TY - JOUR AU - Edwards, A. O. TI - Complement factor H polymorphism and age-related macular degeneration JA - Science PY - 2005/// VL - 308 SP - 421 EP - 424 PB - Nature Publishing Group M3 - 10.1126/science.1110189 N1 - 10.1126/science.1110189 UR - http://dx.doi.org/10.1126/science.1110189 ER - TY - JOUR AU - Haines, J. L. TI - Complement factor H variant increases the risk of age-related macular degeneration JA - Science PY - 2005/// VL - 308 SP - 419 EP - 421 PB - Nature Publishing Group M3 - 10.1126/science.1110359 N1 - 10.1126/science.1110359 UR - http://dx.doi.org/10.1126/science.1110359 ER - TY - JOUR AU - Klein, R. J. TI - Complement factor H polymorphism in age-related macular degeneration JA - Science PY - 2005/// VL - 308 SP - 385 EP - 389 PB - Nature Publishing Group M3 - 10.1126/science.1109557 N1 - 10.1126/science.1109557 UR - http://dx.doi.org/10.1126/science.1109557 ER - TY - JOUR AU - Sladek, R. TI - A genome-wide association study identifies novel risk loci for type 2 diabetes JA - Nature PY - 2007/// VL - 445 SP - 881 EP - 885 PB - Nature Publishing Group M3 - 10.1038/nature05616 N1 - 10.1038/nature05616 UR - http://dx.doi.org/10.1038/nature05616 ER - TY - JOUR AU - Frayling, T. M. TI - A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity JA - Science PY - 2007/// VL - 316 SP - 889 EP - 894 PB - Nature Publishing Group M3 - 10.1126/science.1141634 N1 - 10.1126/science.1141634 UR - http://dx.doi.org/10.1126/science.1141634 ER - TY - JOUR AU - Strittmatter, W. J. TI - Apolipoprotein E: high-avidity binding to [bgr]-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease JA - Proc. Natl Acad. Sci. USA PY - 1993/// VL - 90 SP - 1977 EP - 1981 PB - Nature Publishing Group M3 - 10.1073/pnas.90.5.1977 N1 - 10.1073/pnas.90.5.1977 UR - http://dx.doi.org/10.1073/pnas.90.5.1977 ER - TY - JOUR AU - Brem, R. B. AU - Yvert, G. AU - Clinton, R. AU - Kruglyak, L. TI - Genetic dissection of transcriptional regulation in budding yeast JA - Science PY - 2002/// VL - 296 SP - 752 EP - 755 PB - Nature Publishing Group M3 - 10.1126/SCIENCE.1069516 N1 - 10.1126/SCIENCE.1069516 UR - http://dx.doi.org/10.1126/SCIENCE.1069516 ER - TY - JOUR AU - Bystrykh, L. TI - Uncovering regulatory pathways that affect hematopoietic stem cell function using /`genetical genomics/' JA - Nature Genet. PY - 2005/// VL - 37 SP - 225 EP - 232 PB - Nature Publishing Group M3 - 10.1038/ng1497 N1 - 10.1038/ng1497 UR - http://dx.doi.org/10.1038/ng1497 ER - TY - JOUR AU - Chesler, E. J. TI - Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function JA - Nature Genet. PY - 2005/// VL - 37 SP - 233 EP - 242 PB - Nature Publishing Group M3 - 10.1038/ng1518 N1 - 10.1038/ng1518 UR - http://dx.doi.org/10.1038/ng1518 ER - TY - JOUR AU - Monks, S. A. TI - Genetic inheritance of gene expression in human cell lines JA - Am. J. Hum. Genet. PY - 2004/// VL - 75 SP - 1094 EP - 1105 PB - Nature Publishing Group M3 - 10.1086/426461 N1 - 10.1086/426461 UR - http://dx.doi.org/10.1086/426461 ER - TY - JOUR AU - Schadt, E. E. TI - An integrative genomics approach to infer causal associations between gene expression and