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Nature 452, 1007-1011 (13 April 2008) | doi:10.1038/nature06861;
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Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels
From worm to man, many odorant signals are perceived by the binding of volatile ligands to odorant receptors that belong to the G-protein-coupled receptor (GPCR) family. They couple to heterotrimeric G-proteins, most of which induce cAMP production.
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