Table of contents

Funds run dry for sea-fertilization project p879

doi:10.1038/451879b

Systems biologists hatch plan for virtual human p879

doi:10.1038/451879c

India has a key satellite antenna stolen for scrap p879

doi:10.1038/451879d

Medical schools still not declaring financial conflicts p879

doi:10.1038/451879e

Harvard adopts opt-out open-access policy p879

doi:10.1038/451879f

News Features

Energy: Not your father's biofuels p880

If biofuels are to help the fight against climate change, they have to be made from more appropriate materials and in better ways. Jeff Tollefson asks what innovation can do to improve the outlook.

doi:10.1038/451880a

Full Text | PDF (1,356K)

Solar power: A flight to remember p884

The dream of perpetual flight without fuel has inspired pilots to take to the skies in solar-powered planes. Vicki Cleave looks at a mission to fly a solar plane through the night — and around the world.

doi:10.1038/451884a

Full Text | PDF (777K)

Correspondence

Non-traditional publishing choices can enrich science p887

Zeba Wunderlich & Kishore Kuchibhotla

doi:10.1038/451887a

Pakistan needs a powerful ethics and integrity body p887

Muhammad Mukhtar & Zahida Parveen

doi:10.1038/451887b

Albedo-watching satellite needed to monitor change p887

Francisco P. J. Valero & Robert J. Charlson

doi:10.1038/451887c

Citations in supplementary information are invisible p887

Frank Seeber

doi:10.1038/451887d

Books and Arts

Architectural healing p889

A detailed history explores the symbiosis of modern scientific medicine and hospital design.

D. Kirk Hamilton reviews Medicine by Design: The Architect and the Modern Hospital, 1893–1943 by AnnMarie Adams

doi:10.1038/451889a

Full Text | PDF (512K)

Quest for extraterrestrial life p890

Bruce Jakosky reviews The Living Cosmos: Our Search for Life in the Universe by Chris Impey

doi:10.1038/451890a

Full Text | PDF (261K)

See also: Editor's summary

Exhibition: Cultures in the capital p891

Jane Rees reviews sk-interfaces

doi:10.1038/451891a

Full Text | PDF (173K)

Text book for space shakers p891

Neil Turok reviews Gravitational Waves: Volume 1: Theory and Experiments by Michele Maggiore

doi:10.1038/451891b

Full Text | PDF (424K)

Exhibition: Time revisited p892

Joanne Baker reviews Art in You

doi:10.1038/451892a

Full Text | PDF (309K)

News and Views

Complex systems: Ecology for bankers p893

There is common ground in analysing financial systems and ecosystems, especially in the need to identify conditions that dispose a system to be knocked from seeming stability into another, less happy state.

Robert M. May, Simon A. Levin & George Sugihara

doi:10.1038/451893a

Full Text | PDF (480K)

50 & 100 Years Ago p894

doi:10.1038/451894a

Full Text | PDF (95K)

Materials science: The gift of healing p895

Synthesis of a rubber-like material that can be recycled might not seem exciting. But one that can also repeatedly repair itself at room temperature, without adhesives, really stretches the imagination.

Justin L. Mynar & Takuzo Aida

doi:10.1038/451895a

Full Text | PDF (381K)

See also: Editor's summary

Evolutionary biology: Bridge over troublesome plastids p896

Identification of a direct link between apicomplexan parasites and their algal ancestors is a development full of promise. It illuminates a dark corner in the evolution of photosynthesis, and further insights are to come.

Patrick J. Keeling

doi:10.1038/451896a

Full Text | PDF (259K)

See also: Editor's summary

Organic chemistry: Solid awakening p897

Once dismissed as chemical graveyards, organic solids can in fact be manipulated to surprising effect: one example is a crystal designed to embark on a remarkable domino-rally of reactions when bathed in light.

Leonard R. MacGillivray

doi:10.1038/451897a

Full Text | PDF (284K)

Epidemiology: Emerging diseases go global p898

Novel human infections continue to appear all over the world, but the risk is higher in some regions than others. Identification of emerging-disease 'hotspots' will help target surveillance work.

Mark E. J. Woolhouse

doi:10.1038/451898a

Full Text | PDF (174K)

See also: Editor's summary

Geophysics: Slab sliding away p899

Does material that is subducted into Earth's interior at plate boundaries penetrate very far down? A model that links subsurface dynamics with the motion of the plates above provides a fresh approach to the question.

Scott King

doi:10.1038/451899a

Full Text | PDF (151K)

Cell biology: DNA versus membrane p900

Before it divides, a bacterium must move its replicated chromosomes away from the site of division, or risk having its DNA trapped in the membranes that separate the divided cells. How does it avoid this catastrophe?