disease JA - Nature Genet. PY - 2005/// VL - 37 SP - 710 EP - 717 PB - Nature Publishing Group M3 - 10.1038/ng1589 N1 - 10.1038/ng1589 UR - http://dx.doi.org/10.1038/ng1589 ER - TY - JOUR AU - Schadt, E. E. TI - Genetics of gene expression surveyed in maize, mouse and man JA - Nature PY - 2003/// VL - 422 SP - 297 EP - 302 PB - Nature Publishing Group M3 - 10.1038/nature01434 N1 - 10.1038/nature01434 UR - http://dx.doi.org/10.1038/nature01434 ER - TY - JOUR AU - Hartwell, L. H. AU - Hopfield, J. J. AU - Leibler, S. AU - Murray, A. W. TI - From molecular to modular cell biology JA - Nature PY - 1999/// VL - 402 SP - C47 EP - C52 PB - Nature Publishing Group M3 - 10.1038/35011540 N1 - 10.1038/35011540 UR - http://dx.doi.org/10.1038/35011540 ER - TY - JOUR AU - Schadt, E. E. AU - Sachs, A. AU - Friend, S. TI - Embracing complexity, inching closer to reality JA - Sci. STKE PY - 2005/// VL - 2005 SP - pe40 PB - Nature Publishing Group M3 - 10.1126/stke.2952005pe40 N1 - 10.1126/stke.2952005pe40 UR - http://dx.doi.org/10.1126/stke.2952005pe40 ER - TY - JOUR AU - Paigen, B. AU - Albee, D. AU - Holmes, P. A. AU - Mitchell, D. TI - Genetic analysis of murine strains C57BL/6J and C3H/HeJ to confirm the map position of Ath-1, a gene determining atherosclerosis susceptibility JA - Biochem. Genet. PY - 1987/// VL - 25 SP - 501 EP - 511 PB - Nature Publishing Group M3 - 10.1007/BF00554352 N1 - 10.1007/BF00554352 UR - http://dx.doi.org/10.1007/BF00554352 ER - TY - JOUR AU - Yang, X. TI - Tissue-specific expression and regulation of sexually dimorphic genes in mice JA - Genome Res. PY - 2006/// VL - 16 SP - 995 EP - 1004 PB - Nature Publishing Group M3 - 10.1101/gr.5217506 N1 - 10.1101/gr.5217506 UR - http://dx.doi.org/10.1101/gr.5217506 ER - TY - JOUR AU - Wang, S. TI - Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity JA - PLoS Genet. PY - 2006/// VL - 2 SP - e15 PB - Nature Publishing Group M3 - 10.1371/journal.pgen.0020015 N1 - 10.1371/journal.pgen.0020015 UR - http://dx.doi.org/10.1371/journal.pgen.0020015 ER - TY - JOUR AU - Paigen, B. TI - Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice JA - Proc. Natl Acad. Sci. USA PY - 1987/// VL - 84 SP - 3763 EP - 3767 PB - Nature Publishing Group ER - TY - JOUR AU - Castellani, L. W. AU - Goto, A. M. AU - Lusis, A. J. TI - Studies with apolipoprotein A-II transgenic mice indicate a role for HDLs in adiposity and insulin resistance JA - Diabetes PY - 2001/// VL - 50 SP - 643 EP - 651 PB - Nature Publishing Group M3 - 10.2337/diabetes.50.3.643 N1 - 10.2337/diabetes.50.3.643 UR - http://dx.doi.org/10.2337/diabetes.50.3.643 ER - TY - JOUR AU - Wang, X. AU - Korstanje, R. AU - Higgins, D. AU - Paigen, B. TI - Haplotype analysis in multiple crosses to identify a QTL gene JA - Genome Res. PY - 2004/// VL - 14 SP - 1767 EP - 1772 PB - Nature Publishing Group M3 - 10.1101/gr.2668204 N1 - 10.1101/gr.2668204 UR - http://dx.doi.org/10.1101/gr.2668204 ER - TY - JOUR AU - Wang, X. TI - Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility JA - Nature Genet. PY - 2005/// VL - 37 SP - 365 EP - 372 PB - Nature Publishing Group M3 - 10.1038/ng1524 N1 - 