Table of contents
Volume 453 Number 7191 pp1-132
(this content only available online) indicates content that is available online only
Editorials
California against cronyism p1
The scale of funds set to be spent by the state on stem-cell research necessitates strong governance.
doi:10.1038/453001a
A research menu p1
More spending on agricultural science is needed to help resolve the world's food crisis.
doi:10.1038/453001b
A place for everything p2
More researchers must record the latitude and longitude of their data.
doi:10.1038/453002a
Research Highlights
Cell biology: Casting anchor p4
doi:10.1038/453004a
Neurobiology: Pecking order p4
doi:10.1038/453004b
Human biology: Boy appétit p4
doi:10.1038/453004c
Chemical biology: Dope hope p4
doi:10.1038/453004d
Astronomy: Galactic beginnings p4
doi:10.1038/453004e
Animal behaviour: A reassuring tune p4
doi:10.1038/453004f
Molecular physics: Slicing the ice p5
doi:10.1038/453005a
Virology: Rubbish imitation p5
doi:10.1038/453005b
Atmospheric science: Jetting away p5
doi:10.1038/453005c
Neuroscience: Algal vision p5
doi:10.1038/453005d
News
Doctors accused of doing illegal stem-cell trials p6
Patients in Austria may have been misled.
Alison Abbott
doi:10.1038/453006a
US ocean-research projects in dire economic straits p7
Multiple marine projects under threat from cash squeeze.
Rex Dalton
doi:10.1038/453007a
Food crisis spurs research spending p8
Agricultural research comes in from the cold.
Declan Butler
doi:10.1038/453008a
Genetics bill cruises through Senate p9
Unanimous vote welcomed by personal genomics companies.
Meredith Wadman
doi:10.1038/453009a
Snapshot: Rodent round-up p9
It's been a good week for rat-catchers.
doi:10.1038/453009b
If you go down to the woods today ... p11
Eric Hand
doi:10.1038/453011a
Sidelines p12
Scribbles on the margins of science.
doi:10.1038/453012a
Programs promise to end PDF paper-chase p12
Software makes article control a virtual reality.
Rachel Courtland
doi:10.1038/453012b
Sediment cores reveal Antarctica's warmer past p13
Quirin Schiermeier
doi:10.1038/453013a
International consortium to tackle cancer genomes p15
doi:10.1038/453015a
A lift for Europe's satellites p15
doi:10.1038/453015b
Warming Antarctic waters begin to cool p15
doi:10.1038/453015c
UK government slammed for underfunding research p15
doi:10.1038/453015d
Creationists fail in bid to offer 'science' degrees p15
doi:10.1038/453015e
Artist cleared over possession of bacteria p15
doi:10.1038/453015f
Correction p15
doi:10.1038/453015g
Column
Party of OneDemonstrably wrong p16
Public–private demonstration projects are a good way to test technology in the field. But the driving force is often more political than scientific, argues David Goldston.
David Goldston
doi:10.1038/453016a
News Features
Stem cells: The 3-billion-dollar question p18
Can a state do what a country cannot, and transform the way stem-cell research is funded? Erika Check Hayden reports on the California Institute for Regenerative Medicine.
doi:10.1038/453018a
Physics: Quantum all the way p22
How does our classical world emerge from the counterintuitive principles of quantum theory? Can we even be sure that the world doesn't 'go quantum' when no one is watching? Philip Ball talks to the theorists and experimentalists trying to find out.
doi:10.1038/453022a
Correspondence
Biopiracy rules hinder conservation efforts p26
Valentí Rull & Teresa Vegas-Vilarrúbia
doi:10.1038/453026a
Biopiracy: conservationists have to rebuild lost trust p26
Mariana M. Vale, Maria Alice Alves & Stuart L. Pimm
doi:10.1038/453026b
Spain should implement a model that's known to work p26
Rodrigo J. Carbajo, José Luis Neira & Rosa Farràs
doi:10.1038/453026c
Spain: leading role of scientists is heartening p27
Pere Puigdomènech
doi:10.1038/453027a
Darwin–Wallace principle of natural selection p27
U. Kutschera
doi:10.1038/453027b
The status of science in Muslim nations p27
K. Razi Naqvi
doi:10.1038/453027c
Commentaries
Making the grade p28
International testing that is used to predict the grim future of US science and technology is being vastly misinterpreted, say Hal Salzman and Lindsay Lowell.
