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Editorials

Kill king corn p637

Biofuels need new technology, new agronomy and new politics if they are not to do more harm than good.

doi:10.1038/449637a


A matter of trust p637

Social scientists studying electronic interactions must take the lead on preserving data security.

doi:10.1038/449637b


How to be good? p638

Mentoring and training for ethical behaviour aren't all they're cracked up to be.

doi:10.1038/449638a


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Research Highlights

Research highlights p640

doi:10.1038/449640a


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Journal Club

Journal club p641

Francis Albarede

doi:10.1038/449641a


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News

Biologists claim Nobel prize with a knock-out p642

Architects of mutant mice are rewarded for their work.

Alison Abbott

doi:10.1038/449642a


The physics prize inside the iPod p643

Geoff Brumfiel

doi:10.1038/449643a


Immigration institute provokes outcry from social scientists p643

French plan to research integration meets with disapproval.

Declan Butler

doi:10.1038/449643b


Data sharing threatens privacy p644

Analyses of personal information raise spectre of Big Brother.

Declan Butler

doi:10.1038/449644a


Doctors not to blame over HIV infection by tainted blood p644

Canadian court acquits medics accused of negligence.

Meredith Wadman

doi:10.1038/449644b


Sidelines p645

doi:10.1038/449645a


Congress grills officials over biosafety boom p646

Is bioterror research really making life safer?

Ewen Callaway

doi:10.1038/449646a


Europe ponders restrictions on life sciences p646

Plan for two-tier publications gets cool reception.

Daniel Cressey

doi:10.1038/449646b


Doubts raised over stem-cell marker p647

Protein may not be accurate in adult samples.

Heidi Ledford

doi:10.1038/449647a


Weapons of war scoop spoof Nobels p648

From sword swallowing to a 'gay' bomb.

Steve Nadis

doi:10.1038/449648a


Panel issues warning over mineral market tremors p648

Strategic supply should be monitored, say US academics.

Eric Hand

doi:10.1038/449648b


University of California fined over security breach p649

doi:10.1038/449649a


Blueprint drawn up for Britain's science spending p649

doi:10.1038/449649b


Council of Europe votes against creationist teaching p649

doi:10.1038/449649c


Conservationists spot flaws in plan to save owl p649

doi:10.1038/449649d


India gets high-security lab for human diseases p649

doi:10.1038/449649e


Hooke online offers minute details of Royal Society p649

doi:10.1038/449649f


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Corrections

Correction p649

doi:10.1038/449649g


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Business

Patent crunch pending p651

Drug makers are fighting a rear-guard action against patent laws that are before the US Congress. Meredith Wadman reports.

Meredith Wadman

doi:10.1038/449651a


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News Features

Biofuel: The little shrub that could — maybe p652

India, like many countries, has high hopes for jatropha as a biofuel source, but little is known about how to make it a successful crop. Daemon Fairless digs for the roots of a new enthusiasm.

doi:10.1038/449652a


Non-proliferation: School of Nukes p656

How do nuclear inspectors know when all is not as they are told? Geoff Brumfiel joins some inspectors-in-training as they learn the ropes at the Los Alamos National Laboratory.

doi:10.1038/449656a



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Correspondence

Plagiarism? No, we're just borrowing better English p658

Ihsan Yilmaz

doi:10.1038/449658a


Plagiarism: text-matching program offers an answer p658

John Bechhoefer

doi:10.1038/449658b


Need to strike balance with industry–academia rules p658

Andrew Leuchter & Gerald S. Levey

doi:10.1038/449658c


Biosafety risk in health lab move to central London p658

Ellen Nisbet

doi:10.1038/449658d


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Books and Arts

An incomparable life p659

Exceptional intellect and creativity made Ernst Mayr the last century's greatest evolutionary biologist.

Jared Diamond reviews Ornithology, Evolution, and Philosophy: The Life and Science of Ernst Mayr 1904–2005 by Jürgen Haffer

doi:10.1038/449659a


The dark side of cancer research p660

Daniel S. Greenberg reviews The Secret History of the War on Cancer by Devra Davis

doi:10.1038/449660a


Promoting capitalism over Kyoto p661

Jonathon Porritt reviews Break Through: From the Death of Environmentalism to the Politics of Possibility by Michael Shellenberger & Ted Nordhaus

doi:10.1038/449661a


Academic snakes and ladders p662

Pamela A. Silver reviews The Chicago Guide to Landing a Job in Academic Biology by C. Ray Chandler, Lorne M. Wolfe & Daniel E. L. Promislow

doi:10.1038/449662a


Event: Experiment-a-thon p662

Matt Brown reviews

doi:10.1038/449662b


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Essays

Science & Politics: When ministers are well primed p663

Enthusing and informing government members about science can have surprising and gratifying results.

Hans Wigzell

doi:10.1038/449663a


Fifty years of hopes and fears p664

Atomic energy was cutting edge when the Windscale fire showed the world the effects of a nuclear accident. Fifty years on, we have more innovative ways to generate electricity.

Walt Patterson

doi:10.1038/449664a

See also: Editor's summary


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News and Views

Linguistics: An invisible hand p665

Quantitative relationships between how frequently a word is used and how rapidly it changes over time raise intriguing questions about the way individual behaviours determine large-scale linguistic and cultural change.

W. Tecumseh Fitch

doi:10.1038/449665a

See also: Editor's summary


Organic chemistry: Zippier synthesis in water p667

Complex toxin molecules are the ultimate challenge for organic chemists — even successful syntheses often involve an impractical number of steps. A biologically inspired reaction might simplify things.