10.1038/ng1524 UR - http://dx.doi.org/10.1038/ng1524 ER - TY - JOUR AU - Warden, C. H. AU - Hedrick, C. C. AU - Qiao, J. H. AU - Castellani, L. W. AU - Lusis, A. J. TI - Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II JA - Science PY - 1993/// VL - 261 SP - 469 EP - 472 PB - Nature Publishing Group M3 - 10.1126/science.8332912 N1 - 10.1126/science.8332912 UR - http://dx.doi.org/10.1126/science.8332912 ER - TY - JOUR AU - Welch, C. L. TI - Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain JA - Physiol. Genomics PY - 2004/// VL - 17 SP - 48 EP - 59 PB - Nature Publishing Group M3 - 10.1152/physiolgenomics.00124.2003 N1 - 10.1152/physiolgenomics.00124.2003 UR - http://dx.doi.org/10.1152/physiolgenomics.00124.2003 ER - TY - JOUR AU - Doolittle, M. H. AU - LeBoeuf, R. C. AU - Warden, C. H. AU - Bee, L. M. AU - Lusis, A. J. TI - A polymorphism affecting apolipoprotein A-II translational efficiency determines high density lipoprotein size and composition JA - J. Biol. Chem. PY - 1990/// VL - 265 SP - 16380 EP - 16388 PB - Nature Publishing Group ER - TY - JOUR AU - Pajukanta, P. TI - Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1) JA - Nature Genet. PY - 2004/// VL - 36 SP - 371 EP - 376 PB - Nature Publishing Group M3 - 10.1038/ng1320 N1 - 10.1038/ng1320 UR - http://dx.doi.org/10.1038/ng1320 ER - TY - JOUR AU - Babinska, A. TI - F11-receptor (F11R/JAM) mediates platelet adhesion to endothelial cells: role in inflammatory thrombosis JA - Thromb. Haemost. PY - 2002/// VL - 88 SP - 843 EP - 850 PB - Nature Publishing Group ER - TY - JOUR AU - Huertas-Vazquez, A. TI - Familial combined hyperlipidemia in Mexicans: association with upstream transcription factor 1 and linkage on chromosome 16q24.1 JA - Arterioscler. Thromb. Vasc. Biol. PY - 2005/// VL - 25 SP - 1985 EP - 1991 PB - Nature Publishing Group ER - TY - JOUR AU - Ezzahiri, R. TI - Chlamydia pneumoniae infections augment atherosclerotic lesion formation: a role for serum amyloid P JA - APMIS PY - 2006/// VL - 114 SP - 117 EP - 126 PB - Nature Publishing Group M3 - 10.1111/j.1600-0463.2006.apm_205.x N1 - 10.1111/j.1600-0463.2006.apm_205.x UR - http://dx.doi.org/10.1111/j.1600-0463.2006.apm_205.x ER - TY - JOUR AU - Adams, L. D. AU - Geary, R. L. AU - Li, J. AU - Rossini, A. AU - Schwartz, S. M. TI - Expression profiling identifies smooth muscle cell diversity within human intima and plaque fibrous cap: loss of RGS5 distinguishes the cap JA - Arterioscler. Thromb. Vasc. Biol. PY - 2006/// VL - 26 SP - 319 EP - 325 PB - Nature Publishing Group M3 - 10.1161/01.ATV.0000196647.45718.d6 N1 - 10.1161/01.ATV.0000196647.45718.d6 UR - http://dx.doi.org/10.1161/01.ATV.0000196647.45718.d6 ER - TY - JOUR AU - Chang, Y. P. TI - Multiple genes for essential-hypertension susceptibility on chromosome 1q JA - Am. J. Hum. Genet. PY - 2007/// VL - 80 SP - 253 EP - 264 PB - Nature Publishing Group M3 - 10.1086/510918 N1 - 10.1086/510918 UR - http://dx.doi.org/10.1086/510918 ER - TY - JOUR AU - Mehrabian, M. TI - Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits JA - Nature Genet. PY - 2005/// VL - 37 SP - 1224 EP - 1233 PB - Nature