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Nature 450, 619 (29 November 2007) | doi:10.1038/450619a; Published online 28 November 2007
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Professor of Cognitive Neuroscience
- Karolinska Institute
- Stockholm Sweden
Assistant / Associate / Full Professor
- Northeastern University
- Boston, MA
Reproduction: The unusual suspect
Colin L. Stewart1
Abstract
The p53 protein is widely studied for its function as a tumour suppressor, preventing cancer. It emerges that this protein also has an essential physiological role in regulating embryo implantation in mice.
The p53 protein, which has been given the accolade 'guardian of the genome', is a celebrity among cellular proteins. If you search the PubMed database for p53, you'll get more than 44,000 hits, the vast majority of which discuss the role of this protein in protecting cells from the consequences of stress-induced DNA damage.
- Colin L. Stewart is at the Institute of Medical Biology, 8A Biomedical Grove, 06-06 Immunos, 138648 Singapore.
Email: colin.stewart@imb.a-star.edu.sg
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RESEARCH
Hyperglycemia Enhances DNA Fragmentation After Transient Cerebral IschemiaJournal of Cerebral Blood Flow & Metabolism Original Article
p53 regulates maternal reproduction through LIFNature Letters to Editor (29 Nov 2007)
