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From the following article:

Transcriptional repression mediated by repositioning of genes to the nuclear lamina

K. L. Reddy, J. M. Zullo, E. Bertolino & H. Singh

Nature 452, 243-247(13 March 2008)

doi:10.1038/nature06727

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Quantitative analysis of tethered loci by 3D DNA-immunoFISH.

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Figure 2

Lamin B, EMD and LAP2, but not NPCs, accumulate at sites of tethered foci.

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Figure 3

Tethering leads to transcriptional repression and histone deacetylation of genes at site of attachment to the INM.

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Figure 4

Inactive immunoglobulin heavy chain loci that are positioned at the nuclear periphery contact the nuclear lamina.

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