Publishing Group M3 - 10.1038/ng1619 N1 - 10.1038/ng1619 UR - http://dx.doi.org/10.1038/ng1619 ER - TY - JOUR AU - Austyn, J. M. AU - Gordon, S. TI - F4/80, a monoclonal antibody directed specifically against the mouse macrophage JA - Eur. J. Immunol. PY - 1981/// VL - 11 SP - 805 EP - 815 PB - Nature Publishing Group M3 - 10.1002/eji.1830111013 N1 - 10.1002/eji.1830111013 UR - http://dx.doi.org/10.1002/eji.1830111013 ER - TY - JOUR AU - Ramprasad, M. P. AU - Terpstra, V. AU - Kondratenko, N. AU - Quehenberger, O. AU - Steinberg, D. TI - Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein JA - Proc. Natl Acad. Sci. USA PY - 1996/// VL - 93 SP - 14833 EP - 14838 PB - Nature Publishing Group M3 - 10.1073/pnas.93.25.14833 N1 - 10.1073/pnas.93.25.14833 UR - http://dx.doi.org/10.1073/pnas.93.25.14833 ER - TY - JOUR AU - Wright, S. D. AU - Ramos, R. A. AU - Tobias, P. S. AU - Ulevitch, R. J. AU - Mathison, J. C. TI - CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein JA - Science PY - 1990/// VL - 249 SP - 1431 EP - 1433 PB - Nature Publishing Group M3 - 10.1126/science.1698311 N1 - 10.1126/science.1698311 UR - http://dx.doi.org/10.1126/science.1698311 ER - TY - JOUR AU - Kubota, N. TI - PPAR[ggr] mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance JA - Mol. Cell PY - 1999/// VL - 4 SP - 597 EP - 609 PB - Nature Publishing Group M3 - 10.1016/S1097-2765(00)80210-5 N1 - 10.1016/S1097-2765(00)80210-5 UR - http://dx.doi.org/10.1016/S1097-2765(00)80210-5 ER - TY - JOUR AU - Hu, Y. AU - Liu, W. AU - Huang, R. AU - Zhang, X. TI - A systematic review and meta-analysis of the relationship between lipoprotein lipase Asn291Ser variant and diseases JA - J. Lipid Res. PY - 2006/// VL - 47 SP - 1908 EP - 1914 PB - Nature Publishing Group M3 - 10.1194/jlr.M600108-JLR200 N1 - 10.1194/jlr.M600108-JLR200 UR - http://dx.doi.org/10.1194/jlr.M600108-JLR200 ER - TY - JOUR AU - Preiss-Landl, K. AU - Zimmermann, R. AU - Hammerle, G. AU - Zechner, R. TI - Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism JA - Curr. Opin. Lipidol. PY - 2002/// VL - 13 SP - 471 EP - 481 PB - Nature Publishing Group M3 - 10.1097/00041433-200210000-00002 N1 - 10.1097/00041433-200210000-00002 UR - http://dx.doi.org/10.1097/00041433-200210000-00002 ER - TY - JOUR AU - Yost, T. J. AU - Jensen, D. R. AU - Eckel, R. H. TI - Tissue-specific lipoprotein lipase: relationships to body composition and body fat distribution in normal weight humans JA - Obes. Res. PY - 1993/// VL - 1 SP - 1 EP - 4 PB - Nature Publishing Group ER - TY - JOUR AU - Liobikas, J. TI - Expression and purification of the mitochondrial serine protease LACTB as an N-terminal GST fusion protein in Escherichia coli JA - Protein Expr. Purif. PY - 2006/// VL - 45 SP - 335 EP - 342 PB - Nature Publishing Group M3 - 10.1016/j.pep.2005.08.006 N1 - 10.1016/j.pep.2005.08.006 UR - http://dx.doi.org/10.1016/j.pep.2005.08.006 ER - TY - JOUR AU - Smith, T. S. TI - Identification, genomic organization, and mRNA expression of LACTB, encoding a serine [bgr]-lactamase-like protein with an amino-terminal transmembrane domain JA - Genomics PY - 2001/// VL - 78 SP - 12 EP - 14 PB - Nature Publishing Group M3 - 10.1006/geno.2001.6643 N1 - 10.1006/geno.2001.6643 UR - http://dx.doi.org/10.1006/geno.2001.6643 ER - TY - JOUR AU - Jacobs, C. TI - Life in the balance: cell walls and antibiotic resistance JA - Science PY - 1997/// VL - 278 SP - 1731 EP - 1732 PB - Nature Publishing Group M3 - 10.1126/science.278.5344.1731b N1 - 10.1126/science.278.5344.1731b UR - http://dx.doi.org/10.1126/science.278.5344.1731b ER - TY - JOUR AU - Gaucher, S. P. TI - Expanded coverage of the human heart mitochondrial proteome using multidimensional liquid chromatography coupled with tandem mass spectrometry JA - J. Proteome Res. PY - 2004/// VL - 3 SP - 495 EP - 505 PB - Nature Publishing Group M3 - 10.1021/pr034102a N1 - 10.1021/pr034102a UR - http://dx.doi.org/10.1021/pr034102a ER - TY - JOUR AU - Mootha, V. K. TI - Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria JA - Cell PY - 2003/// VL - 115 SP - 629 EP - 640 PB - Nature Publishing Group M3 - 10.1016/S0092-8674(03)00926-7 N1 - 10.1016/S0092-8674(03)00926-7 UR - http://dx.doi.org/10.1016/S0092-8674(03)00926-7 ER - TY - JOUR AU - Taylor, S. W. TI - Characterization of the human heart mitochondrial proteome JA - Nature Biotechnol. PY - 2003/// VL - 21 SP - 281 EP - 286 PB - Nature Publishing Group M3 - 10.1038/nbt793 N1 - 10.1038/nbt793 UR - http://dx.doi.org/10.1038/nbt793 ER - TY - JOUR AU - Bains, R. K. TI - Visceral obesity without insulin resistance in late-onset obesity rats JA - Endocrinology PY - 2004/// VL - 145 SP - 2666 EP - 2679 PB - Nature Publishing Group M3 - 10.1210/en.2003-1608 N1 - 10.1210/en.2003-1608 UR - http://dx.doi.org/10.1210/en.2003-1608 ER - TY - JOUR AU - Schadt, E. E. AU - Lum, P. Y. TI - Reverse engineering gene networks to identify key drivers of complex disease phenotypes JA - J. Lipid Res. PY - 2006/// VL - 47 SP - 2601 EP - 2013 PB - Nature Publishing Group M3 - 10.1194/jlr.R600026-JLR200 N1 - 10.1194/jlr.R600026-JLR200 UR - http://dx.doi.org/10.1194/jlr.R600026-JLR200 ER - TY - JOUR AU - Lum, P. Y. TI - Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes JA - J. Neurochem. PY - 2006/// VL - 97 SP - 50 EP - 62 PB - Nature Publishing Group M3 - 10.1111/j.1471-4159.2006.03661.x N1 - 10.1111/j.1471-4159.2006.03661.x UR - http://dx.doi.org/10.1111/j.1471-4159.2006.03661.x ER - TY - JOUR AU - Ravasz, E. AU - Somera, A. L. AU - Mongru, D. A. AU - Oltvai, Z. N. AU - Barabasi, A. L. TI - Hierarchical organization of modularity in metabolic networks JA - Science PY - 2002/// VL - 297 SP - 1551 EP - 1555 PB - Nature Publishing Group M3 - 10.1126/science.1073374 N1 - 10.1126/science.1073374 UR - http://dx.doi.org/10.1126/science.1073374 ER - TY - JOUR AU - Haley, C. S. AU - Knott, S. A. TI - A simple regression method for mapping quantitative trait loci in line crosses using flanking markers JA - Heredity PY - 1992/// VL - 69 SP - 315 EP - 324 PB - Nature Publishing Group ER - TY - JOUR AU - Jiang, C. AU - Zeng, Z. B. TI - Multiple trait analysis of genetic mapping for quantitative trait loci JA - Genetics PY - 1995/// VL - 140 SP - 1111 EP - 1127 PB - Nature Publishing Group ER -