Editorials

The war on want p947

Many 'developing' countries are much more developed than some people think. Their rapid progress should inspire scientists and their institutions to do more to confront global poverty.

doi:10.1038/449947a

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Watson's folly p948

Debate about sensitive scientific issues needs to be forthright but not crass.

doi:10.1038/449948a

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Going it alone p948

The likely derailment of a US–Indian nuclear deal highlights the limitations of bilateral arrangements.

doi:10.1038/449948b

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Research Highlights

Research highlights p950

doi:10.1038/449950a

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Journal Club

Journal club p951

Minhaeng Cho

doi:10.1038/449951a

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News

Laws under review for fossils on native land p952

Questions raised over fate of non-human remains.

Rex Dalton

doi:10.1038/449952a

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Health official speaks out about row over drug critic p952

Fresh light is shed on dispute over diabetes pill.

Meredith Wadman

doi:10.1038/449952b

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Air permit blocks Kansas coal plants p953

Global-warming concerns halt construction of power stations.

Jeff Tollefson

doi:10.1038/449953a

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Sidelines p954

Scribbles on the margins of science.

doi:10.1038/449954a

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Europeans forgo US labs p954

Stagnant budget makes American biomedicine less attractive.

Geoff Brumfiel

doi:10.1038/449954b

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Italian bioethics committee in uproar p955

Internal conflict hampers debate on stem cells.

Emiliano Feresin

doi:10.1038/449955a

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Field trials aim to tackle poverty p957

Declan Butler

doi:10.1038/449957a

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Little consensus on egg freezing p958

Latest data fail to resolve debate over safety and efficacy.

Brendan Maher

doi:10.1038/449958a

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Security issues plague US research p959

National Academies call for commission to limit restrictions.

Eric Hand

doi:10.1038/449959a

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Watson suspended over comments on race p960

doi:10.1038/449960a

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Greenhouse-gas sensors tower over California p960

doi:10.1038/449960b

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Senate retreats from bid to ease stem-cell restrictions p960

doi:10.1038/449960c

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Demand made for UK marine-science agency p961

doi:10.1038/449961a

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Only six EU nations meet research visa deadline p961

doi:10.1038/449961b

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Footprints reveal reptiles showing their age p961

doi:10.1038/449961c

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Column

Spending stalemate p962

As the battle over the US budget drags into autumn, the amount of money available for science is hostage to larger budget disputes. David Goldston explains.

David Goldston

doi:10.1038/449962a

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Business

Head in the clouds p963

'Cloud computing' is being pitched as a new nirvana for scientists drowning in data. But can it deliver? Eric Hand investigates.

Eric Hand

doi:10.1038/449963a

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News Features

From wheat to web: Children of the revolution p964

M. S. Swaminathan transformed agriculture in India in the 1960s. Now Daemon Fairless finds him at the heart of another high-tech scheme to help the rural poor.

doi:10.1038/449964a

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Geology: Mine Games p968

Under the rubble of war-torn Afghanistan lie natural resources worth billions. Rex Dalton reports from Kabul on the scientists risking their lives to see them developed for the good of the country.

doi:10.1038/449968a

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Correspondence

Old laws stop drugs being used in valuable new ways p972

S. Paul Berger

doi:10.1038/449972a

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Transparent frogs show potential of natural world p972

Santiago Castroviejo-Fisher, Ignacio De la Riva & Carles Vilà

doi:10.1038/449972b

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Mars needs technology designed for sample return p972

John Whitehead

doi:10.1038/449972c

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Call for scientists to speak up for human rights p972

Juan C. Gallardo

doi:10.1038/449972d

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Commentary

Time to ditch Kyoto p973

Climate policy after 2012, when the Kyoto treaty expires, needs a radical rethink. More of the same won't do, argue Gwyn Prins and Steve Rayner.

doi:10.1038/449973a

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Autumn Books

Harmony of the hemispheres p977

Our brains seem to be finely tuned to music, but of what use are our musical powers and passions?

Laura Garwin reviews Musicophilia: Tales of Music and the Brain by Oliver Sacks and This is Your Brain on Music: Understanding a Human Obsession by Daniel Levitin

doi:10.1038/449977a

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New in Paperback p977

doi:10.1038/449977b

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Using maths to tackle cancer p978

Robert A. Weinberg reviews Dynamics of Cancer: Incidence, Inheritance, and Evolution by Steven A. Frank

doi:10.1038/449978a

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One-man canary p981

Andy Meharg reviews Suffer and Survive: The Extreme Life of J. S. Haldane by Martin Goodman

doi:10.1038/449981a

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Botanists' blues p982

Philip Ball reviews Nature's Palette: The Science of Plant Color by David Lee

doi:10.1038/449982a

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What do mathematicians do? p982

