TABLE 1
From the following article:
Mark J. Pallen & Brendan W. Wren
Nature 449, 835-842(18 October 2007)
doi:10.1038/nature06248
Table 1. Examples of mobile genetic elements that encode virulence factors and are present in human pathogens.
| Type of mobile element | Pathogen | Virulence factor |
|---|---|---|
∗Involved in intracellular survival. | ||
| Plasmid | Bacillus anthracis | Anthrax toxin |
| Clostridium tetani | Tetanus toxin | |
| Enterotoxigenic Escherichia coli | Heat-stabile toxin, heat-labile toxin and fimbriae | |
| Mycobacterium ulcerans | Polyketide toxin | |
| Salmonella enterica serovar Typhimurium | SpvR, SpvA, SpvB, SpvC and SpvD proteins∗ | |
| Shigella spp. | Type III secretion system | |
| Staphylococcus aureus | Exfoliatin B | |
| Pathogenic Yersinia spp. | Type III secretion system | |
| Prophage | Corynebacterium diphtheriae | Diphtheria toxin |
| Enterohaemorrhagic E. coli | Shiga toxin and type III secretion effectors | |
| S. aureus | Staphylococcal enterotoxin A, exfoliatin A and Panton–Valentine leukocidin | |
| Streptococcus pyogenes | Streptococcal pyrogenic exotoxins, DNases and streptococcal phospholipase A2 (Sla) | |
| Vibrio cholerae | Cholera toxin | |
| Pathogenicity island | Clostridium difficile | Clostridial enterotoxin and clostridial cytotoxin |
| Enteropathogenic and enterohaemorrhagic E. coli | Type III secretion system | |
| Uropathogenic E. coli | Fimbriae, iron-uptake systems, the capsular polysaccharide and  -haemolysin | |
| Helicobacter pylori | Cag antigen | |
| S. enterica | Type III secretion systems | |
| S. aureus | Toxic-shock toxin, staphylococcal enterotoxin B, enterotoxin C, enterotoxin K and enterotoxin L | |
