Table of contents
Volume 452 Number 7188 pp665-780
(this content only available online) indicates content that is available online only
Editorials
The path to productive partnerships p665
Research funders and institutions do too little to sustain the collaborations that they encourage.
doi:10.1038/452665a
Defining 'natural' p665
Visceral reactions to an act should not distract from the real ethical issues.
doi:10.1038/452665b
Ready or not p666
Transparency and honesty are essential if the genetic-testing industry is to live up to its potential.
doi:10.1038/452666a
News
FDA to vet embryonic stem cells' safety p670
US agency holds first public hearings to assess therapies.
Monya Baker
doi:10.1038/452670a
Advanced biofuels face an uncertain future p670
Aggressive US mandate may do more harm than good.
Jeff Tollefson
doi:10.1038/452670b
Chemical weapons agency shifts focus p671
Diplomats ponder the dangers posed by the drug industry.
Daniel Cressey
doi:10.1038/452671a
Sidelines p672
Scribbles on the margins of science.
doi:10.1038/452672a
Gertrude versus Goliath p672
Octogenarian takes on the electronics giants over LED patents.
Geoff Brumfiel
doi:10.1038/452672b
The fraudster returns... p672
Hans Gottinger is back on the scientific scene.
Alison Abbott
doi:10.1038/452672c
Q&A: Bill Foster p673
At the age of 19, Bill Foster started a theatrical lighting company that now provides equipment for rock concerts and Super Bowl shows. A PhD at Harvard led him to Fermilab in Batavia, Illinois, where he built electronics for a quark detector. In an election win last month, he entered Congress as a Democratic representative for Illinois. Eric Hand caught up with him.
Eric Hand
doi:10.1038/452673a
Poll results: look who's doping p674
In January, Nature launched an informal survey into readers' use of cognition-enhancing drugs. Brendan Maher has waded through the results and found large-scale use and a mix of attitudes towards the drugs.
Brendan Maher
doi:10.1038/452674a
Radio sweat gland — 90 GHz p676
The perils of perspiration.
Philip Ball
doi:10.1038/452676a
UK satellite firm acquired by European space giant p677
doi:10.1038/452677a
Brucellosis fears hamper Yellowstone bison plans p677
doi:10.1038/452677b
Tanzania takes steps to save ancient human prints p677
doi:10.1038/452677c
Pfizer fails to gain access to peer-review files p677
doi:10.1038/452677d
Environment agency reopens doors to libraries p677
doi:10.1038/452677e
An insight into amber p677
doi:10.1038/452677f
Correction p677
doi:10.1038/452677g
News Features
Evolution: Scandal! Sex-starved and still surviving p678
Some creatures have what it takes to survive long dry spells. How they do this may be revealed in their genes, reports Erika Check Hayden.
doi:10.1038/452678a
Collaborations: With all good intentions p682
Collaborations spawn fresh ideas and boost productivity — most of the time. Heidi Ledford examines what happens when a working relationship breaks down, and asks how to avoid it.
doi:10.1038/452682a
Correspondence
CropLife still committed to assessment's original aims p685
Howard Minigh
doi:10.1038/452685a
Italy must invest more in science and technology p685
Ivano Bertini, Silvio Garattini & Rino Rappuoli
doi:10.1038/452685b
Cleaning up the final phase of the fossil-fuel industry p685
Steve Larter
doi:10.1038/452685c
Commentary
Collaborations: Investigating international misconduct p686
The rise in cross-border collaborations is making it more difficult to police misconduct. Christine Boesz and Nigel Lloyd argue for a framework to examine allegations and hold researchers accountable.
doi:10.1038/452686a
Spring Books
Shaking the foundations of archaeology p689
Did earthquakes trigger the collapse of ancient civilizations?
