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Nature 452, 541-542 (3 April 2008) | doi:10.1038/452541a; Published online 2 April 2008

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Drug resistance: The fight against fungi

André Goffeau1

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Although several drugs are available to combat often-deadly fungal infections, many of these pathogens have acquired multidrug resistance. Discerning how they have achieved this could help us hit back.

When we think of infectious agents, it is viruses and bacteria that first come to mind — fungi do not sound especially threatening. But opportunistic fungal infection is an emerging problem, particularly for immunocompromised patients such as those with AIDS and cancer, or those who have undergone organ transplants.

  1. André Goffeau is at the Institut des Sciences de la Vie, Université catholique de Louvain, Croix du Sud 5/15, 1349 Louvain-la-Neuve, Belgium.
    Email: andre.goffeau@scarlet.be