TABLE 1
From the following article:
Small RNAs: Table of suppliers
Nature 450, 1121-1122(13 December 2007)
doi:10.1038/4501121a
| COMPANY | PRODUCTS/ACTIVITY | LOCATION | URL | |
|---|---|---|---|---|
| ||||
| RNAi therapeutic development | ||||
| Actigenics | Discovery and evaluation of miRNAs that alter gene expression for use in therapeutic development | Maurens-Scopont, France | http://www.actigenics.com | |
| Acuity Pharmaceuticals | RNAi-based treatments for age-related macular degeneration and diabetic retinopathy | Philadelphia, Pennsylvania | http://www.acuitypharma.com | |
| Alnylam Pharmaceuticals | siRNA–based therapeutics for RSV, liver cancer and hypercholesterolaemia | Cambridge, Massachusetts | http://www.alnylam.com | |
| ArmaGen Technologies | Developing technologies for siRNA delivery across the blood–brain barrier | Santa Monica, California | http://www.armagen.com | |
| Benitec | RNAi-based therapeutics for infectious disease, neurological disorders, cancer and autoimmune diseases | Melbourne, Australia | http://www.benitec.com | |
| Calando Pharmaceuticals | Technologies for the therapeutic use of RNAi | Pasadena, California | http://www.calandopharma.com | |
| Cequent Pharmaceuticals | Technologies for targeted delivery of RNAi using non-pathogenic bacteria to produce interfering RNA | Cambridge, Massachusetts | http://www.cequentpharma.com | |
| Intradigm | Systematic RNAi-based therapeutics focused on oncology | Rockville, Maryland | http://www.intradigm.com | |
| Isis Pharmaceuticals | RNA-inhibiting therapeutics; Vitravene, the first antisense drug to receive market clearance | Carlsbad, California | http://www.isispharm.com | |
| Merck | RNAi therapeutics using lipid-nanoparticle delivery | Rahway, New Jersey | http://www.merck.com | |
| NeoPharm | Cancer drugs and therapeutics using liposome-based delivery | Lake Forrest, Illinois | http://www.neophrm.com | |
| Regulus Therapeutics | miRNA-based therapeutics | Carlsbad, California | http://www.regulusrx.com | |
| Rosetta Genomics | miRNA therapeutics and diagnostics related to cancer | Rehovot, Israel | http://www.rosettagenomics.com | |
| RXi Pharmaceuticals | RNAi-based therapeutics to treat human diseases with an initial focus on neurodegenerative disease, oncology, diabetes and obesity | Worcester, Massachusetts | http://www.rxipharma.com | |
| Santaris Pharma | Assays for disease-related miRNAs as targets; designing and making miRNA antagonists | Copenhagen, Denmark | http://www.santaris.com | |
| Silence Therapeutics | Novel siRNA called AtuRNAi; therapeutic RNAi programme concentrated on cancer | Berlin, Germany | http://www.silence-therapeutics.com | |
| VirxSys | Therapeutics using lentiviral vectors for gene-therapy applications | Gaithersburg, Maryland | http://www.virxsys.com | |
| Tools and services for RNAi research | ||||
| Ambion | Silencer range of kits, vectors, siRNAs and reagents for RNAi; kits and products for RNA synthesis, isolation, quantitation and analysis | Austin, Texas | http://www.ambion.com | |
| Amaxa | Transfection reagents, siRNA test kits, culture media | Gaithersburg, Maryland | http://www.amaxa.com | |
| Applied Biosystems | Pre-designed and validated siRNAs; miRNA-expression reporter vector system; real-time PCR miRNA assays | Foster City, California | http://www.appliedbiosystems.com | |
| Asuragen | RNA-based therapeutic and diagnostics company with a core focus on miRNA | Austin, Texas | http://www.asuragen.com |  |
| BD Biosciences | Culture media, FACS range of flow cytometers; RNAi kits | San Jose, California | http://www.bdbiosciences.com | |
| Cenix BioScience | High-throughput applications of RNAi; siRNA design | Dresden, Germany | http://www.cenix-bioscience.com | |
| CombiMatrix | miRNA microarrays from various species | Mukilteo, Washington | http://www.combimatrix.com | |
| Dharmacon | Smartvector shRNA lentiviral particles for delivery; RNAi screening services; reagents for miRNA functional analysis | Lafayette, Colorado | http://www.dharmacon.com | |
| Eurogentec | Kits for amplification of human pre-miRNA; custom siRNA | Seraing, Belgium | http://www.eurogentec.com | |
| Exiqon | Gene-expression analysis services; identification of new miRNAs | Vedbaek, Denmark | http://www.exiqon.com | |
| GeneTools | Morpholino antisense oligonucleotides for blocking miRNA | Philomath, Oregon | http://www.gene-tools.com | |
| genOway | Services for gene knockdown in mice using RNAi technologies | Lyon, France | http://www.genoway.com | |
| Imgenex | Plasmid-based RNAi-expression vectors, prepared adenoviral vectors for shRNA delivery | San Diego, California | http://www.imgenex.com | |
| Integrated DNA Technologies | Small RNA cloning kit, antisense oligonucleotides | Coralville, Iowa | http://www.idtdna.com | |
| Invitrogen | Synthetic RNA, RNAi vectors, RNAi-knockdown services | Carlsbad, California | http://www.invitrogen.com | |
