Table of contents

indicates content that is available online only

Making the paper: Ronald Cohen pxi

Computational theory reveals an unusual quality in a pure compound.

doi:10.1038/7178xia


Abstractions pxi

doi:10.1038/7178xib


From the blogosphere pxi

doi:10.1038/7178xic


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Editorials

Towards falling emissions p499

Although Europe's new energy plans may be too prescriptive on the means of achieving the goals, they offer the world an encouraging way forward.

doi:10.1038/451499a


Secret treasure-troves restored p500

Reflecting on the endeavours of scientists past can provide both inspiration and pleasure.

doi:10.1038/451500a


A quantum of solace p500

As the US writers' strike rolls on, now is the time for scientists to extend the hand of friendship.

doi:10.1038/451500b


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Research Highlights

Research highlights p502

doi:10.1038/451502a


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Journal Club

Journal club p503

Nicholas Katsanis

doi:10.1038/451503a


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News

Europe spells out action plan for emissions targets p504

Heavy industry set to pay for allowances under carbon-trading scheme.

Quirin Schiermeier

doi:10.1038/451504a


Canada abolishes its national science adviser p505

After just four years, government axes post.

Hannah Hoag

doi:10.1038/451505a


Sidelines p506

Scribbles on the margins of science.

doi:10.1038/451506a


Cash for Russian nuclear scientists criticized p506

US payments to beat proliferation attacked as ineffective.

Eric Hand

doi:10.1038/451506b


Snapshot: Search for Higgs primed to start p507

Assembly of detector completes Large Hadron Collider.

Geoff Brumfiel

doi:10.1038/451507a


Funding freeze shakes Russia's prodigals p507

Academy pulls the plug on research programme.

Quirin Schiermeier

doi:10.1038/451507b


New York to police air monitoring p508

Legislation threatens to hamper research projects.

Rachel Courtland

doi:10.1038/451508a


Reviewer leaked Avandia study to drug firm p509

GlaxoSmithKline told early of diabetes blockbuster's links to heart attacks.

Brian Vastag

doi:10.1038/451509a


Fossil reptiles mired in controversy p510

Name-calling sparks dispute over aetosaurs.

Rex Dalton

doi:10.1038/451510a


Kidney expert to head holistic-medicine centre p511

doi:10.1038/451511a


Early-warning system underestimates quake p511

doi:10.1038/451511b


Synthetic genome paves the way to artificial life p511

doi:10.1038/451511c


France and India to expand scientific collaborations p511

doi:10.1038/451511d


OncoMed scores drug deal for $1.4 billion with Glaxo p511

doi:10.1038/451511e


Gates foundation gives cash for agriculture in Africa p511

doi:10.1038/451511f


Correction p511

doi:10.1038/451511g


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News Features

Human behaviour: Killer instincts p512

What can evolution say about why humans kill — and about why we do so less than we used to? Dan Jones reports.

doi:10.1038/451512a


Genome studies: Genetics by numbers p516

Genomewide association studies are starting to turn up increasingly reliable disease markers. Monya Baker investigates where we are now and what comes next.

doi:10.1038/451516a


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Correspondence

The action of enhancers can lead to addiction p520

Nora D. Volkow & James M. Swanson

doi:10.1038/451520a


Drugs can be used to treat more than disease p520

Nick Bostrom

doi:10.1038/451520b


Low dose of alertness drug counters 'family fatigue' p520

Charles Eaton

doi:10.1038/451520c


Drugging unruly children is a method of social control p521

Steven Rose

doi:10.1038/451521a


Humans have always tried to improve their condition p521

John Harris & Muireann Quigley

doi:10.1038/451521b


Policy must recognize drug impact on different sectors p521

Robin Pierce & Judy Illes

doi:10.1038/451521c


Rationality is a better basis for ethics than repugnance p521

Martha J. Farah

doi:10.1038/451521d


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Books and Arts

Trinity says: Let's talk p522

Dublin's new Science Gallery hopes to dissolve barriers between science and city through conversation. Director Michael John Gorman explains how the gentle art will bring new voices to research.

Michael John Gorman

doi:10.1038/451522a


Van Allen remembered as belts turn 50 p523

doi:10.1038/451523a


Starvation: crime and punishment p524

doi:10.1038/451524a


Exhibition: Ancient orders of nature p525

doi:10.1038/451525a


Hidden treasures: The University History Museum in Pavia p526

In the first of a monthly series on small museums, Alison Abbott profiles the University History Museum in Pavia, which recalls the key role of northern Italy in Enlightenment science.