Masayuki Inoue

doi:10.1038/449667a


Laser physics: A phase it's going through p669

When we observe laser light, we typically measure its intensity, and so wave amplitude. The phase, which encodes further details of the laser's internal workings, was obscure — but fresh light is being shed on it.

David S. Citrin

doi:10.1038/449669a

See also: Editor's summary


Cancer: Micromanagement of metastasis p671

Although they were discovered only in the early 1990s, many regulatory functions of microRNAs — naturally occurring short RNA sequences — have already been reported. The latest news is that they mediate cancer spread.

Patricia S. Steeg

doi:10.1038/449671a

See also: Editor's summary


Evolutionary genetics: Making the most of redundancy p673

Single genes, chromosomal regions and even entire genomes can undergo duplication. What good can come of these extra copies? Evolution seems to use several tricks to take advantage of the situation.

Edward J. Louis

doi:10.1038/449673a

See also: Editor's summary


Solid-state physics: Response with a twist p674

The behaviour of ferromagnetic and ferroelectric materials in a magnetic or electric field makes them easy to spot. But for their more recently discovered counterpart, ferrotoroidic materials, things become complex.

Karin M. Rabe

doi:10.1038/449674a

See also: Editor's summary


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Articles

Gene duplication and the adaptive evolution of a classic genetic switch p677

Chris Todd Hittinger & Sean B. Carroll

doi:10.1038/nature06151

See also: Editor's summary | News and Views by Louis


Tumour invasion and metastasis initiated by microRNA-10b in breast cancer p682

Li Ma, Julie Teruya-Feldstein & Robert A. Weinberg

doi:10.1038/nature06174

See also: Editor's summary | News and Views by Steeg


A histone H3 lysine 27 demethylase regulates animal posterior development p689

Fei Lan, Peter E. Bayliss, John L. Rinn, Johnathan R. Whetstine, Jordon K. Wang, Shuzhen Chen, Shigeki Iwase, Roman Alpatov, Irina Issaeva, Eli Canaani, Thomas M. Roberts, Howard Y. Chang & Yang Shi

doi:10.1038/nature06192


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Letters

Association of the jets of Enceladus with the warmest regions on its south-polar fractures p695

Joseph N. Spitale & Carolyn C. Porco

doi:10.1038/nature06217

See also: Editor's summary


Phase-resolved measurements of stimulated emission in a laser p698

Josef Kröll, Juraj Darmo, Sukhdeep S. Dhillon, Xavier Marcadet, Michel Calligaro, Carlo Sirtori & Karl Unterrainer

doi:10.1038/nature06208

See also: Editor's summary | News and Views by Citrin


Observation of ferrotoroidic domains p702

Bas B. Van Aken, Jean-Pierre Rivera, Hans Schmid & Manfred Fiebig

doi:10.1038/nature06139

See also: Editor's summary | News and Views by Rabe


Isotopic evidence for Mesoarchaean anoxia and changing atmospheric sulphur chemistry p706

James Farquhar, Marc Peters, David T. Johnston, Harald Strauss, Andrew Masterson, Uwe Wiechert & Alan J. Kaufman

doi:10.1038/nature06202


Attribution of observed surface humidity changes to human influence p710

Katharine M. Willett, Nathan P. Gillett, Philip D. Jones & Peter W. Thorne

doi:10.1038/nature06207

See also: Editor's summary


Quantifying the evolutionary dynamics of language p713

Erez Lieberman, Jean-Baptiste Michel, Joe Jackson, Tina Tang & Martin A. Nowak

doi:10.1038/nature06137

See also: Editor's summary | News and Views by Fitch


Frequency of word-use predicts rates of lexical evolution throughout Indo-European history p717

Mark Pagel, Quentin D. Atkinson & Andrew Meade

doi:10.1038/nature06176

See also: Editor's summary | News and Views by Fitch


Phagocyte-derived catecholamines enhance acute inflammatory injury p721

Michael A. Flierl, Daniel Rittirsch, Brian A. Nadeau, Anthony J. Chen, J. Vidya Sarma, Firas S. Zetoune, Stephanie R. McGuire, Rachel P. List, Danielle E. Day, L. Marco Hoesel, Hongwei Gao, Nico Van Rooijen, Markus S. Huber-Lang, Richard R. Neubig & Peter A. Ward

doi:10.1038/nature06185

See also: Editor's summary


Mechanism of chloride interaction with neurotransmitter:sodium symporters p726

Elia Zomot, Annie Bendahan, Matthias Quick, Yongfang Zhao, Jonathan A. Javitch & Baruch I. Kanner

doi:10.1038/nature06133

See also: Editor's summary


UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development p731

Karl Agger, Paul A. C. Cloos, Jesper Christensen, Diego Pasini, Simon Rose, Juri Rappsilber, Irina Issaeva, Eli Canaani, Anna Elisabetta Salcini & Kristian Helin

doi:10.1038/nature06145


Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4 p735

Takayuki Obita, Suraj Saksena, Sara Ghazi-Tabatabai, David J. Gill, Olga Perisic, Scott D. Emr & Roger L. Williams

doi:10.1038/nature06171


ESCRT-III recognition by VPS4 ATPases p740

Melissa D. Stuchell-Brereton, Jack J. Skalicky, Collin Kieffer, Mary Anne Karren, Sanaz Ghaffarian & