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Technology Feature

Nature 450, 1119 (13 December 2007) | doi:10.1038/4501119a; Published online 12 December 2007

Open Innovation Challenges

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Small RNAs: Thinking Small

"Each day you see major, significant publications on the roles of microRNAs in regulating pathways of genes involved in disease aetiology," says John Maraganore of Alnylam Pharmaceuticals in Cambridge, Massachusetts. Alongside the research into the mechanisms and roles of microRNA (miRNA) in disease, researchers are now starting to look at the potential of miRNA-based therapeutics.