Andrew Robinson reviews Apocalypse: Earthquakes, Archaeology and the Wrath of God by Amos Nur & Dawn Burgess
doi:10.1038/452689a
New in Paperback p689
doi:10.1038/452689b
Brave new bioethics p690
Eugenie Scott reviews Life As It Is: Biology for the Public Sphere by William F. Loomis
doi:10.1038/452690a
Engines of life p691
Tim Lenton reviews Energy in Nature and Society by Vaclav Smil
doi:10.1038/452691a
Biology from the bottom up p692
Steven Benner reviews What Is Life? Investigating the Nature of Life in the Age of Synthetic Biology by Ed Regis
doi:10.1038/452692a
Bottling the nuclear demon p694
Martin van Creveld reviews Why Nuclear Disarmament Matters by Hans Blix and On Nuclear Terrorism by Michael Levi
doi:10.1038/452694a
How music speaks to us p695
David Poeppel & Elika Bergelson review Music, Language, and the Brain by Aniruddh D. Patel
doi:10.1038/452695a
Catching a ride on sunshine p696
Stuart Clark reviews Solar Sails: A Novel Approach to Interplanetary Travel by Giovanni Vulpetti, Les Johnson & Gregory L. Matloff
doi:10.1038/452696a
Imaging the unseen p697
Felice Frankel reviews Six Stories from the End of Representation: Images in Painting, Photography, Astronomy, Microscopy, Particle Physics, and Quantum Mechanics, 1980–2000 by James Elkins
doi:10.1038/452697a
Essay
Rise of the digital machine p699
Genomes and language suggest that biological and social complexity emerge from how information is used, argues Mark Pagel, not from how much of it there is.
Mark Pagel
doi:10.1038/452699a
News and Views
Atmospheric chemistry: Are plant emissions green? p701
Hydrocarbon emissions from living vegetation are thought to be harmful to the atmosphere. But the latest study suggests that the negative impact of these emissions in pristine environments is less than expected.
Alex Guenther
doi:10.1038/452701a
See also: Editor's summary
Immunology: Blood lines redrawn p702
The generation of blood cells is a complex affair. As the culmination of several years of study by various investigators, the latest research will necessitate revision of textbook accounts of the process.
Thomas Graf
doi:10.1038/452702a
See also: Editor's summary
Materials science: Strong teeth, strong seeds p703
A full account of the relationships between tooth form, structure and function remains out of reach. Viewing teeth from an engineering materials perspective offers a way to help crack the problem.
Peter Ungar
doi:10.1038/452703a
50 & 100 Years Ago p704
doi:10.1038/452704a
Quantum physics: Observations turn up the heat p705
The idea that observers can influence what they observe has a history that stretches back beyond quantum physics. That we can affect how a system heats up and cools down simply by probing it is a new twist.
Kimberly R. Chapin & Marlan O. Scully
doi:10.1038/452705a
See also: Editor's summary
Cell biology: Porter and sorter p706
Clathrin is a protein familiar for its ability to import material into cells. But it also seems to mediate another crucial process — helping newly made proteins to pick the right destination on the cell surface.
Michael G. Roth
doi:10.1038/452706a
See also: Editor's summary
Neurodegeneration: A question of balance p707
When a disease-associated gene is mutated, is the cellular activity of its protein product enhanced or reduced? For at least one neurodegenerative disease, spinocerebellar ataxia 1, the answer seems to be both.
Leslie Michels Thompson
doi:10.1038/452707a
See also: Editor's summary
News and Views Q&A
Cell biology: SUMO p709
A protein called small ubiquitin-related modifier (SUMO) can be coupled to other proteins to control their function. This SUMOylation has been implicated in the regulation of a host of cellular processes, and is essential for the health, and even the survival, of most organisms.
Erik Meulmeester & Frauke Melchior
doi:10.1038/452709a
See also: Editor's summary
Articles
Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1 p713
Janghoo Lim, Juan Crespo-Barreto, Paymaan Jafar-Nejad, Aaron B. Bowman, Ronald Richman, David E. Hill, Harry T. Orr & Huda Y. Zoghbi
doi:10.1038/nature06731
Abstract | Full Text | PDF (728K) | Supplementary information
See also: Editor's summary | News and Views by Thompson
Clathrin is a key regulator of basolateral polarity p719
Sylvie Deborde, Emilie Perret, Diego Gravotta, Ami Deora, Susana Salvarezza, Ryan Schreiner & Enrique Rodriguez-Boulan
doi:10.1038/nature06828
Abstract | Full Text | PDF (1,142K) | Supplementary information
See also: Editor's summary | News and Views by Roth
Letters
Thermodynamic control by frequent quantum measurements p724
Noam Erez, Goren Gordon, Mathias Nest & Gershon Kurizki
doi:10.1038/nature06873
First paragraph | Full Text | PDF (385K) | Supplementary information
See also: Editor's summary | News and Views by Chapin & Scully
Microscopic theory of the extraordinary optical transmission p728
Haitao Liu & Philippe Lalanne
doi:10.1038/nature06762
First paragraph | Full Text | PDF (463K) | Supplementary information
See also: Editor's summary
Improper ferroelectricity in perovskite oxide artificial superlattices p732
Eric Bousquet, Matthew Dawber, Nicolas Stucki, Céline Lichtensteiger, Patrick Hermet, Stefano Gariglio, Jean-Marc Triscone & Philippe Ghosez
doi:10.1038/nature06817
First paragraph | Full Text | PDF (647K) | Supplementary information
See also: Editor's summary
Atmospheric oxidation capacity sustained by a tropical forest p737
J. Lelieveld, T. M. Butler, J. N. Crowley, T. J. Dillon, H. Fischer, L. Ganzeveld, H. Harder, M. G. Lawrence, M. Martinez, D. Taraborrelli & J. Williams
doi:10.1038/nature06870
First paragraph | Full Text | PDF (676K) | Supplementary information
See also: Editor's summary | News and Views by Guenther
SAR11 marine bacteria require exogenous reduced sulphur for growth p741
H. James Tripp, Joshua B. Kitner, Michael S. Schwalbach, John W. H. Dacey, Larry J. Wilhelm & Stephen J. Giovannoni
doi:10.1038/nature06776
First paragraph | Full Text | PDF (247K) | Supplementary information
See also: Editor's summary
Broad phylogenomic sampling improves resolution of the animal tree of life p745
Casey W. Dunn, Andreas Hejnol, David Q. Matus, Kevin Pang, William E. Browne, Stephen A. Smith, Elaine Seaver, Greg W. Rouse, Matthias Obst, Gregory D. Edgecombe, Martin V. Sørensen, Steven H. D. Haddock, Andreas Schmidt-Rhaesa, Akiko Okusu, Reinhardt Møbjerg Kristensen, Ward C. Wheeler, Mark Q. Martindale & Gonzalo Giribet
doi:10.1038/nature06614
First paragraph | Full Text | PDF (381K) | Supplementary information
See also: Editor's summary
Estimating the impact of school closure on influenza transmission from Sentinel data p750
Simon Cauchemez, Alain-Jacques Valleron, Pierre-Yves Boëlle, Antoine Flahault & Neil M. Ferguson
doi:10.1038/nature06732
First paragraph | Full Text | PDF (463K) | Supplementary information
See also: Editor's summary
A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism p755
Michael Groll, Barbara Schellenberg, André S. Bachmann, Crystal R. Archer, Robert Huber, Tracy K. Powell, Steven Lindow, Markus Kaiser & Robert Dudler
doi:10.1038/nature06782
First paragraph | Full Text | PDF (571K) | Supplementary information
See also: Editor's summary
Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons p759
Takako Makita, Henry M. Sucov, Cheryl E. Gariepy, Masashi Yanagisawa & David D. Ginty
doi:10.1038/nature06859
First paragraph | Full Text | PDF (5,023K) | Supplementary information
The earliest thymic progenitors for T cells possess myeloid lineage potential p764
J. Jeremiah Bell & Avinash Bhandoola
doi:10.1038/nature06840
First paragraph | Full Text | PDF (558K) | Supplementary information
See also: Editor's summary | News and Views by Graf
Adult T-cell progenitors retain myeloid potential p768
Haruka Wada, Kyoko Masuda, Rumi Satoh, Kiyokazu Kakugawa, Tomokatsu Ikawa, Yoshimoto Katsura & Hiroshi Kawamoto
doi:10.1038/nature06839
First paragraph | Full Text | PDF (898K) | Supplementary information
See also: Editor's summary | News and Views by Graf
Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome p773
Joshua D. Milner, Jason M. Brenchley, Arian Laurence, Alexandra F. Freeman, Brenna J. Hill, Kevin M. Elias, Yuka Kanno, Christine Spalding, Houda Z. Elloumi, Michelle L. Paulson, Joie Davis, Amy Hsu, Ava I. Asher, John O'Shea, Steven M. Holland, William E. Paul & Daniel C. Douek
doi:10.1038/nature06764
First paragraph | Full Text | PDF (393K) | Supplementary information
Naturejobs
ProspectProspects p777
The quality of researcher jobs, and not just the quantity, deserves further scrutiny.
Gene Russo
doi:10.1038/nj7188-777a
Career View
Billie Turner, Gilbert F. White chair in environment and society, School of Geographical Sciences, Arizona State University, Tempe, Arizona p778
'Sustainability' pioneer joins Arizona State University.
Virginia Gewin
doi:10.1038/nj7188-778a
Focus on health disparities p778
The NIH adds genetics of health disparities centre to its Bethesda campus.
Paul Smaglik
doi:10.1038/nj7188-778b
The very hungry postdoc p778
Gauging publication risk and reward.
Jon Yearsley
doi:10.1038/nj7188-778c
Highlights
Highlight:Austria
doi:10.1038/nj0203