Technology reveals the movements of single cells in early development.
doi:10.1038/7165xiiia
Table of contents
Volume 449 Number 7165 pp947-1088
(this content only available online) indicates content that is available online only
Making the paper: Claudio Stern pxiii
Abstractions pxiii
doi:10.1038/7165xiiib
From the blogosphere pxiii
doi:10.1038/7165xiiic
Top of page
Editorials
The war on want p947
Many 'developing' countries are much more developed than some people think. Their rapid progress should inspire scientists and their institutions to do more to confront global poverty.
doi:10.1038/449947a
Watson's folly p948
Debate about sensitive scientific issues needs to be forthright but not crass.
doi:10.1038/449948a
Going it alone p948
The likely derailment of a US–Indian nuclear deal highlights the limitations of bilateral arrangements.
doi:10.1038/449948b
Top of page
News
Laws under review for fossils on native land p952
Health official speaks out about row over drug critic p952
Fresh light is shed on dispute over diabetes pill.
Meredith Wadman
doi:10.1038/449952b
Air permit blocks Kansas coal plants p953
Global-warming concerns halt construction of power stations.
Jeff Tollefson
doi:10.1038/449953a
Sidelines p954
Europeans forgo US labs p954
Stagnant budget makes American biomedicine less attractive.
Geoff Brumfiel
doi:10.1038/449954b
Italian bioethics committee in uproar p955
Internal conflict hampers debate on stem cells.
Emiliano Feresin
doi:10.1038/449955a
Field trials aim to tackle poverty p957
Little consensus on egg freezing p958
Latest data fail to resolve debate over safety and efficacy.
Brendan Maher
doi:10.1038/449958a
Security issues plague US research p959
National Academies call for commission to limit restrictions.
Eric Hand
doi:10.1038/449959a
Watson suspended over comments on race p960
doi:10.1038/449960a
Greenhouse-gas sensors tower over California p960
doi:10.1038/449960b
Senate retreats from bid to ease stem-cell restrictions p960
doi:10.1038/449960c
Demand made for UK marine-science agency p961
doi:10.1038/449961a
Only six EU nations meet research visa deadline p961
doi:10.1038/449961b
Footprints reveal reptiles showing their age p961
doi:10.1038/449961c
Top of page
Column
Party of OneSpending stalemate p962
As the battle over the US budget drags into autumn, the amount of money available for science is hostage to larger budget disputes. David Goldston explains.
David Goldston
doi:10.1038/449962a
Top of page
Business
Head in the clouds p963
'Cloud computing' is being pitched as a new nirvana for scientists drowning in data. But can it deliver? Eric Hand investigates.
Eric Hand
doi:10.1038/449963a
Top of page
News Features
From wheat to web: Children of the revolution p964
M. S. Swaminathan transformed agriculture in India in the 1960s. Now Daemon Fairless finds him at the heart of another high-tech scheme to help the rural poor.
Daemon Fairless
doi:10.1038/449964a
Geology: Mine Games p968
Under the rubble of war-torn Afghanistan lie natural resources worth billions. Rex Dalton reports from Kabul on the scientists risking their lives to see them developed for the good of the country.
Rex Dalton
doi:10.1038/449968a
Top of page
Correspondence
Old laws stop drugs being used in valuable new ways p972
Transparent frogs show potential of natural world p972
Santiago Castroviejo-Fisher, Ignacio De la Riva & Carles Vilà
doi:10.1038/449972b
Mars needs technology designed for sample return p972
Call for scientists to speak up for human rights p972
Top of page
Commentary
Time to ditch Kyoto p973
Climate policy after 2012, when the Kyoto treaty expires, needs a radical rethink. More of the same won't do, argue Gwyn Prins and Steve Rayner.
Gwyn Prins & Steve Rayner
doi:10.1038/449973a
Top of page
Autumn Books
Harmony of the hemispheres p977
Our brains seem to be finely tuned to music, but of what use are our musical powers and passions?
doi:10.1038/449977a
New in Paperback p977
doi:10.1038/449977b
Using maths to tackle cancer p978
doi:10.1038/449978a
One-man canary p981
doi:10.1038/449981a
Botanists' blues p982
doi:10.1038/449982a
What do mathematicians do? p982
doi:10.1038/449982b
Physical interactions p983
doi:10.1038/449983a
Eras of judgement p985
doi:10.1038/449985a
The power of the mind p988
doi:10.1038/449988a
Top of page
Essay
Science & politicsFishing for certainty p989
Science advisers should have confidence in their data, or risk being undermined by more dogmatic and vociferous stakeholders during the policy-making process.
Andrew A. Rosenberg
doi:10.1038/449989a
Top of page
News and Views
植物科学: 根のパターンを探る
Plant biology: Plumbing the pattern of roots p991
The results of a powerful combination of computer modelling and experimental tests can account for the establishment of gradients of the plant molecule auxin and for major patterning elements in the plant root.
