Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 453, 463-466 (22 May 2008) | doi:10.1038/453463a; Published online 21 May 2008
Open Innovation Challenges
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
- More Challenges
- Powered by:
nature jobs
Organic Chemistry
- Praj Matrix - Praj Industries Ltd
- Pune, Maharashtra Pune-411021 India
Senior Researcher in theoretical chemistry / physics
- Italian Institute of Technology
- Lecce, Italy
Structural biology: Snapshots of DNA repair
Stephen C. Kowalczykowski1
Abstract
In recombinational DNA repair, nearly identical sequences in chromosomes are found and swapped. Structures of the RecA–DNA complexes involved provide insight into the mechanism and energetics of this universal process.
Homologous recombination is one of the many processes used by cells to repair damaged DNA and to diversify their genomes. A central step in recombination involves the exchange of DNA strands between identical, or nearly identical, segments of chromosomes.
- Stephen C. Kowalczykowski is in the Departments of Microbiology, and of Molecular and Cellular Biology, University of California, Davis, One Shields Avenue, Davis, California 95616, USA.
Email: sckowalczykowski@ucdavis.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Cancer Catalyst of a catalystNature News and Views (10 Feb 2005)
Molecular mimicry connects BRCA2 to Rad51 and recombinational DNA repairNature Structural Biology News and Views (01 Dec 2002)
See all 4 matches for News And ViewsRESEARCH
Mechanism of RecA-mediated homologous recombination revisited by single molecule nanomanipulationThe EMBO Journal Article (20 Sep 2006)
Mechanism of homologous recombination from the RecA?ssDNA/dsDNA structuresNature Article (22 May 2008)
See all 54 matches for Research