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Nature 450, 1091-1095 (28 November 2007) | doi:10.1038/nature06311;

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Distinct physiological states of Plasmodium falciparum in malaria-infected patients

Infection with the malaria parasite Plasmodium falciparum leads to widely different clinical conditions in children, ranging from mild flu-like symptoms to coma and death. Despite the immense medical implications, the genetic and molecular basis of this diversity remains largely unknown.

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