Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 450, 799-800 (6 December 2007) | doi:10.1038/450799a; Published online 5 December 2007
Open Innovation Challenges
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
- More Challenges
- Powered by:
nature jobs
Associate Scientific Manager / Scientific Manager-Organic / Medicinal Chemistry
- Syngene International
- Bangalore, Karnataka 560099 India
Manager Client Services
- Indegene Lifesystems Pvt. Ltd
- Bengaluru 560 071 India
Diabetes: Missing links
Bart O. Roep1
Abstract
Researchers have now probably pinpointed all the genes in the MHC genomic region that are risk factors in type 1 diabetes. As the MHC is unusually rich in genes involved in immunity, this is truly exciting.
If there were 'Guinness World Records' for genomic regions, the major histocompatibility complex (MHC) would have several entries. It is the most gene-dense region in mammals, and variations in the human MHC are linked to susceptibility to more common diseases than any other region in the human genome.
- Bart O. Roep is in the Department of Immunohaematology and Blood Transfusion, Leiden University Medical Center, Albinusdreef 2, NL-2333 ZA Leiden, the Netherlands.
Email: boroep@lumc.nl
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with type 1 diabetes mellitus and celiac diseaseGenes and Immunity Original Article