Bruce Veit
doi:10.1038/449991a
日本語要約 | Full Text | PDF (305K)
核物理学: 中性子のドリップライン
Nuclear physics: Neutrons cross the line p992
For most atomic nuclei, the maximum number of neutrons that can be bound is unknown. The discovery of two neutron-rich nuclei — and the confirmed absence of others — might help solve this conundrum.
Paul-Henri Heenen
doi:10.1038/449992a
日本語要約 | Full Text | PDF (187K)
癌: 混合カクテル
Cancer: Mixing cocktails p993
A major hurdle in treating cancer is that tumour cells acquire drug resistance. To overcome this problem, one strategy might be to fine-tune the right mixture of drugs that target specific molecules.
Charles L. Sawyers
doi:10.1038/449993a
50 & 100 Years Ago p995
doi:10.1038/449995a
個体群生態学: 群れでの生活と空腹なライオン
Population ecology: Group living and hungry lions p996
Ecologists have necessarily had to simplify matters in looking at predator–prey dynamics. Study of a situation in which predator and prey live in groups reveals that a key process was previously overlooked.
Tim Coulson
doi:10.1038/449996a
日本語要約 | Full Text | PDF (217K)
アト秒物理学: ちらっと見えた電子の動態
Attophysics: At a glance p997
Measurements on the attosecond timescale had been limited to the dynamics of electrons in an atomic gas. But a record has now been set in a quite different context — the photoemission of electrons from a surface.
David M. Villeneuve
doi:10.1038/449997a
日本語要約 | Full Text | PDF (214K)
生化学: 無頓着なシャペロン
Biochemistry: Indifferent chaperones p999
How do nonspecific enzymes that help to correct RNA folding identify misfolded structures among similar, properly folded RNAs? It seems that careful discrimination has little to do with it.
Eckhard Jankowsky
doi:10.1038/449999a
日本語要約 | Full Text | PDF (266K)
環境科学: 協同的に働く栄養素
Environmental science: Nutrients in synergy p1000
A literature meta-analysis of the effects of nitrogen and phosphorus on plant growth prompts a thought-provoking inference — that the supply of, and demand for, these nutrients are usually in close balance.
Eric A. Davidson & Robert W. Howarth
doi:10.1038/4491000a
日本語要約 | Full Text | PDF (289K)
Top of page
Articles
マーカー遺伝子Lgr5による小腸および結腸の幹細胞の同定
Identification of stem cells in small intestine and colon by marker gene Lgr5 p1003
Nick Barker, Johan H. van Es, Jeroen Kuipers, Pekka Kujala, Maaike van den Born, Miranda Cozijnsen, Andrea Haegebarth, Jeroen Korving, Harry Begthel, Peter J. Peters & Hans Clevers
doi:10.1038/nature06196
日本語要約 | Full Text | PDF (3,829K) | Supplementary information
根の成長を導くオーキシン最大濃度と勾配の形成にはオーキシン輸送だけで十分である
Auxin transport is sufficient to generate a maximum and gradient guiding root growth p1008
Verônica A. Grieneisen, Jian Xu, Athanasius F. M. Marée, Paulien Hogeweg & Ben Scheres
doi:10.1038/nature06215
日本語要約 | Full Text | PDF (1,602K) | Supplementary information
正しく折りたたまれたRNAと誤って折りたたまれたRNAのDEADボックス型シャペロンによる速度論的再分布
Kinetic redistribution of native and misfolded RNAs by a DEAD-box chaperone p1014
Hari Bhaskaran & Rick Russell
doi:10.1038/nature06235
Top of page
Letters
土星A環の微衛星帯
A belt of moonlets in Saturn's A ring p1019
Miodrag Srem
evi
,
Jürgen Schmidt,
Heikki Salo,
Martin Sei
,
Frank Spahn
&
Nicole Albers
doi:10.1038/nature06224
40Mgと42Alの発見は中性子のドリップラインがより重い同位体に向かう傾向を示す
Discovery of 40Mg and 42Al suggests neutron drip-line slant towards heavier isotopes p1022
T. Baumann,
A. M. Amthor,
D. Bazin,
B. A. Brown,
C. M. Folden III,
A. Gade,
T. N. Ginter,
M. Hausmann,
M. Mato
,
D. J. Morrissey,
M. Portillo,
A. Schiller,
B. M. Sherrill,
A. Stolz,
O. B. Tarasov
&
M. Thoennessen
doi:10.1038/nature06213
日本語要約 | Full Text | PDF (495K)
超固体転移の徴候と考えられる熱容量変化
Probable heat capacity signature of the supersolid transition p1025
X. Lin, A. C. Clark & M. H. W. Chan
doi:10.1038/nature06228
凝縮物質におけるアト秒分光法
Attosecond spectroscopy in condensed matter p1029
A. L. Cavalieri,
N. Müller,
Th. Uphues,
V. S. Yakovlev,
A. Baltuka,
B. Horvath,
B. Schmidt,
L. Blümel,
R. Holzwarth,
S. Hendel,
