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Nature 450, 1173-1175 (20 December 2007) | doi:10.1038/4501173a; Published online 19 December 2007
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Neuroscience: Neighbourly synapses
Bernardo L. Sabatini1
Abstract
Experiences shape our behaviour, memories and perception. Mechanistically, they also influence the brain's circuitry, and cooperativity between neuronal contacts during learning may contribute to this process.
Neuronal plasticity describes experience-related and development-associated structural and functional changes in the brain, which contribute to, among other processes, memory formation. Such changes occur at many levels; for example, depriving an animal of visual stimuli results in both small-scale modifications in neuronal receptors, and large-scale rewiring of neural circuits1, 2.
- Bernardo L. Sabatini is in the Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, Massachusetts 02115, USA.
Email: bsabatini@hms.harvard.edu
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