Ling Juan Wu & Jeff Errington

doi:10.1038/451900a

Full Text | PDF (2,328K)

Insight: Cardiovascular disease

Insight: Cardiovascular disease -

Produced with support from:

Cardiovascular disease p903

Michael Basson

doi:10.1038/451903a

Full Text | PDF (100K)

Translating molecular discoveries into new therapies for atherosclerosis p904

Daniel J. Rader & Alan Daugherty

doi:10.1038/nature06796

Abstract | Full Text | PDF (1,912K)

Triggers, targets and treatments for thrombosis p914

Nigel Mackman

doi:10.1038/nature06797

Abstract | Full Text | PDF (1,104K)

Tackling heart failure in the twenty-first century p919

James O. Mudd & David A. Kass

doi:10.1038/nature06798

Abstract | Full Text | PDF (1,173K)

A genetic framework for improving arrhythmia therapy p929

Björn C. Knollmann & Dan M. Roden

doi:10.1038/nature06799

Abstract | Full Text | PDF (673K)

Stem-cell therapy for cardiac disease p937

Vincent F. M. Segers & Richard T. Lee

doi:10.1038/nature06800

Abstract | Full Text | PDF (2,410K)

The developmental genetics of congenital heart disease p943

Benoit G. Bruneau

doi:10.1038/nature06801

Abstract | Full Text | PDF (329K)

The search for new cardiovascular biomarkers p949

Robert E. Gerszten & Thomas J. Wang

doi:10.1038/nature06802

Abstract | Full Text | PDF (217K)

Imaging of atherosclerotic cardiovascular disease p953

Javier Sanz & Zahi A. Fayad

doi:10.1038/nature06803

Abstract | Full Text | PDF (2,567K)

Brief Communications Arising

Is recent major hurricane activity normal? pE5

Urs Neu

doi:10.1038/nature06576

First paragraph | Full Text | PDF (129K)

Nyberg et al. reply pE6

Johan Nyberg, Björn A. Malmgren, Amos Winter, Mark R. Jury, K. Halimeda Kilbourne & Terrence M. Quinn

doi:10.1038/nature06577

First paragraph | Full Text | PDF (129K)

Corrigendum

Genotyping of Rhesus SCNT pluripotent stem cell lines pE7

David S. Cram, Bi Song & Alan O. Trounson

doi:10.1038/nature06759

Full Text | PDF (57K)

Articles

A photosynthetic alveolate closely related to apicomplexan parasites p959

Robert B. Moore, Miroslav Oborník, Jan Janou s caron kovec, Tomá s caron Chrudimský, Marie Vancová, David H. Green, Simon W. Wright, Noel W. Davies, Christopher J. S. Bolch, Kirsten Heimann, Jan S caron lapeta, Ove Hoegh-Guldberg, John M. Logsdon & Dee A. Carter

doi:10.1038/nature06635

Abstract | Full Text | PDF (734K) | Supplementary information

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance p964

Xiaoyong Yang, Pat P. Ongusaha, Philip D. Miles, Joyce C. Havstad, Fengxue Zhang, W. Venus So, Jeffrey E. Kudlow, Robert H. Michell, Jerrold M. Olefsky, Seth J. Field & Ronald M. Evans

doi:10.1038/nature06668

Abstract | Full Text | PDF (692K) | Supplementary information

See also: Editor's summary

Letters

Energetic neutral atoms as the explanation for the high-velocity hydrogen around HD 209458b p970

M. Holmström, A. Ekenbäck, F. Selsis, T. Penz, H. Lammer & P. Wurz

doi:10.1038/nature06600

First paragraph | Full Text | PDF (466K) | Supplementary information

See also: Editor's summary

Martian stepped-delta formation by rapid water release p973

Erin R. Kraal, Maurits van Dijk, George Postma & Maarten G. Kleinhans

doi:10.1038/nature06615

First paragraph | Full Text | PDF (457K) | Supplementary information

See also: Editor's summary

Self-healing and thermoreversible rubber from supramolecular assembly p977

Philippe Cordier, François Tournilhac, Corinne Soulié-Ziakovic & Ludwik Leibler

doi:10.1038/nature06669

First paragraph | Full Text | PDF (555K) | Supplementary information

Evidence of lower-mantle slab penetration phases in plate motions p981

Saskia Goes, Fabio A. Capitanio & Gabriele Morra

doi:10.1038/nature06691

First paragraph | Full Text | PDF (507K) | Supplementary information

A fundamental avian wing-stroke provides a new perspective on the evolution of flight p985

Kenneth P. Dial, Brandon E. Jackson & Paolo Segre

doi:10.1038/nature06517

First paragraph | Full Text | PDF (1,294K) | Supplementary information

See also: Editor's summary

Global trends in emerging infectious diseases p990

Kate E. Jones, Nikkita G. Patel, Marc A. Levy, Adam Storeygard, Deborah Balk, John L. Gittleman & Peter Daszak

doi:10.1038/nature06536

First paragraph | Full Text | PDF (1,288K) | Supplementary information

Proportionally more deleterious genetic variation in European than in African populations p994

Kirk E. Lohmueller, Amit R. Indap, Steffen Schmidt, Adam R. Boyko, Ryan D. Hernandez, Melissa J. Hubisz, John J. Sninsky, Thomas J. White, Shamil R. Sunyaev, Rasmus Nielsen, Andrew G. Clark & Carlos D. Bustamante

doi:10.1038/nature06611

First paragraph | Full Text | PDF (302K) | Supplementary information

See also: Editor's summary

Genotype, haplotype and copy-number variation in worldwide human populations p998

