Access
To read this story in full you will need to login or make a payment (see right).
Insight
Nature 451, 904-913 (21 February 2008) | doi:10.1038/nature06796; Published online 20 February 2008
Open Innovation Challenges
-
Methods to Analyze Consumer Emotions
The Seeker is looking for methods to analyze consumer emotions. This Challenge requires only a writ...
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
- More Challenges
- Powered by:
nature jobs
Postdoctoral Research Associate
- Rice University
- Houston, Texas, USA
Research Scientist – Ecology of Phytoplankton and Primary Producers (Experimental Lakes Area)
- Fisheries and Oceans Canada (DFO)
- Winnipeg, Manitoba, Canada
Review Article Translating molecular discoveries into new therapies for atherosclerosis
Daniel J. Rader1 & Alan Daugherty2
Abstract
Atherosclerosis is characterized by the thickening of the arterial wall and is the primary cause of coronary artery disease and cerebrovascular disease, two of the most common causes of illness and death worldwide. Clinical trials have confirmed that certain lipoproteins and the renin–angiotensin–aldosterone system are important in the pathogenesis of atherosclerotic cardiovascular disease, and that interventions targeted towards these are beneficial. Furthermore, efforts to understand how risk factors such as high blood pressure, dysregulated blood lipids and diabetes contribute to atherosclerotic disease, as well as to understand the molecular pathogenesis of atherosclerotic plaques, are leading to new targets for therapy.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
The clot thickens?oxidized lipids and thrombosisNature Medicine News and Views (01 Sep 2007)