Donal O'Shea reviews How Mathematicians Think: Using Ambiguity, Contradiction, and Paradox to Create Mathematics by William Byers and The Mathematician's Brain: A Personal Tour Through the Essentials of Mathematics and Some of the Great Minds Behind Them by David Ruelle and The Mind of the Mathematician by Michael Fitzgerald & Ioan James

doi:10.1038/449982b

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Physical interactions p983

David Harris reviews Structures of Scientific Collaboration by Wesley Shrum, Joel Genuth & Ivan Chompalov

doi:10.1038/449983a

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Eras of judgement p985

Theodore M. Porter reviews Objectivity by Lorraine Daston & Peter Galison

doi:10.1038/449985a

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The power of the mind p988

Janna Levin reviews Ghost: A Novel by Alan Lightman

doi:10.1038/449988a

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Essay

Fishing for certainty p989

Science advisers should have confidence in their data, or risk being undermined by more dogmatic and vociferous stakeholders during the policy-making process.

Andrew A. Rosenberg

doi:10.1038/449989a

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News and Views

Plant biology: Plumbing the pattern of roots p991

The results of a powerful combination of computer modelling and experimental tests can account for the establishment of gradients of the plant molecule auxin and for major patterning elements in the plant root.

Bruce Veit

doi:10.1038/449991a

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Nuclear physics: Neutrons cross the line p992

For most atomic nuclei, the maximum number of neutrons that can be bound is unknown. The discovery of two neutron-rich nuclei — and the confirmed absence of others — might help solve this conundrum.

Paul-Henri Heenen

doi:10.1038/449992a

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Cancer: Mixing cocktails p993

A major hurdle in treating cancer is that tumour cells acquire drug resistance. To overcome this problem, one strategy might be to fine-tune the right mixture of drugs that target specific molecules.

Charles L. Sawyers

doi:10.1038/449993a

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50 & 100 Years Ago p995

doi:10.1038/449995a

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Population ecology: Group living and hungry lions p996

Ecologists have necessarily had to simplify matters in looking at predator–prey dynamics. Study of a situation in which predator and prey live in groups reveals that a key process was previously overlooked.

Tim Coulson

doi:10.1038/449996a

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Attophysics: At a glance p997

Measurements on the attosecond timescale had been limited to the dynamics of electrons in an atomic gas. But a record has now been set in a quite different context — the photoemission of electrons from a surface.

David M. Villeneuve

doi:10.1038/449997a

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Biochemistry: Indifferent chaperones p999

How do nonspecific enzymes that help to correct RNA folding identify misfolded structures among similar, properly folded RNAs? It seems that careful discrimination has little to do with it.

Eckhard Jankowsky

doi:10.1038/449999a

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Environmental science: Nutrients in synergy p1000

A literature meta-analysis of the effects of nitrogen and phosphorus on plant growth prompts a thought-provoking inference — that the supply of, and demand for, these nutrients are usually in close balance.

Eric A. Davidson & Robert W. Howarth

doi:10.1038/4491000a

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Articles

Identification of stem cells in small intestine and colon by marker gene Lgr5 p1003

Nick Barker, Johan H. van Es, Jeroen Kuipers, Pekka Kujala, Maaike van den Born, Miranda Cozijnsen, Andrea Haegebarth, Jeroen Korving, Harry Begthel, Peter J. Peters & Hans Clevers

doi:10.1038/nature06196

Abstract | Full Text | PDF (3,829K) | Supplementary information

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Auxin transport is sufficient to generate a maximum and gradient guiding root growth p1008

Verônica A. Grieneisen, Jian Xu, Athanasius F. M. Marée, Paulien Hogeweg & Ben Scheres

doi:10.1038/nature06215

Abstract | Full Text | PDF (1,602K) | Supplementary information

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Kinetic redistribution of native and misfolded RNAs by a DEAD-box chaperone p1014

Hari Bhaskaran & Rick Russell

doi:10.1038/nature06235

Abstract | Full Text | PDF (684K) | Supplementary information

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Letters

A belt of moonlets in Saturn's A ring p1019

Miodrag Sremevi, Jürgen Schmidt, Heikki Salo, Martin Sei, Frank Spahn & Nicole Albers

doi:10.1038/nature06224

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Discovery of ⁴⁰Mg and ⁴²Al suggests neutron drip-line slant towards heavier isotopes p1022

T. Baumann, A. M. Amthor, D. Bazin, B. A. Brown, C. M. Folden III, A. Gade, T. N. Ginter, M. Hausmann, M. Mato, D. J. Morrissey, M. Portillo, A. Schiller, B. M. Sherrill, A. Stolz, O. B. Tarasov & M. Thoennessen

doi:10.1038/nature06213

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Probable heat capacity signature of the supersolid transition p1025