Mattias Jakobsson, Sonja W. Scholz, Paul Scheet, J. Raphael Gibbs, Jenna M. VanLiere, Hon-Chung Fung, Zachary A. Szpiech, James H. Degnan, Kai Wang, Rita Guerreiro, Jose M. Bras, Jennifer C. Schymick, Dena G. Hernandez, Bryan J. Traynor, Javier Simon-Sanchez, Mar Matarin, Angela Britton, Joyce van de Leemput, Ian Rafferty, Maja Bucan, Howard M. Cann, John A. Hardy, Noah A. Rosenberg & Andrew B. Singleton

doi:10.1038/nature06742

First paragraph | Full Text | PDF (1,555K) | Supplementary information

See also: Editor's summary

A role for adult TLX-positive neural stem cells in learning and behaviour p1004

Chun-Li Zhang, Yuhua Zou, Weimin He, Fred H. Gage & Ronald M. Evans

doi:10.1038/nature06562

First paragraph | Full Text | PDF (645K) | Supplementary information

See also: Editor's summary

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1 p1008

Zoltan Arany, Shi-Yin Foo, Yanhong Ma, Jorge L. Ruas, Archana Bommi-Reddy, Geoffrey Girnun, Marcus Cooper, Dina Laznik, Jessica Chinsomboon, Shamina M. Rangwala, Kwan Hyuck Baek, Anthony Rosenzweig & Bruce M. Spiegelman

doi:10.1038/nature06613

First paragraph | Full Text | PDF (543K) | Supplementary information

See also: Editor's summary

A PtdIns4,5P₂-regulated nuclear poly(A) polymerase controls expression of select mRNAs p1013

David L. Mellman, Michael L. Gonzales, Chunhua Song, Christy A. Barlow, Ping Wang, Christina Kendziorski & Richard A. Anderson

doi:10.1038/nature06666

First paragraph | Full Text | PDF (886K) | Supplementary information

Formation and branch migration of Holliday junctions mediated by eukaryotic recombinases p1018

Yasuto Murayama, Yumiko Kurokawa, Kouta Mayanagi & Hiroshi Iwasaki

doi:10.1038/nature06609

First paragraph | Full Text | PDF (509K) | Supplementary information

Corrigendum

The nonlinear Fano effect p1022

M. Kroner, A. O. Govorov, S. Remi, B. Biedermann, S. Seidl, A. Badolato, P. M. Petroff, W. Zhang, R. Barbour, B. D. Gerardot, R. J. Warburton & K. Karrai

doi:10.1038/nature06728

Erratum

Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA p1022

Di Yu, Andy Hee-Meng Tan, Xin Hu, Vicki Athanasopoulos, Nicholas Simpson, Diego G. Silva, Andreas Hutloff, Keith M. Giles, Peter J. Leedman, Kong Peng Lam, Christopher C. Goodnow & Carola G. Vinuesa

doi:10.1038/nature06729

Corrigenda

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4 p1022

Mark Gilchrist, Vesteinn Thorsson, Bin Li, Alistair G. Rust, Martin Korb, Jared C. Roach, Kathleen Kennedy, Tsonwin Hai, Hamid Bolouri & Alan Aderem

doi:10.1038/nature06779

Depth of a strong jovian jet from a planetary-scale disturbance driven by storms p1022

A. Sánchez-Lavega, G. S. Orton, R. Hueso, E. García-Melendo, S. Pérez-Hoyos, A. Simon-Miller, J. F. Rojas, J. M. Gómez, P. Yanamandra-Fisher, L. Fletcher, J. Joels, J. Kemerer, J. Hora, E. Karkoschka, I. de Pater, M. H. Wong, P. S. Marcus, N. Pinilla-Alonso, F. Carvalho, C. Go, D. Parker, M. Salway, M. Valimberti, A. Wesley & Z. Pujic

doi:10.1038/nature06807

Naturejobs

Prospect

Prospects p1023

Introducing the careers network from Naturejobs.

Gene Russo

doi:10.1038/nj7181-1023a

Full Text | PDF (70K)

Special Report

The new networking nexus p1024

A crop of websites is making networking among scientists easier than ever. Virginia Gewin logs in.

Virginia Gewin

doi:10.1038/nj7181-1024a

Full Text | PDF (411K)

Career View

Josephine Briggs, director, US National Center for Complementary and Alternative Medicine, Bethesda, Maryland p1026

Incoming director seeks to get centre for alternative medicine back on track.

Virginia Gewin

doi:10.1038/nj7181-1026a

Full Text | PDF (82K)

Take a turn as a rotator p1026

Taking a turn at grant-review duties can have its benefits.

Ted Agres

doi:10.1038/nj7181-1026b

Full Text | PDF (82K)

Our strange fellowship p1026

Humans can be exhausting. Sometimes I prefer the company of baboons.

Aliza le Roux

doi:10.1038/nj7181-1026c

Full Text | PDF (82K)

Highlights

Opportunities: The National Institutes of Health

doi:10.1038/nj0196

Full Text | PDF (808K)