Unravelling a mechanism that stops HIV travelling between cells.
doi:10.1038/7177xia
Table of contents
Volume 451 Number 7177 pp373-498
(this content only available online) indicates content that is available online only
Making the paper: Paul Bieniasz pxi
Abstractions pxi
doi:10.1038/7177xib
From the blogosphere pxi
doi:10.1038/7177xic
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Editorials
Fuel's paradise p373
The utopian urge to separate the world's nuclear-fuel cycles from national strategic ambitions has merit.
doi:10.1038/451373a
Competition and noise p373
Mitt Romney's pledge to plough $20 billion a year into energy research may signal an unseemly bidding war.
doi:10.1038/451373b
A little less Disneyland p374
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News
How the world invests in R&D p378
The changing face of public and private funding.
Rachel Courtland
doi:10.1038/451378a
International genome project launched p378
Three-year study will capture variation in 1,000 people.
Erika Check Hayden
doi:10.1038/451378b
Q&A: Larry Brilliant p379
He's a physician who has had a major role in the eradication of smallpox and in tackling blindness. Now Larry Brilliant is heading up Google.org, the dotcom giant's philanthropic arm, which plans to tackle emerging diseases, climate change and poverty. Declan Butler talks to him about his diseases strategy.
Declan Butler
doi:10.1038/451379a
Nuclear fuel: keeping it civil p380
In the third of a series of articles examining nuclear issues, Jeff Tollefson looks at options for fuelling a global boom in nuclear power stations without enabling nuclear proliferation.
Jeff Tollefson
doi:10.1038/451380a
A very mysterious foundation p382
Shroud of secrecy surrounds innovation organization.
Declan Butler
doi:10.1038/451382a
Creationists launch 'science' journal p382
Research within a biblical framework to be peer reviewed.
Geoff Brumfiel
doi:10.1038/451382b
Huge crystal baffles chemists p383
Molecular cluster defies accurate analysis.
Katharine Sanderson
doi:10.1038/451383a
Cellular memory hints at the origins of intelligence p385
Slime mould displays remarkable rhythmic recall.
Philip Ball
doi:10.1038/451385a
Sidelines p385
Scribbles on the margins of science.
doi:10.1038/451385b
NIH in the dark over conflicts of interest p386
doi:10.1038/451386a
Ice runway knocks weeks off journey to Antarctica p386
doi:10.1038/451386b
Early-stage human embryos cloned from adult cells p386
doi:10.1038/451386c
UK government under pressure over physics cuts p386
doi:10.1038/451386d
European registry makes stem-cell use transparent p386
doi:10.1038/451386e
Government abandons bid to save US jaguars p386
doi:10.1038/451386f
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Column
Shattered illusions p387
Last-minute cuts to the research budget have left US scientists nervous about future funding. David Goldston looks at what Congress and the president might do next.
David Goldston
doi:10.1038/451387a
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News Features
Virology: The battle within p388
Viral and microbial interactions within living tissues are more complex than previously thought. Melinda Wenner explores whether a periodic table of the infectious could help sort out the mess.
doi:10.1038/451388a
日本語要約 | Full Text | PDF (887K)
Defence research: Still in the lead? p390
Half a century after its creation, the Pentagon's Defense Advanced Research Projects Agency is considered a paragon of government innovation. But some question whether it is still relevant. Sharon Weinberger reports.
doi:10.1038/451390a
日本語要約 | Full Text | PDF (907K)
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Correspondence
Venezuelan students are campaigning for freedom p395
Independent institutes are being financially strangled p395
Government control has weakened universities p395
Social sciences worst off as projects remain unfunded p395
Grants awarded on the basis of political criteria p395
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Commentary
A tale of two citations p397
Are scientists publishing more duplicate papers? An automated search of seven million biomedical abstracts suggests that they are, report Mounir Errami and Harold Garner.
Mounir Errami & Harold Garner
doi:10.1038/451397a
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Books and Arts
Book: Behind the scenes p400
A Natural History Museum researcher unlocks its cluttered store rooms to expose an extraordinary past.
doi:10.1038/451400a
Book: Networking knowledge p401
doi:10.1038/451401a
Book: Parallel lives p401
doi:10.1038/451401b
Film: Science at Sundance p402
doi:10.1038/451402a
Preview: Revealing reptiles p402
doi:10.1038/451402b
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Essay
How the change agent has changed p403
As the US military's research arm turns fifty — and other branches of government seek to adopt its famously nimble approach — a former director reflects on what worked and what didn't.
Charles Herzfeld
doi:10.1038/451403a
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News and Views
炭素サイクル: 20世紀の収穫
Carbon cycle: Harvest of the century p405
A century-long record of levels of inorganic carbon in the Mississippi, extracted from the water-treatment plants of New Orleans, documents the changes wrought by shifting agricultural practices in the river's basin.