doi:10.1038/453028a
See also: Editor's summary
Science teaching must evolve p31
Evolutionary theory, study and knowledge moved on dramatically in the latter half of the twentieth century, but school teaching, curricula and teacher training are still in the primeval soup era, says Andrew Moore.
doi:10.1038/453031a
See also: Editor's summary
Books and Arts
Mix and mash-up p33
An experimental musician explores how technology has transformed our cut-and-paste culture.
Marc Weidenbaum reviews Sound Unbound: Sampling Digital Music and Culture
doi:10.1038/453033a
Exemplary epidemiology p34
Mark Woolhouse reviews Modeling Infectious Diseases in Humans and Animals by Matt J. Keeling & Pejman Rohani
doi:10.1038/453034a
Exhibition: Measure for measure p35
John D. Barrow reviews Beyond Measure: Conversations Across Art and Science
doi:10.1038/453035a
Exhibition: Changing expressions p36
Laura Spinney reviews Lovis Corinth (1858–1925): Between Impressionism and Expressionism
doi:10.1038/453036a
Exhibition: Etching the artist's mind p36
Colin Martin reviews Scribing the Soul
doi:10.1038/453036b
The Impressionists' bible p37
Ogden Rood's textbook explaining the science of optics and colour mixing triggered an unexpectedly vivid response from the radical artists of the 1880s.
Martin Kemp
doi:10.1038/453037a
In retrospect: When business became biology's plague p38
A 1920s best-seller about risky campus capitalism and early phage therapy still resonates today.
Thomas Häusler reviews Arrowsmith by Sinclair Lewis
doi:10.1038/453038a
Essay
Lifting the fog from the north p39
A purist approach to wavefunctions can resolve some of quantum theory's infamous murkiness.
Maximilian Schlosshauer
doi:10.1038/453039a
See also: Editor's summary
News and Views
Neuroscience: Hidden female talent p41
A male fruitfly serenades his female with a courtship song produced by vibrating one wing. The female also has the neuronal circuitry to generate a song of her own, but her brain tells her not to.
Jai Y. Yu & Barry J. Dickson
doi:10.1038/453041a
Electronics: The fourth element p42
Almost four decades since its existence was first proposed, a fourth basic circuit element joins the canonical three. The 'memristor' might herald a step-change in the march towards ever more powerful circuitry.
James M. Tour & Tao He
doi:10.1038/453042a
See also: Editor's summary
Climate change: Natural ups and downs p43
The effects of global warming over the coming decades will be modified by shorter-term climate variability. Finding ways to incorporate these variations will give us a better grip on what kind of climate change to expect.
Richard Wood
doi:10.1038/453043a
See also: Editor's summary
Quantum physics: The squeeze goes on p45
After 20 years of hard labour, squeezed states — light and matter whose quantum fluctuations have been arduously suppressed below standard levels of quantum noise — are coming of age and are ripe for application.
Eugene S. Polzik
doi:10.1038/453045a
Immunology: T cells hang in the balance p46
Equally important as the immune system's function in fighting invaders is its ability to tolerate self. But environmental toxins could shift the equilibrium between these activities one way or the other.
Emily A. Stevens & Christopher A. Bradfield
doi:10.1038/453046a
See also: Editor's summary
Networks: Teasing out the missing links p47
Focusing on the hierarchical structure inherent in social and biological networks might provide a smart way to find missing connections that are not revealed in the raw data — which could be useful in a range of contexts.
