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Nature 449, 721-725 (30 September 2007) | doi:10.1038/nature06185;
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Organic Chemistry
- Praj Matrix - Praj Industries Ltd
- Pune, Maharashtra Pune-411021 India
Gastrointestinal Pathologist
- Brigham and Women's Hospital
- Boston, MA
Phagocyte-derived catecholamines enhance acute inflammatory injury
It is becoming increasingly clear that the autonomic nervous system and the immune system demonstrate cross-talk during inflammation by means of sympathetic and parasympathetic pathways. We investigated whether phagocytes are capable of de novo production of catecholamines, suggesting an autocrine/paracrine self-regulatory mechanism by catecholamines during inflammation, as has been described for lymphocytes.
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