X. Lin, A. C. Clark & M. H. W. Chan

doi:10.1038/nature06228

First paragraph | Full Text | PDF (466K) | Supplementary information

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Attosecond spectroscopy in condensed matter p1029

A. L. Cavalieri, N. Müller, Th. Uphues, V. S. Yakovlev, A. Baltuka, B. Horvath, B. Schmidt, L. Blümel, R. Holzwarth, S. Hendel, M. Drescher, U. Kleineberg, P. M. Echenique, R. Kienberger, F. Krausz & U. Heinzmann

doi:10.1038/nature06229

First paragraph | Full Text | PDF (612K) | Supplementary information

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Clathrate nanostructures for mass spectrometry p1033

Trent R. Northen, Oscar Yanes, Michael T. Northen, Dena Marrinucci, Winnie Uritboonthai, Junefredo Apon, Stephen L. Golledge, Anders Nordström & Gary Siuzdak

doi:10.1038/nature06195

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Non-equilibrium degassing and a primordial source for helium in ocean-island volcanism p1037

Helge M. Gonnermann & Sujoy Mukhopadhyay

doi:10.1038/nature06240

First paragraph | Full Text | PDF (331K) | Supplementary information

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Group formation stabilizes predator–prey dynamics p1041

John M. Fryxell, Anna Mosser, Anthony R. E. Sinclair & Craig Packer

doi:10.1038/nature06177

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Revisiting Lévy flight search patterns of wandering albatrosses, bumblebees and deer p1044

Andrew M. Edwards, Richard A. Phillips, Nicholas W. Watkins, Mervyn P. Freeman, Eugene J. Murphy, Vsevolod Afanasyev, Sergey V. Buldyrev, M. G. E. da Luz, E. P. Raposo, H. Eugene Stanley & Gandhimohan M. Viswanathan

doi:10.1038/nature06199

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The amniote primitive streak is defined by epithelial cell intercalation before gastrulation p1049

Octavian Voiculescu, Federica Bertocchini, Lewis Wolpert, Ray E. Keller & Claudio D. Stern

doi:10.1038/nature06211

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PLETHORA proteins as dose-dependent master regulators of Arabidopsis root development p1053

Carla Galinha, Hugo Hofhuis, Marijn Luijten, Viola Willemsen, Ikram Blilou, Renze Heidstra & Ben Scheres

doi:10.1038/nature06206

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Purine-mediated signalling triggers eye development p1058

Karine Massé, Surinder Bhamra, Robert Eason, Nicholas Dale & Elizabeth A. Jones

doi:10.1038/nature06189

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Functional architecture of the retromer cargo-recognition complex p1063

Aitor Hierro, Adriana L. Rojas, Raul Rojas, Namita Murthy, Grégory Effantin, Andrey V. Kajava, Alasdair C. Steven, Juan S. Bonifacino & James H. Hurley

doi:10.1038/nature06216

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Regulation of cell cycle progression and gene expression by H2A deubiquitination p1068

Heui-Yun Joo, Ling Zhai, Chunying Yang, Shuyi Nie, Hediye Erdjument-Bromage, Paul Tempst, Chenbei Chang & Hengbin Wang

doi:10.1038/nature06256

First paragraph | Full Text | PDF (497K) | Supplementary information

An elaborate pathway required for Ras-mediated epigenetic silencing p1073

Claude Gazin, Narendra Wajapeyee, Stephane Gobeil, Ching-Man Virbasius & Michael R. Green

doi:10.1038/nature06251

First paragraph | Full Text | PDF (399K) | Supplementary information

Open-to-closed transition in apo maltose-binding protein observed by paramagnetic NMR p1078

Chun Tang, Charles D. Schwieters & G. Marius Clore

doi:10.1038/nature06232

First paragraph | Full Text | PDF (1,048K) | Supplementary information

Naturejobs

Prospects p1083

Similar postdoc glut, different country.

Gene Russo

doi:10.1038/nj7165-1083a

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Scientists to spare p1084

After boosting its number of postdocs by thousands, Japan is dealing with a major researcher glut. Heidi Ledford reports.

Heidi Ledford

doi:10.1038/nj7165-1084a

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Nancy Andrews, vice-chancellor and dean, Duke University School of Medicine, Durham, North Carolina p1086

Nancy Andrews becomes one of only a handful of women to become dean at a top medical school.

Virginia Gewin

doi:10.1038/nj7165-1086a

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Hopes for growth in Spain p1086

A call for research growth in Spain.

José Prieto

doi:10.1038/nj7165-1086b

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Metamorphosis p1086

Change is coming. I hope I'm ready.

Maria Ocampo-Hafalla

doi:10.1038/nj7165-1086c

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Futures

The patter of tiny feet p1088

A blast from the past.

Guy Riddihough

doi:10.1038/4491088a

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