Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Article
Nature 451, 725-729 (7 February 2008) | doi:10.1038/nature06537;
Open Innovation Challenges
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
- More Challenges
- Powered by:
nature jobs
Head of Analytical R&D
- Syngene International Limited
- Bangalore 560 099 India
Postdoctoral Fellow in Immunology
- The Scripps Research Institute
- N Torrey Pines Rd, San Diego, CA, USA
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
Successful vaccines contain not only protective antigen(s) but also an adjuvant component that triggers innate immune activation and is necessary for their optimal immunogenicity. In the case of DNA vaccines, this consists of plasmid DNA; however, the adjuvant element(s) as well as its intra- and inter-cellular innate immune signalling pathway(s) leading to the encoded antigen-specific T- and B-cell responses remain unclear.
&
Abstract
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
