Lupton

doi:10.1038/453459a


細胞生物学: 分解を行う2本の手

Cell biology: Two hands for degradation p460

Living cells must do away with regulatory proteins that are not needed. News comes of a considerable advance in understanding how the main agent of destruction, the proteasome, catches its targets.

Yasushi Saeki & Keiji Tanaka

doi:10.1038/453460a


生物物理: 細胞が這い回り用の形態をとる仕組み

Biophysics: Cells get in shape for a crawl p461

A cell's shape changes as it moves along a surface. The forward-thinking cytoskeletal elements are all for progress, but the conservative cell membrane keeps them under control by physically opposing their movement.

Jason M. Haugh

doi:10.1038/453461a


天文学: いきなり登場した超新星

Astronomy: Supernova bursts onto the scene p462

The stellar explosions known as supernovae are spectacular but common cosmic events. A satellite telescope's chance observation of a burst of X-ray light might be the first record of a supernova's earliest minutes.

Roger Chevalier

doi:10.1038/453462a


構造生物学: DNA修復のスナップショット

Structural biology: Snapshots of DNA repair p463

In recombinational DNA repair, nearly identical sequences in chromosomes are found and swapped. Structures of the RecA–DNA complexes involved provide insight into the mechanism and energetics of this universal process.

Stephen C. Kowalczykowski

doi:10.1038/453463a


50 & 100 years ago p465

doi:10.1038/453465a


細胞生物学: ウイルスのカムフラージュ

Cell biology: Viruses in camouflage p466

The vaccinia virus acts like a Trojan Horse to enter its host cells: it envelops itself in the membrane of a dying cell, and is then taken up by healthy cells.

Kirsten Sandvig & Bo van Deurs

doi:10.1038/453466a


Correction p467

doi:10.1038/453467a


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Articles

超新星誕生時の極めて明るいX線アウトバースト

An extremely luminous X-ray outburst at the birth of a supernova p469

A. M. Soderberg, E. Berger, K. L. Page, P. Schady, J. Parrent, D. Pooley, X.-Y. Wang, E. O. Ofek, A. Cucchiara, A. Rau, E. Waxman, J. D. Simon, D. C.-J. Bock, P. A. Milne, M. J. Page, J. C. Barentine, S. D. Barthelmy, A. P. Beardmore, M. F. Bietenholz, P. Brown, A. Burrows, D. N. Burrows, G. Byrngelson, S. B. Cenko, P. Chandra, J. R. Cummings, D. B. Fox, A. Gal-Yam, N. Gehrels, S. Immler, M. Kasliwal, A. K. H. Kong, H. A. Krimm, S. R. Kulkarni, T. J. Maccarone, P. Mészáros, E. Nakar, P. T. O'Brien, R. A. Overzier, M. de Pasquale, J. Racusin, N. Rea & D. G. York

doi:10.1038/nature06997


運動性細胞の形態決定機構

Mechanism of shape determination in motile cells p475

Kinneret Keren, Zachary Pincus, Greg M. Allen, Erin L. Barnhart, Gerard Marriott, Alex Mogilner & Julie A. Theriot

doi:10.1038/nature06952


プロテアソームのサブユニットRpn13は新規なユビキチン受容体である

Proteasome subunit Rpn13 is a novel ubiquitin receptor p481

Koraljka Husnjak, Suzanne Elsasser, Naixia Zhang, Xiang Chen, Leah Randles, Yuan Shi, Kay Hofmann, Kylie J. Walters, Daniel Finley & Ivan Dikic

doi:10.1038/nature06926


RecA-ssDNA/dsDNAの構造から示される相同組み換えの機構

Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures p489

Zhucheng Chen, Haijuan Yang & Nikola P. Pavletich

doi:10.1038/nature06971


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Letters

光のレヴィ・フライト

A Lévy flight for light p495

Pierre Barthelemy, Jacopo Bertolotti & Diederik S. Wiersma

doi:10.1038/nature06948


短距離引力をもつ粒子のゲル化

Gelation of particles with short-range attraction p499

Peter J. Lu, Emanuela Zaccarelli, Fabio Ciulla, Andrew B. Schofield, Francesco Sciortino & David A. Weitz

doi:10.1038/nature06931


原生代後期における氷期後のCO2濃度上昇を示す三酸素同位体組成の証拠

Triple oxygen isotope evidence for elevated CO2 levels after a Neoproterozoic glaciation p504

