Table of contents
Volume 453 Number 7194 pp427-562
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Editorials
Two symbols, one solution p427
Saving a handful of photogenic species — or iconic rainforests — is no substitute for a comprehensive plan that deals with climate, economics and the environment together.
doi:10.1038/453427a
Trials on trial p427
The Food and Drug Administration should rethink its rejection of the Declaration of Helsinki.
doi:10.1038/453427b
The Universe at home p428
The digitization of astronomy is a transformation and a delight for both amateurs and professionals.
doi:10.1038/453428a
Research Highlights
Geology: Fjord focus p430
doi:10.1038/453430a
Microscopy: Enter, the nanoscope p430
doi:10.1038/453430b
Zoology: Less than slothful p430
doi:10.1038/453430c
Chemistry: Up close and structural p430
doi:10.1038/453430d
Molecular biology: AAAAnswers p430
doi:10.1038/453430e
Population biology: Keep off the grass p430
doi:10.1038/453430f
Genetics: Self defence p431
doi:10.1038/453431a
Inorganic chemistry: Towards a noble line p431
doi:10.1038/453431b
Plant science: Monster fruit p431
doi:10.1038/453431c
Human reproduction: Fertile tones p431
doi:10.1038/453431d
News
Polar bear numbers set to fall p432
Climate-change icon gains 'threatened' status from United States.
Rachel Courtland
doi:10.1038/453432a
Whales are on the rise p433
Humpback population shows signs of recovery.
Rex Dalton
doi:10.1038/453433a
Meeting urges scientists into politics p434
Advice on how to ditch the lab for elected office.
Gene Russo
doi:10.1038/453434a
Sterile mosquitoes near take-off p435
Malaysia prepares to fight dengue with GM insects.
David Cyranoski
doi:10.1038/453435a
Sidelines p435
Scribbles on the margins of science.
doi:10.1038/453435b
No star left behind p437
An open-source software project could help unify every existing astronomical image into a single data set.
Eric Hand
doi:10.1038/453437a
Poland tackles science like a business p438
Science minister Barbara Kudrycka talks reform.
Barbara Kudrycka
doi:10.1038/453438a
US plans more primate research p439
HIV and clinical research drive up demand for experiments.
Erika Check Hayden
doi:10.1038/453439a
Parkinson's researchers join forces with gene tester p441
doi:10.1038/453441a
Europe considers plans for manned spacecraft p441
doi:10.1038/453441b
British parliament backs hybrid embryos p441
doi:10.1038/453441c
Cosmic dust hides true brightness of Universe p441
doi:10.1038/453441d
NOAA chief backs bid for climate-change agency p441
doi:10.1038/453441e
Cancer forces Tasmanian devil onto endangered list p441
doi:10.1038/453441f
News Features
Eyewitness identification: Line-ups on trial p442
A major, but flawed, study of identity parades, or line-ups, has set science and the police at odds. Laura Spinney investigates.
doi:10.1038/453442a
Language: The language barrier p446
Some researchers think that the evolution of languages can be understood by treating them like genomes — but many linguists don't want to hear about it. Emma Marris reports.
doi:10.1038/453446a
Correspondence
Acceptance of peer review will free Italy's research slaves p449
Ignazio R. Marino
doi:10.1038/453449a
Mimicking photosynthesis, but just the best bits p449
A. William Rutherford & Thomas A. Moore
doi:10.1038/453449b
Standard identifier could mobilize data and free time p449
Dave Roberts & Vishwas Chavan
doi:10.1038/453449c
Name variations can hit citation rankings p450
Biji T. Kurien
doi:10.1038/453450a
Names: dropped to avoid prejudice, now useful again p450
Prabhu B. Patil
doi:10.1038/453450b
Open-access more harm than good in developing world p450
Raghavendra Gadagkar
doi:10.1038/453450c
A 3D revolution in communicating science p450
Jérôme Murienne, Alexander Ziegler & Bernhard Ruthensteiner
doi:10.1038/453450d
Books and Arts
Security in an uncertain world p451
Biological protection systems that have evolved over billions of years could be the key to strengthening national defences against unforeseen threats, says Jessica Flack.
Jessica Flack reviews Natural Security: A Darwinian Approach to a Dangerous World
doi:10.1038/453451a
Genetic medicine at the bedside p452
Hugh Young Rienhoff Jr reviews Heredity and Hope: The Case for Genetic Screening by Ruth Schwartz Cowan
doi:10.1038/453452a
A rough guide to Titan p453
Henry Roe reviews Titan Unveiled: Saturn's Mysterious Moon Explored by Ralph Lorenz & Jacqueline Mitton
doi:10.1038/453453a
Culture dish p453
doi:10.1038/453453b
How science hit the small screen p454
Colin Martin reviews Films of Fact
doi:10.1038/453454a
Super clothes with special powers p455
Josie Glausiusz reviews Superheroes: Fashion and Fantasy
doi:10.1038/453455a
Essay
Science & Music: Lost in music p456
Music provides unique opportunities for understanding both brain and culture. But globalization means that time is running out, warns David Huron, for the quest to encounter the range of possible musical minds.
