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Nature 453, 461-462 (22 May 2008) | doi:10.1038/453461a; Published online 21 May 2008
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Biophysics: Cells get in shape for a crawl
Jason M. Haugh1
Abstract
A cell's shape changes as it moves along a surface. The forward-thinking cytoskeletal elements are all for progress, but the conservative cell membrane keeps them under control by physically opposing their movement.
The ability of living cells to move affects the way our bodies develop, fight off infections and heal wounds. Moreover, cell migration is an extremely complex process, which explains why it has captured the collective imaginations of a variety of fields, from the biological and the physical sciences.
- Jason M. Haugh is in the Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina 27695–7905, USA.
Email: jason_haugh@ncsu.edu
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Mechanism of shape determination in motile cellsNature Article (22 May 2008)