Emilio Mayorga
doi:10.1038/451405a
HIV/AIDS: ウイルスをつなぎとめる鎖
HIV/AIDS: Virus kept on a leash p406
Without its Vpu protein, the AIDS-associated virus HIV-1 becomes stuck to the surface of the human cell in which it has replicated. The mysterious factor that tethers HIV-1 is probably a cell-membrane protein.
Heinrich G. Göttlinger
doi:10.1038/nature06364
日本語要約 | Full Text | PDF (565K)
50 & 100 Years Ago p407
doi:10.1038/451407a
材料科学: こびとの国のライトスティック
Materials science: Lilliputian light sticks p408
Building two different fluorescing dyes into a composite organic nanocrystal makes a tunable light generator. At just the right dye proportions, a low-cost, highly efficient source of white light is the result.
Melissa Fardy & Peidong Yang
doi:10.1038/451408a
日本語要約 | Full Text | PDF (233K)
惑星科学: 木星の脈動する表面の下では
Planetary science: Under Jupiter's pulsing skin p409
Fast jet streams blow along the hallmark coloured bands that engirdle Jupiter's surface. By observing how storms erupt in these jet streams and disturb them, we can penetrate deeper into what lies beneath.
Kunio M. Sayanagi
doi:10.1038/451409a
日本語要約 | Full Text | PDF (363K)
材料科学: 簡単にできるデザイナーポア
Materials science: Designer pores made easy p410
Imagine being able to tweak the properties of a compound simply by replacing a molecular 'cartridge' with a different one. Just such a capability has been developed in a new class of porous crystalline materials.
Michael J. Zaworotko
doi:10.1038/451410a
日本語要約 | Full Text | PDF (449K)
ゲノミクス: 相手と同じ手段で対決する
Genomics: Fighting fire with fire p412
Mobile genetic elements called transposons could cause havoc in the genome if left unregulated. Of the various cellular defence strategies used to preserve genome integrity, one involves exploiting transposons themselves.
Daniel F. Voytas
doi:10.1038/451412a
日本語要約 | Full Text | PDF (440K)
光学: 光の広がりを止める
Optics: Against the spread of the light p413
Light that propagates without spreading or diffracting sounds like a theorist's pipedream. But it is a very real proposition, and could be used to illuminate some profound aspects of wave–particle duality.
Kishan Dholakia
doi:10.1038/451413a
日本語要約 | Full Text | PDF (111K)
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News and Views Q&A
分子生物学: 低分子RNAの広がる世界
Molecular biology: The expanding world of small RNAs p414
Molecular cell biology has long been dominated by a protein-centric view. But the emergence of small, non-coding RNAs challenges this perception. These plentiful RNAs regulate gene expression at different levels, and have essential roles in health and disease.
Helge Gro
hans
&
Witold Filipowicz
doi:10.1038/451414a
日本語要約 | Full Text | PDF (746K)
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Review
金属カルベノイドおよび金属ナイトレノイド挿入による触媒的C-H官能基化
Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion p417
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Articles
tetherinはレトロウイルスの放出を抑制し、HIV-1 Vpuの作用に拮抗する
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu p425
Stuart J. D. Neil, Trinity Zang & Paul D. Bieniasz
doi:10.1038/nature06553
日本語要約 | Full Text | PDF (1,239K) | Supplementary information
トランスポゾン由来のタンパク質による、宿主ゲノムのレトロトランスポゾン監視
Host genome surveillance for retrotransposons by transposon-derived proteins p431
Hugh P. Cam, Ken-ichi Noma, Hirotaka Ebina, Henry L. Levin & Shiv I. S. Grewal
doi:10.1038/nature06499
日本語要約 | Full Text | PDF (1,006K) | Supplementary information
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Letters
嵐によって引き起こされる惑星規模の擾乱から推定される強力な木星ジェットの深さ
Depth of a strong jovian jet from a planetary-scale disturbance driven by storms p437
A. Sánchez-Lavega, G. S. Orton, R. Hueso, E. García-Melendo, S. Pérez-Hoyos, A. Simon-Miller, J. F. Rojas, J. M. Gómez, P. Yanamandra-Fisher, L. Fletcher, J. Joels, J. Kemerer, J. Hora, E. Karkoschka, I. de Pater, M. H. Wong, P. S. Marcus, N. Pinilla-Alonso, F. Carvalho, C. Go, D. Parker, M. Salway, M. Valimberti, A. Wesley & Z. Pujic