Alison Abbott

doi:10.1038/451526a


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News and Views

性決定: お熱いのがお好き(そうじゃないのもいるけど)

Sex determination: Some like it hot (and some don't) p527

There is a widely accepted theoretical explanation for why sex in some species is determined at the embryo stage by environmental factors such as temperature. That theory is now supported by experiment.

David Crews & James J. Bull

doi:10.1038/451527a


ナノ材料: DNA塩基対合を使う結晶化

Nanomaterials: Golden handshake p528

Three-dimensional nanoparticle arrays are likely to be the foundation of future optical and electronic materials. A promising way to assemble them is through the transient pairings of complementary DNA strands.

John C. Crocker

doi:10.1038/451528a


50 & 100 Years Ago p529

doi:10.1038/451529a


細胞生物学: 死ぬほど抱きしめたい

Cell biology: Dying to hold you p530

Certain cells bind so tightly to each other that, on occasion, one cell ends up inside another, usually with fatal consequences for the ingested cell. This involuntary cell death might help protect us from cancer.

Kimon Doukoumetzidis & Michael O. Hengartner

doi:10.1038/451530a


宇宙論: 太古の加速の様子

Cosmology: An ancient view of acceleration p531

The Universe is expanding ever faster — the effect of 'dark energy', most astronomers believe. Surveys of how galaxies were distributed in the past could provide precise clues to what is driving this acceleration.

Michael A. Strauss

doi:10.1038/451531a


イオンチャネル: インフルエンザウイルスのプロトンチャネルの構造

Ion channels: Coughing up flu's proton channels p532

Two research teams have captured snapshots of the influenza virus's membrane-bound hydrogen-ion channel, which is essential for infection and virulence. Their findings agree on the basics, but differ in details.

Christopher Miller

doi:10.1038/451532a


デバイス物理学: ナノワイヤーを使った有望なディスプレイ

Device physics: Nanowires' display of potential p533

The future of the video display is both flexible and transparent. Finding a material for the attendant electronics that is small-scale, bendy and see-through is a tall order — but a promising candidate is emerging.

Hagen Klauk

doi:10.1038/451533a


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Article

ショウジョウバエ体節形成における調節配列に基づく発現パターンの予測

Predicting expression patterns from regulatory sequence in Drosophila segmentation p535

Eran Segal, Tali Raveh-Sadka, Mark Schroeder, Ulrich Unnerstall & Ulrike Gaul

doi:10.1038/nature06496


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Letters

宇宙の加速の性質の銀河の赤方偏移の歪みを用いた検証

A test of the nature of cosmic acceleration using galaxy redshift distortions p541

L. Guzzo, M. Pierleoni, B. Meneux, E. Branchini, O. Le Fèvre, C. Marinoni, B. Garilli, J. Blaizot, G. De Lucia, A. Pollo, H. J. McCracken, D. Bottini, V. Le Brun, D. Maccagni, J. P. Picat, R. Scaramella, M. Scodeggio, L. Tresse, G. Vettolani, A. Zanichelli, C. Adami, S. Arnouts, S. Bardelli, M. Bolzonella, A. Bongiorno, A. Cappi, S. Charlot, P. Ciliegi, T. Contini, O. Cucciati, S. de la Torre, K. Dolag, S. Foucaud, P. Franzetti, I. Gavignaud, O. Ilbert, A. Iovino, F. Lamareille, B. Marano, A. Mazure, P. Memeo, R. Merighi, L. Moscardini, S. Paltani, R. Pellò, E. Perez-Montero, L. Pozzetti, M. Radovich, D. Vergani, G. Zamorani & E. Zucca

doi:10.1038/nature06555


強誘電体におけるモルフォトロピック相境界の起源

Origin of morphotropic phase boundaries in ferroelectrics p545

Muhtar Ahart, Maddury Somayazulu, R. E. Cohen, P. Ganesh, Przemyslaw Dera, Ho-kwang Mao, Russell J. Hemley, Yang Ren, Peter Liermann & Zhigang Wu

doi:10.1038/nature06459


コロイドナノ粒子のDNA誘導結晶化

DNA-guided crystallization of colloidal nanoparticles p549

Dmytro Nykypanchuk, Mathew M. Maye, Daniel van der Lelie & Oleg Gang

doi:10.1038/nature06560


DNAでプログラム可能なナノ粒子結晶化

DNA-programmable nanoparticle crystallization p553

Sung Yong Park, Abigail K. R. Lytton-Jean, Byeongdu Lee, Steven Weigand, George C. Schatz & Chad A. Mirkin

doi:10.1038/nature06508


近年の大西洋のハリケーン活動の増大に対する海面温暖化の大きな寄与

Large contribution of sea surface warming to recent increase in Atlantic hurricane activity p557

