Supplementary information

From the following article:

The origin of spontaneous activity in the developing auditory system

Nicolas X. Tritsch, Eunyoung Yi, Jonathan E. Gale, Elisabeth Glowatzki & Dwight E. Bergles

Nature 450, 50-55(1 November 2007)

doi:10.1038/nature06233

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Supplementary Figures

The file contains Supplementary Figures 1-6 with Legends and Supplementary Video Legends.
Supplementary Figures 1-6 and their legends provide evidence for correlation between spontaneous field potentials and inward currents in supporting cells, additional pharmacology of spontaneous extracellular potentials and spontaneous inward currents in supporting cells and inner hair cells, and further characterization of spontaneous optical changes and ATP-elicited Ca2+ transients within the developing cochlea.

Supplementary Video 1a

The file contains Supplementary Video 1a showing time lapse of the unprocessed transmitted light (IR-DIC) signal acquired from a P8 rat organ of Corti illustrates the intrinsic optical changes that spontaneously occur in the supporting cells of Kölliker's organ.

Supplementary Video 1b

The file contains Supplementary Video 1b showing time lapse of Supplementary Video 1 after image subtraction, providing an index of transmitted light change over time.

Supplementary Video 1c

The file contains Supplementary Video 1c showing time lapse of Supplementary Video 1 after image subtraction, thresholding and pseudocoloring.

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