doi:10.1038/nature06533
量子ドットにおける単一正孔スピンの光ポンピング
Optical pumping of a single hole spin in a quantum dot p441
Brian D. Gerardot, Daniel Brunner, Paul A. Dalgarno, Patrik Öhberg, Stefan Seidl, Martin Kroner, Khaled Karrai, Nick G. Stoltz, Pierre M. Petroff & Richard J. Warburton
doi:10.1038/nature06472
高密度Li-Be規則合金における電子状態の次元性の創発的低下
Emergent reduction of electronic state dimensionality in dense ordered Li-Be alloys p445
Ji Feng, Richard G. Hennig, N. W. Ashcroft & Roald Hoffmann
doi:10.1038/nature06442
ミシシッピ川からの人為的に増加した水フラックスと炭素フラックス
Anthropogenically enhanced fluxes of water and carbon from the Mississippi River p449
Peter A. Raymond, Neung-Hwan Oh, R. Eugene Turner & Whitney Broussard
doi:10.1038/nature06505
海洋地殻の変形と破壊がハワイ火山群の成長を支配している可能性
Deformation and rupture of the oceanic crust may control growth of Hawaiian volcanoes p453
Jean-Luc Got, Vadim Monteiller, Julien Monteux, Riad Hassani & Paul Okubo
doi:10.1038/nature06481
日本語要約 | Full Text | PDF (1,081K) | Supplementary information
熱帯の農業生態系にみられるアリ・コロニーのクラスターとロバストな臨界状態
Clusters of ant colonies and robust criticality in a tropical agroecosystem p457
John Vandermeer, Ivette Perfecto & Stacy M. Philpott
doi:10.1038/nature06477
GABAA受容体によるヒストンH2AX依存的な幹細胞の増殖制御
Histone H2AX-dependent GABAA receptor regulation of stem cell proliferation p460
Michael Andäng, Jens Hjerling-Leffler, Annalena Moliner, T. Kalle Lundgren, Gonçalo Castelo-Branco, Evanthia Nanou, Ester Pozas, Vitezslav Bryja, Sophie Halliez, Hiroshi Nishimaru, Johannes Wilbertz, Ernest Arenas, Martin Koltzenburg, Patrick Charnay, Abdeljabbar El Manira, Carlos F. Ibañez & Patrik Ernfors
doi:10.1038/nature06488
DscamとSidekickタンパク質群は脊椎動物の網膜において層特異的シナプス結合を制御する
Dscam and Sidekick proteins direct lamina-specific synaptic connections in vertebrate retina p465
Masahito Yamagata & Joshua R. Sanes
doi:10.1038/nature06469
日本語要約 | Full Text | PDF (2,144K) | Supplementary information
マウス網膜の神経突起の分枝形成とモザイク状の空間配置にはDSCAMが必要である
Neurite arborization and mosaic spacing in the mouse retina require DSCAM p470
Peter G. Fuerst, Amane Koizumi, Richard H. Masland & Robert W. Burgess
doi:10.1038/nature06514
日本語要約 | Full Text | PDF (1,908K) | Supplementary information
シロイヌナズナ成長の光およびジベレリンによる協調的調節
Coordinated regulation of Arabidopsisthaliana development by light and gibberellins p475
Suhua Feng, Cristina Martinez, Giuliana Gusmaroli, Yu Wang, Junli Zhou, Feng Wang, Liying Chen, Lu Yu, Juan M. Iglesias-Pedraz, Stefan Kircher, Eberhard Schäfer, Xiangdong Fu, Liu-Min Fan & Xing Wang Deng
doi:10.1038/nature06448
日本語要約 | Full Text | PDF (2,067K) | Supplementary information
光とジベレリンによる細胞の伸長制御の分子基盤
A molecular framework for light and gibberellin control of cell elongation p480
Miguel de Lucas, Jean-Michel Davière, Mariana Rodríguez-Falcón, Mariela Pontin, Juan Manuel Iglesias-Pedraz, Séverine Lorrain, Christian Fankhauser, Miguel Angel Blázquez, Elena Titarenko & Salomé Prat
doi:10.1038/nature06520
細菌鞭毛タンパク質の輸送におけるFliI ATPアーゼとプロトン駆動力の役割分担
Distinct roles of the FliI ATPase and proton motive force in bacterial flagellar protein export p485
Tohru Minamino & Keiichi Namba
doi:10.1038/nature06449
鞭毛のIII型分泌のエネルギー源
Energy source of flagellar type III secretion p489
Koushik Paul, Marc Erhardt, Takanori Hirano, David F. Blair & Kelly T. Hughes
doi:10.1038/nature06497
日本語要約 | Full Text | PDF (453K) | Supplementary information
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Region
Naturejobs
ProspectProspects p493
More countires are opening their doors to scientific immigration.
Paul Smaglik
doi:10.1038/nj7177-493a
Region
Argentina's pivotal moment p494
Rebuffing a troubled economic and political past, Argentina is trying to get on the science map with a new science ministry and attempts to retain young talent. Paul Smaglik reports.
Paul Smaglik
doi:10.1038/nj7177-494a