M. Drescher,
U. Kleineberg,
P. M. Echenique,
R. Kienberger,
F. Krausz
&
U. Heinzmann
doi:10.1038/nature06229
質量分析のためのクラスレートナノ構造体
Clathrate nanostructures for mass spectrometry p1033
Trent R. Northen, Oscar Yanes, Michael T. Northen, Dena Marrinucci, Winnie Uritboonthai, Junefredo Apon, Stephen L. Golledge, Anders Nordström & Gary Siuzdak
doi:10.1038/nature06195
海洋島火山活動における非平衡脱ガスとヘリウムの始原的供給源
Non-equilibrium degassing and a primordial source for helium in ocean-island volcanism p1037
Helge M. Gonnermann & Sujoy Mukhopadhyay
doi:10.1038/nature06240
群れ形成が捕食者-被食者動態を安定させる
Group formation stabilizes predator–prey dynamics p1041
John M. Fryxell, Anna Mosser, Anthony R. E. Sinclair & Craig Packer
doi:10.1038/nature06177
ワタリアホウドリ、マルハナバチ、シカにおけるレヴィ・フライト的探索パターンの再検討
Revisiting Lévy flight search patterns of wandering albatrosses, bumblebees and deer p1044
Andrew M. Edwards, Richard A. Phillips, Nicholas W. Watkins, Mervyn P. Freeman, Eugene J. Murphy, Vsevolod Afanasyev, Sergey V. Buldyrev, M. G. E. da Luz, E. P. Raposo, H. Eugene Stanley & Gandhimohan M. Viswanathan
doi:10.1038/nature06199
羊膜動物の原始線条は原腸形成前の上皮細胞のインターカレーションによって決定される
The amniote primitive streak is defined by epithelial cell intercalation before gastrulation p1049
Octavian Voiculescu, Federica Bertocchini, Lewis Wolpert, Ray E. Keller & Claudio D. Stern
doi:10.1038/nature06211
日本語要約 | Full Text | PDF (1,152K) | Supplementary information
PLETHORAタンパク質はシロイヌナズナの根発生に関する濃度依存的な主要調節因子として働く
PLETHORA proteins as dose-dependent master regulators of Arabidopsis root development p1053
Carla Galinha, Hugo Hofhuis, Marijn Luijten, Viola Willemsen, Ikram Blilou, Renze Heidstra & Ben Scheres
doi:10.1038/nature06206
日本語要約 | Full Text | PDF (1,043K) | Supplementary information
プリンを介したシグナル伝達が目の発生を引き起こす
Purine-mediated signalling triggers eye development p1058
Karine Massé, Surinder Bhamra, Robert Eason, Nicholas Dale & Elizabeth A. Jones
doi:10.1038/nature06189
日本語要約 | Full Text | PDF (1,326K) | Supplementary information
レトロマー積み荷認識複合体の機能的構造
Functional architecture of the retromer cargo-recognition complex p1063
Aitor Hierro, Adriana L. Rojas, Raul Rojas, Namita Murthy, Grégory Effantin, Andrey V. Kajava, Alasdair C. Steven, Juan S. Bonifacino & James H. Hurley
doi:10.1038/nature06216
日本語要約 | Full Text | PDF (2,237K) | Supplementary information
細胞周期の進行と遺伝子発現のH2A脱ユビキチン化による調節
Regulation of cell cycle progression and gene expression by H2A deubiquitination p1068
Heui-Yun Joo, Ling Zhai, Chunying Yang, Shuyi Nie, Hediye Erdjument-Bromage, Paul Tempst, Chenbei Chang & Hengbin Wang
doi:10.1038/nature06256
Rasが仲介するエピジェネティックサイレンシングに必要とされる精巧な経路
An elaborate pathway required for Ras-mediated epigenetic silencing p1073
Claude Gazin, Narendra Wajapeyee, Stephane Gobeil, Ching-Man Virbasius & Michael R. Green
doi:10.1038/nature06251
アポ型マルトース結合タンパク質の開状態から閉状態への転移の常磁性NMRによる観察
Open-to-closed transition in apo maltose-binding protein observed by paramagnetic NMR p1078
Chun Tang, Charles D. Schwieters & G. Marius Clore
doi:10.1038/nature06232
日本語要約 | Full Text | PDF (1,048K) | Supplementary information
Top of page
Postdocs and Students
Career View
Naturejobs
ProspectProspects p1083
Similar postdoc glut, different country.
Gene Russo
doi:10.1038/nj7165-1083a
Postdocs and Students
Scientists to spare p1084
After boosting its number of postdocs by thousands, Japan is dealing with a major researcher glut. Heidi Ledford reports.
Heidi Ledford
doi:10.1038/nj7165-1084a
Career View
Nancy Andrews, vice-chancellor and dean, Duke University School of Medicine, Durham, North Carolina p1086
Nancy Andrews becomes one of only a handful of women to become dean at a top medical school.
Virginia Gewin
doi:10.1038/nj7165-1086a
Hopes for growth in Spain p1086
A call for research growth in Spain.
José Prieto
doi:10.1038/nj7165-1086b
Metamorphosis p1086
Change is coming. I hope I'm ready.
Maria Ocampo-Hafalla
doi:10.1038/nj7165-1086c
