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Nature 451, xvi (21 February 2008) | doi:10.1038/7181xvib; Published online 20 February 2008
Abstractions
A Holliday junction is a fleeting four-way crossover that occurs between DNA strands of the two chromosomes that make up a pair, allowing the reciprocal exchange of genetic information during a process known as homologous recombination. This mechanism was first proposed in 1964, and so far, only proteins from prokaryotes — organisms whose cells lack a nuclear membrane — have been shown to promote the formation of this type of DNA structure.
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