Mark A. Saunders & Adam S. Lea

doi:10.1038/nature06422


千島列島中央部の巨大双子地震と地震応力移動サイクル

A great earthquake doublet and seismic stress transfer cycle in the central Kuril islands p561

Charles J. Ammon, Hiroo Kanamori & Thorne Lay

doi:10.1038/nature06521


爬虫類の一種にみられる温度に依存した性決定の適応的意義

The adaptive significance of temperature-dependent sex determination in a reptile p566

D. A. Warner & R. Shine

doi:10.1038/nature06519


線虫のlethargusは睡眠に似た状態である

Lethargus is a Caenorhabditis elegans sleep-like state p569

David M. Raizen, John E. Zimmerman, Matthew H. Maycock, Uyen D. Ta, Young-jai You, Meera V. Sundaram & Allan I. Pack

doi:10.1038/nature06535


NLRX1は、ミトコンドリアの抗ウイルス免疫の調節因子である

NLRX1 is a regulator of mitochondrial antiviral immunity p573

Chris B. Moore, Daniel T. Bergstralh, Joseph A. Duncan, Yu Lei, Thomas E. Morrison, Albert G. Zimmermann, Mary A. Accavitti-Loper, Victoria J. Madden, Lijun Sun, Zhengmao Ye, John D. Lich, Mark T. Heise, Zhijian Chen & Jenny P-Y. Ting

doi:10.1038/nature06501


マクロファージ遊走阻止因子は、虚血心臓のAMP活性化プロテインキナーゼを刺激する

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart p578

Edward J. Miller, Ji Li, Lin Leng, Courtney McDonald, Toshiya Atsumi, Richard Bucala & Lawrence H. Young

doi:10.1038/nature06504


DBC1はSIRT1の負の調節因子である

DBC1 is a negative regulator of SIRT1 p583

Ja-Eun Kim, Junjie Chen & Zhenkun Lou

doi:10.1038/nature06500


DBC1によるデアセチラーゼSIRT1の負の調節

Negative regulation of the deacetylase SIRT1 by DBC1 p587

Wenhui Zhao, Jan-Philipp Kruse, Yi Tang, Sung Yun Jung, Jun Qin & Wei Gu

doi:10.1038/nature06515


インフルエンザAウイルスM2プロトンチャネルの構造と作用機構

Structure and mechanism of the M2 proton channel of influenza A virus p591

Jason R. Schnell & James J. Chou

doi:10.1038/nature06531


インフルエンザウイルス・プロトンチャネルの機能と阻害の構造基盤

Structural basis for the function and inhibition of an influenza virus proton channel p596

Amanda L. Stouffer, Rudresh Acharya, David Salom, Anna S. Levine, Luigi Di Costanzo, Cinque S. Soto, Valentina Tereshko, Vikas Nanda, Steven Stayrook & William F. DeGrado

doi:10.1038/nature06528


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Retraction

Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript p600

A. Gupta, J. J. Gartner, P. Sethupathy, A. G. Hatzigeorgiou & N. W. Fraser

doi:10.1038/nature06621


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Naturejobs

Prospect

Prospects p601

The complexities of conducting science in India.

Gene Russo

doi:10.1038/nj7178-601a


Career View

Rolf-Dieter Heuer, director-general, CERN, Geneva, Switzerland p602

New director-general coming to CERN.

Virginia Gewin

doi:10.1038/nj7178-602a


Singapore gears up for translation p602

Singapore's Institute of Medical Biology strives for translation.

Ewen Callaway

doi:10.1038/nj7178-602b


Biopolis dreams p602

The Biopolis offers me vast opportunity and a challenging new laboratory culture.

Amanda Goh

doi:10.1038/nj7178-602c


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Futures

Annie Webber p604

The customer is always right.

Elizabeth Bear

doi:10.1038/451604a



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