David Huron
doi:10.1038/453456a
News and Views
Laser technology: Over the rainbow p459
Many laser diodes provide light in only a limited range of the visible spectrum. A hybrid laser made out of plastic, driven by a high-power light-emitting diode, looks to offer a more flexible approach.
John M. Lupton
doi:10.1038/453459a
Cell biology: Two hands for degradation p460
Living cells must do away with regulatory proteins that are not needed. News comes of a considerable advance in understanding how the main agent of destruction, the proteasome, catches its targets.
Yasushi Saeki & Keiji Tanaka
doi:10.1038/453460a
See also: Editor's summary
Biophysics: Cells get in shape for a crawl p461
A cell's shape changes as it moves along a surface. The forward-thinking cytoskeletal elements are all for progress, but the conservative cell membrane keeps them under control by physically opposing their movement.
Jason M. Haugh
doi:10.1038/453461a
See also: Editor's summary
Astronomy: Supernova bursts onto the scene p462
The stellar explosions known as supernovae are spectacular but common cosmic events. A satellite telescope's chance observation of a burst of X-ray light might be the first record of a supernova's earliest minutes.
Roger Chevalier
doi:10.1038/453462a
See also: Editor's summary
Structural biology: Snapshots of DNA repair p463
In recombinational DNA repair, nearly identical sequences in chromosomes are found and swapped. Structures of the RecA–DNA complexes involved provide insight into the mechanism and energetics of this universal process.
Stephen C. Kowalczykowski
doi:10.1038/453463a
See also: Editor's summary
50 & 100 years ago p465
doi:10.1038/453465a
Cell biology: Viruses in camouflage p466
The vaccinia virus acts like a Trojan Horse to enter its host cells: it envelops itself in the membrane of a dying cell, and is then taken up by healthy cells.
Kirsten Sandvig & Bo van Deurs
doi:10.1038/453466a
Correction p467
doi:10.1038/453467a
Articles
An extremely luminous X-ray outburst at the birth of a supernova p469
A. M. Soderberg, E. Berger, K. L. Page, P. Schady, J. Parrent, D. Pooley, X.-Y. Wang, E. O. Ofek, A. Cucchiara, A. Rau, E. Waxman, J. D. Simon, D. C.-J. Bock, P. A. Milne, M. J. Page, J. C. Barentine, S. D. Barthelmy, A. P. Beardmore, M. F. Bietenholz, P. Brown, A. Burrows, D. N. Burrows, G. Byrngelson, S. B. Cenko, P. Chandra, J. R. Cummings, D. B. Fox, A. Gal-Yam, N. Gehrels, S. Immler, M. Kasliwal, A. K. H. Kong, H. A. Krimm, S. R. Kulkarni, T. J. Maccarone, P. Mészáros, E. Nakar, P. T. O'Brien, R. A. Overzier, M. de Pasquale, J. Racusin, N. Rea & D. G. York
doi:10.1038/nature06997
Abstract | Full Text | PDF (755K) | Supplementary information
See also: Editor's summary | News and Views by Chevalier
Mechanism of shape determination in motile cells p475
Kinneret Keren, Zachary Pincus, Greg M. Allen, Erin L. Barnhart, Gerard Marriott, Alex Mogilner & Julie A. Theriot
doi:10.1038/nature06952
Abstract | Full Text | PDF (1,739K) | Supplementary information
See also: Editor's summary | News and Views by Haugh
Proteasome subunit Rpn13 is a novel ubiquitin receptor p481
Koraljka Husnjak, Suzanne Elsasser, Naixia Zhang, Xiang Chen, Leah Randles, Yuan Shi, Kay Hofmann, Kylie J. Walters, Daniel Finley & Ivan Dikic
doi:10.1038/nature06926
PDB code
3D view
Abstract | Full Text | PDF (1,489K) | Supplementary information
See also: Editor's summary | News and Views by Saeki & Tanaka
Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures p489
Zhucheng Chen, Haijuan Yang & Nikola P. Pavletich
doi:10.1038/nature06971
Abstract | Full Text | PDF (1,471K) | Supplementary information
See also: Editor's summary | News and Views by Kowalczykowski
Letters
A Lévy flight for light p495
Pierre Barthelemy, Jacopo Bertolotti & Diederik S. Wiersma
doi:10.1038/nature06948
First paragraph | Full Text | PDF (1,215K) | Supplementary information
See also: Editor's summary
Gelation of particles with short-range attraction p499
Peter J. Lu, Emanuela Zaccarelli, Fabio Ciulla, Andrew B. Schofield, Francesco Sciortino & David A. Weitz
doi:10.1038/nature06931
First paragraph | Full Text | PDF (842K) | Supplementary information
See also: Editor's summary
Triple oxygen isotope evidence for elevated CO2 levels after a Neoproterozoic glaciation p504
Huiming Bao, J. R. Lyons & Chuanming Zhou
doi:10.1038/nature06959
First paragraph | Full Text | PDF (368K) | Supplementary information
See also: Editor's summary