Huiming Bao, J. R. Lyons & Chuanming Zhou

doi:10.1038/nature06959


地震活動を生む溶岩と爆発的噴火の予測

Seismogenic lavas and explosive eruption forecasting p507

Y. Lavallée, P. G. Meredith, D. B. Dingwell, K.-U. Hess, J. Wassermann, B. Cordonnier, A. Gerik & J. H. Kruhl

doi:10.1038/nature06980


地震を発生する珪長質マグマの破壊に対する証拠

Evidence for seismogenic fracture of silicic magma p511

Hugh Tuffen, Rosanna Smith & Peter R. Sammonds

doi:10.1038/nature06989


テキサス州ペルム紀前期層で出土した原始的なカエル類と、カエルおよびサンショウウオの起源

A stem batrachian from the Early Permian of Texas and the origin of frogs and salamanders p515

Jason S. Anderson, Robert R. Reisz, Diane Scott, Nadia B. Fröbisch & Stuart S. Sumida

doi:10.1038/nature06865


胚性幹細胞自己複製の基底状態

The ground state of embryonic stem cell self-renewal p519

Qi-Long Ying, Jason Wray, Jennifer Nichols, Laura Batlle-Morera, Bradley Doble, James Woodgett, Philip Cohen & Austin Smith

doi:10.1038/nature06968


ヒト心血管前駆細胞はKDR+胚性幹細胞に由来する細胞集団から発生する

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population p524

Lei Yang, Mark H. Soonpaa, Eric D. Adler, Torsten K. Roepke, Steven J. Kattman, Marion Kennedy, Els Henckaerts, Kristina Bonham, Geoffrey W. Abbott, R. Michael Linden, Loren J. Field & Gordon M. Keller

doi:10.1038/nature06894


Pten欠損白血病幹細胞の形成には、複数の遺伝的事象が協同的に寄与している

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation p529

Wei Guo, Joseph L. Lasky, Chun-Ju Chang, Sherly Mosessian, Xiaoman Lewis, Yun Xiao, Jennifer E. Yeh, James Y. Chen, M. Luisa Iruela-Arispe, Marileila Varella-Garcia & Hong Wu

doi:10.1038/nature06933


偽遺伝子由来の低分子干渉RNAはマウス卵母細胞で遺伝子発現を調節する

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes p534

Oliver H. Tam, Alexei A. Aravin, Paula Stein, Angelique Girard, Elizabeth P. Murchison, Sihem Cheloufi, Emily Hodges, Martin Anger, Ravi Sachidanandam, Richard M. Schultz & Gregory J. Hannon

doi:10.1038/nature06904


マウスの卵母細胞では、自然に形成されたdsRNA由来の内在性siRNAが転写産物を調節する

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes p539

Toshiaki Watanabe, Yasushi Totoki, Atsushi Toyoda, Masahiro Kaneda, Satomi Kuramochi-Miyagawa, Yayoi Obata, Hatsune Chiba, Yuji Kohara, Tomohiro Kono, Toru Nakano, M. Azim Surani, Yoshiyuki Sakaki & Hiroyuki Sasaki

doi:10.1038/nature06908


哺乳類前駆細胞での全トランスクリプトームノイズによる細胞系譜の制御

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells p544

Hannah H. Chang, Martin Hemberg, Mauricio Barahona, Donald E. Ingber & Sui Huang

doi:10.1038/nature06965


新規なプレクストリン相同ドメイン相互作用を介した、プロテアソームにおけるユビキチンドッキング

Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction p548

Patrick Schreiner, Xiang Chen, Koraljka Husnjak, Leah Randles, Naixia Zhang, Suzanne Elsasser, Daniel Finley, Ivan Dikic, Kylie J. Walters & Michael Groll

doi:10.1038/nature06924


微胞子虫Encephalitozoon cuniculiの残存ミトコンドリアによる新しいATP獲得経路

A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi p553

Anastasios D. Tsaousis, Edmund R. S. Kunji, Alina V. Goldberg, John M. Lucocq, Robert P. Hirt & T. Martin Embley

doi:10.1038/nature06903


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Naturejobs

Prospect

Prospects p557

Energy-related jobs could be on the rise for years to come.

Paul Smaglik

doi:10.1038/nj7194-557a


Region

Westernizing Eastern-bloc science p558

Scientists in newer member countries are learning how to use what the European Union offers.

Quirin Schiermeier

doi:10.1038/nj7194-558a


Career View

Frank Torti, chief scientist, US Food and Drug Administration p560

New FDA science chief faces serious challenges.

Virginia Gewin

doi:10.1038/nj7194-560a


Upping student numbers and diversity p560

Undergraduate research awardees emphasize diversity.

Virginia Gewin

doi:10.1038/nj7194-560b


An impassive observation p560

An impassioned observer.

Aliza le Roux

doi:10.1038/nj7194-560c


Spotlight

Spotlight on Alabama

doi:10.1038/nj0211


Highlights

Highlight on Spain

doi:10.1038/nj0212


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Futures

The Neanderthal correlation p562

A question of breeding.

Jeff Hecht

doi:10.1038/453562a


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