Sid Redner
doi:10.1038/453047a
See also: Editor's summary
Astrophysics: Rays from the dark p48
The origin of the cosmic rays that bombard Earth has troubled physicists for nigh on a century. Supernova remnants are a favoured source — but we should keep our minds open to alternatives.
Rainer Plaga
doi:10.1038/453048a
Obituary: John Wheeler (1911–2008) p50
Theoretical physicist, inspired and inspiring teacher.
P. James E. Peebles & William G. Unruh
doi:10.1038/453050a
See also: Editor's summary
Articles
Rapid leukocyte migration by integrin-independent flowing and squeezing p51
Tim Lämmermann, Bernhard L. Bader, Susan J. Monkley, Tim Worbs, Roland Wedlich-Söldner, Karin Hirsch, Markus Keller, Reinhold Förster, David R. Critchley, Reinhard Fässler & Michael Sixt
doi:10.1038/nature06887
Abstract | Full Text | PDF (1,330K) | Supplementary information
See also: Editor's summary
Mapping and sequencing of structural variation from eight human genomes p56
Jeffrey M. Kidd, Gregory M. Cooper, William F. Donahue, Hillary S. Hayden, Nick Sampas, Tina Graves, Nancy Hansen, Brian Teague, Can Alkan, Francesca Antonacci, Eric Haugen, Troy Zerr, N. Alice Yamada, Peter Tsang, Tera L. Newman, Eray Tüzün, Ze Cheng, Heather M. Ebling, Nadeem Tusneem, Robert David, Will Gillett, Karen A. Phelps, Molly Weaver, David Saranga, Adrianne Brand, Wei Tao, Erik Gustafson, Kevin McKernan, Lin Chen, Maika Malig, Joshua D. Smith, Joshua M. Korn, Steven A. McCarroll, David A. Altshuler, Daniel A. Peiffer, Michael Dorschner, John Stamatoyannopoulos, David Schwartz, Deborah A. Nickerson, James C. Mullikin, Richard K. Wilson, Laurakay Bruhn, Maynard V. Olson, Rajinder Kaul, Douglas R. Smith & Evan E. Eichler
doi:10.1038/nature06862
Abstract | Full Text | PDF (716K) | Supplementary information
See also: Editor's summary
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor p65
Francisco J. Quintana, Alexandre S. Basso, Antonio H. Iglesias, Thomas Korn, Mauricio F. Farez, Estelle Bettelli, Mario Caccamo, Mohamed Oukka & Howard L. Weiner
doi:10.1038/nature06880
Abstract | Full Text | PDF (826K) | Supplementary information
See also: Editor's summary | News and Views by Stevens & Bradfield
Letters
The sculpting of Jupiter's gossamer rings by its shadow p72
Douglas P. Hamilton & Harald Krüger
doi:10.1038/nature06886
First paragraph | Full Text | PDF (1,243K)
See also: Editor's summary
Phase-slip-induced dissipation in an atomic Bose–Hubbard system p76
D. McKay, M. White, M. Pasienski & B. DeMarco
doi:10.1038/nature06920
First paragraph | Full Text | PDF (598K)
The missing memristor found p80
Dmitri B. Strukov, Gregory S. Snider, Duncan R. Stewart & R. Stanley Williams
doi:10.1038/nature06932
First paragraph | Full Text | PDF (323K)
See also: Editor's summary | News and Views by Tour & He
Advancing decadal-scale climate prediction in the North Atlantic sector p84
N. S. Keenlyside, M. Latif, J. Jungclaus, L. Kornblueh & E. Roeckner
doi:10.1038/nature06921
First paragraph | Full Text | PDF (600K) | Supplementary information
See also: Editor's summary | News and Views by Wood
Origin of a 'Southern Hemisphere' geochemical signature in the Arctic upper mantle p89
Steven L. Goldstein, Gad Soffer, Charles H. Langmuir, Kerstin A. Lehnert, David W. Graham & Peter J. Michael
doi:10.1038/nature06919
First paragraph | Full Text | PDF (584K) | Supplementary information
Hydatellaceae are water lilies with gymnospermous tendencies p94