Seismogenic lavas and explosive eruption forecasting p507
Y. Lavallée, P. G. Meredith, D. B. Dingwell, K.-U. Hess, J. Wassermann, B. Cordonnier, A. Gerik & J. H. Kruhl
doi:10.1038/nature06980
First paragraph | Full Text | PDF (474K) | Supplementary information
See also: Editor's summary
Evidence for seismogenic fracture of silicic magma p511
Hugh Tuffen, Rosanna Smith & Peter R. Sammonds
doi:10.1038/nature06989
First paragraph | Full Text | PDF (418K) | Supplementary information
See also: Editor's summary
A stem batrachian from the Early Permian of Texas and the origin of frogs and salamanders p515
Jason S. Anderson, Robert R. Reisz, Diane Scott, Nadia B. Fröbisch & Stuart S. Sumida
doi:10.1038/nature06865
First paragraph | Full Text | PDF (1,521K) | Supplementary information
See also: Editor's summary
The ground state of embryonic stem cell self-renewal p519
Qi-Long Ying, Jason Wray, Jennifer Nichols, Laura Batlle-Morera, Bradley Doble, James Woodgett, Philip Cohen & Austin Smith
doi:10.1038/nature06968
First paragraph | Full Text | PDF (1,138K) | Supplementary information
See also: Editor's summary
Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population p524
Lei Yang, Mark H. Soonpaa, Eric D. Adler, Torsten K. Roepke, Steven J. Kattman, Marion Kennedy, Els Henckaerts, Kristina Bonham, Geoffrey W. Abbott, R. Michael Linden, Loren J. Field & Gordon M. Keller
doi:10.1038/nature06894
First paragraph | Full Text | PDF (1,063K) | Supplementary information
See also: Editor's summary
Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation p529
Wei Guo, Joseph L. Lasky, Chun-Ju Chang, Sherly Mosessian, Xiaoman Lewis, Yun Xiao, Jennifer E. Yeh, James Y. Chen, M. Luisa Iruela-Arispe, Marileila Varella-Garcia & Hong Wu
doi:10.1038/nature06933
First paragraph | Full Text | PDF (793K) | Supplementary information
See also: Editor's summary
Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes p534
Oliver H. Tam, Alexei A. Aravin, Paula Stein, Angelique Girard, Elizabeth P. Murchison, Sihem Cheloufi, Emily Hodges, Martin Anger, Ravi Sachidanandam, Richard M. Schultz & Gregory J. Hannon
doi:10.1038/nature06904
First paragraph | Full Text | PDF (465K) | Supplementary information
See also: Editor's summary
Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes p539
Toshiaki Watanabe, Yasushi Totoki, Atsushi Toyoda, Masahiro Kaneda, Satomi Kuramochi-Miyagawa, Yayoi Obata, Hatsune Chiba, Yuji Kohara, Tomohiro Kono, Toru Nakano, M. Azim Surani, Yoshiyuki Sakaki & Hiroyuki Sasaki
doi:10.1038/nature06908
First paragraph | Full Text | PDF (382K) | Supplementary information
See also: Editor's summary
Transcriptome-wide noise controls lineage choice in mammalian progenitor cells p544
Hannah H. Chang, Martin Hemberg, Mauricio Barahona, Donald E. Ingber & Sui Huang
doi:10.1038/nature06965
First paragraph | Full Text | PDF (711K) | Supplementary information
See also: Editor's summary
Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction p548
Patrick Schreiner, Xiang Chen, Koraljka Husnjak, Leah Randles, Naixia Zhang, Suzanne Elsasser, Daniel Finley, Ivan Dikic, Kylie J. Walters & Michael Groll
doi:10.1038/nature06924
First paragraph | Full Text | PDF (896K) | Supplementary information
See also: Editor's summary | News and Views by Saeki & Tanaka
A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi p553
Anastasios D. Tsaousis, Edmund R. S. Kunji, Alina V. Goldberg, John M. Lucocq, Robert P. Hirt & T. Martin Embley
doi:10.1038/nature06903
First paragraph | Full Text | PDF (789K) | Supplementary information
See also: Editor's summary
Naturejobs
ProspectProspects p557
Energy-related jobs could be on the rise for years to come.
Paul Smaglik
doi:10.1038/nj7194-557a
Region
Westernizing Eastern-bloc science p558
Scientists in newer member countries are learning how to use what the European Union offers.
Quirin Schiermeier
doi:10.1038/nj7194-558a
Career View
Frank Torti, chief scientist, US Food and Drug Administration p560
New FDA science chief faces serious challenges.
Virginia Gewin
doi:10.1038/nj7194-560a
Upping student numbers and diversity p560
Undergraduate research awardees emphasize diversity.
Virginia Gewin
doi:10.1038/nj7194-560b
An impassive observation p560
An impassioned observer.
Aliza le Roux
doi:10.1038/nj7194-560c
Spotlight
Spotlight on Alabama
doi:10.1038/nj0211
Highlights
Highlight on Spain
doi:10.1038/nj0212
Futures
The Neanderthal correlation p562
A question of breeding.
Jeff Hecht
doi:10.1038/453562a
