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From the following article:

Structural basis for the function and inhibition of an influenza virus proton channel

Amanda L. Stouffer, Rudresh Acharya, David Salom, Anna S. Levine, Luigi Di Costanzo, Cinque S. Soto, Valentina Tereshko, Vikas Nanda, Steven Stayrook & William F. DeGrado

Nature 451, 596-599(31 January 2008)

doi:10.1038/nature06528

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Crystal structure of the M2 proton channel from the influenza A virus.

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Figure 2

Asymmetric structure of the C-terminal His/Trp gate of M2TM.

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Figure 3

Superpositions of the crystallographic tetramer demonstrate conformational differences in the C-terminal gating region of the channel.

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Figure 4

Minimal mechanism of activation and conductance through the channel.

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