William E. Friedman
doi:10.1038/nature06733
First paragraph | Full Text | PDF (1,011K) | Supplementary information
See also: Editor's summary
Hierarchical structure and the prediction of missing links in networks p98
Aaron Clauset, Cristopher Moore & M. E. J. Newman
doi:10.1038/nature06830
First paragraph | Full Text | PDF (259K) | Supplementary information
See also: Editor's summary | News and Views by Redner
Melanopsin cells are the principal conduits for rod–cone input to non-image-forming vision p102
Ali D. Güler, Jennifer L. Ecker, Gurprit S. Lall, Shafiqul Haq, Cara M. Altimus, Hsi-Wen Liao, Alun R. Barnard, Hugh Cahill, Tudor C. Badea, Haiqing Zhao, Mark W. Hankins, David M. Berson, Robert J. Lucas, King-Wai Yau & Samer Hattar
doi:10.1038/nature06829
First paragraph | Full Text | PDF (1,246K) | Supplementary information
See also: Editor's summary
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins p106
Marc Veldhoen, Keiji Hirota, Astrid M. Westendorf, Jan Buer, Laure Dumoutier, Jean-Christophe Renauld & Brigitta Stockinger
doi:10.1038/nature06881
First paragraph | Full Text | PDF (502K) | Supplementary information
See also: Editor's summary | News and Views by Stevens & Bradfield
BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros p110
Charles G. Mullighan, Christopher B. Miller, Ina Radtke, Letha A. Phillips, James Dalton, Jing Ma, Deborah White, Timothy P. Hughes, Michelle M. Le Beau, Ching-Hon Pui, Mary V. Relling, Sheila A. Shurtleff & James R. Downing
doi:10.1038/nature06866
First paragraph | Full Text | PDF (459K) | Supplementary information
See also: Editor's summary
Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions p115
Stavroula Mili, Konstadinos Moissoglu & Ian G. Macara
doi:10.1038/nature06888
First paragraph | Full Text | PDF (2,004K) | Supplementary information
See also: Editor's summary
Life without RNase P p120
Lennart Randau, Imke Schröder & Dieter Söll
doi:10.1038/nature06833
First paragraph | Full Text | PDF (861K) | Supplementary information
See also: Editor's summary
Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS p124
Raz Zarivach, Wanyin Deng, Marija Vuckovic, Heather B. Felise, Hai V. Nguyen, Samuel I. Miller, B. Brett Finlay & Natalie C. J. Strynadka
doi:10.1038/nature06832
First paragraph | Full Text | PDF (983K) | Supplementary information
Corrigendum
Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila p128
Cathy Haag-Liautard, Mark Dorris, Xulio Maside, Steven Macaskill, Daniel L. Halligan, David Houle, Brian Charlesworth & Peter D. Keightley
doi:10.1038/nature06946
Naturejobs
ProspectProspects p129
US National Postdoctoral Association campaigns for stipend boost.
Gene Russo
doi:10.1038/nj7191-129a
Career View
Eaton E. Lattman, chief executive and executive director of the Hauptman-Woodward Medical Research Institute, Buffalo, New York p130
Crystallographer takes over at Buffalo's Hauptman-Woodward Medical Research Institute.
Virginia Gewin
doi:10.1038/nj7191-130a
Crossing borders p130
Training programme links Stockholm and New York.
Paul Smaglik
doi:10.1038/nj7191-130b
Meeting our targets p130
Evaluating the metrics of my own 'success'.
Amanda Goh
doi:10.1038/nj7191-130c
Highlights
Opportunities: The National Institutes of Health
doi:10.1038/nj0206
Futures
Build your own time machine p132
It's a unique set of experiences.
Igor Teper
doi:10.1038/453132a
