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Nature 451, 527-528 (31 January 2008) | doi:10.1038/451527a; Published online 30 January 2008

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Sex determination: Some like it hot (and some don't)

David Crews1 & James J. Bull1

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There is a widely accepted theoretical explanation for why sex in some species is determined at the embryo stage by environmental factors such as temperature. That theory is now supported by experiment.

How the sex of offspring is determined seems simple enough if you don't look beyond ourselves. For humans, the system is genotypic: two X chromosomes, and you're female; an X and a Y, and you're male.

  1. David Crews and James J. Bull are in the Section of Integrative Biology, University of Texas at Austin, Austin, Texas 78712, USA.
    Email: crews@mail.utexas.edu
    Email: bull@mail.utexas.edu

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