Figures and Tables

From the following article:

Variations in DNA elucidate molecular networks that cause disease

Yanqing Chen, Jun Zhu, Pek Yee Lum, Xia Yang, Shirly Pinto, Douglas J. MacNeil, Chunsheng Zhang, John Lamb, Stephen Edwards, Solveig K. Sieberts, Amy Leonardson, Lawrence W. Castellini, Susanna Wang, Marie-France Champy, Bin Zhang, Valur Emilsson, Sudheer Doss, Anatole Ghazalpour, Steve Horvath, Thomas A. Drake, Aldons J. Lusis & Eric E. Schadt

Nature 452, 429-435(27 March 2008)

doi:10.1038/nature06757

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Figure 1

The distal half of chromosome 1 strongly influences metabolic and gene expression traits.

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Figure 2

Genetic loci perturb molecular phenotypes that in turn lead to variations in disease-associated traits.

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Figure 3

Genes in the MEM network validated as having a causal relationship with obesity traits.

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Table 1

Gene sets significantly over-represented in the MEMN

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Table 2

Comparison of metabolic traits between Ppm1l-/- and Ppm1l+/+ mice

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