| Invivogen | psiRNA system for plasmid-based delivery of siRNA in mammalian cells | San Diego, California | http://www.invivogen.com | |
| Lentigen | Development of lentiviral vectors for RNA delivery | Baltimore, Maryland | http://www.lentigen.com | |
| Mirus Bio | RNAi-knockdown services in animals; products for nucleic-acid isolation, gene transfer and RNAi | Madison, Wisconsin | http://www.genetransfer.com | |
| MWG Biotech | Custom and pre-designed siRNA | Ebersberg, Germany | http://www.mwg-biotech.com | |
| New England Biolabs | Kits for the generation of RNA for RNAi experiments | Beverly, Massachusetts | http://www.neb.com | |
| OligoEngine | pSUPER RNAi vector system for gene silencing; custom oligonucleotides for all applications | Seattle, Washington | http://www.oligoengine.com | |
| Open Biosystems | RNAi libraries; lentiviral-packaging systems for shRNA delivery | Huntsville, Alabama | http://www.openbiosystems.com | |
| Polyplus-transfection | Transfection reagents for DNA, RNA and protein; developing siRNA delivery vehicles using cationic lipids and polymers | Illkirch, France | http://www.polyplus-transfection.com | |
| Promega | RNAi vectors and expression systems | Madison, Wisconsin | http://www.promega.com | |
| QIAGEN | Kits for the isolation, purification and labelling of miRNAs; pre-and custom-designed siRNAs; siRNA-transfection reagents | Germantown, Maryland | http://www1.qiagen.com | |
| Sigma Genosys | Custom siRNA synthesis; siRNA design service | The Woodlands, Texas | http://www.sigmaaldrich.com | |
| Stratagene | Tools and reagents for molecular-biology research; siRNA transfection system | La Jolla, California | http://www.stratagene.com | |
| Sylentis | SIRFINDER technology to determine siRNAs with potential pharmacological applications | Madrid, Spain | http://www.sylentis.com | |
| Targeting Systems | Targefect siRNA transfection system | Santee, California | http://www.targetingsystems.com | |
| Vectalys | Viral-vector production and cell transduction | Labege, France | http://www.vectalys.com | |
| General | ||||
| Agilent | Instrumentation for genomics and proteomics research | Santa Clara, California | http://www.agilent.com | |
| Beckman Coulter | Tools and systems for molecular biology, genomics and proteomics research | Fullerton, California | http://www.beckmancoulter.com | |
| Bio-Rad | Products, instruments and software for life-sciences research | Hercules, California | http://www.bio-rad.com | |
| BMG Labtechnologies | Microplate and array readers and handling systems | Offenburg, Germany | http://www.bmglabtech.com | |
| Brinkmann Instruments | Laboratory-instrument supplier; consumables | Westbury, New York | http://www.brinkmann.com | |
| Carl Zeiss | Imaging systems | Jena, Germany | http://www.zeiss.com | |
| EMD Biosciences | Calbiochem, Novabiochem, and Novagen product lines | San Diego, California | http://www.emdbiosciences.com | |
| Epicentre Biotechnologies | Enzymes for PCR and RT-PCR; DNA and RNA purification | Madison, Wisconsin | http://www.epibio.com | |
| Eppendorf | Consumables for molecular biology; instrumentation | Hamburg, Germany | http://www.eppendorf.com | |
| Gilson | Pipettes, automated liquid handling, liquid-chromatography systems and software | Middleton, Wisconsin | http://www.gilson.com | |
| Hamilton Company | Automated liquid-handling stations | Reno, Nevada | http://www.hamiltoncompany.com | |
| Millipore | Reagents and kits for cell biology, genomics and immunodetection | Billerica, Massachusetts | http://www.millipore.com | |
| MP Biomedicals | Reagents and chemicals for research | Aurora, Ohio | http://www.mpbio.com | |
| New Brunswick Scientific | Cell-cultivation systems, bioreactors, incubators, freezers | Edison, New Jersey | http://www.nbsc.com | |
| Nikon Instruments | Microscopy instrumentation, accessories and analysis software | Melville, New York | http://www.nikoninstruments.com | |
| PerkinElmer Life Sciences | Instruments, reagents and kits for life-sciences research | Waltham, Massachusetts | http://las.perkinelmer.com | |
| Pierce Chemical | Protein assays, purification, Western blotting | Rockford, Illinois | http://www.piercenet.com | |
| Roche Diagnostics | Reagents and kits for molecular biology; genomics instrumentations and software | Lewes, UK | http://www.roche-applied-science.com | |
| Sigma Aldrich | Reagents and kits for molecular-biology research; chemicals for life-sciences research | St Louis, Missouri | http://www.sigmaaldrich.com | |
| Takara Bio | Reagents, kits and consumables for molecular biology | Shiga, Japan | http://www.takara-bio.com | |
| Thermo Fisher Scientific | Life-sciences research consumables, automation and robotics, chemicals and consumables | Waltham, Massachusetts | http://www.thermofisher.com | |
| USB | Chemicals and reagents for molecular-biology research | Cleveland, Ohio | http://www.usbweb.com | |
| Wako Chemicals | Speciality chemicals supplier; clinical diagnostic reagents | Richmond, Virginia | http://www.wakousa.com | |
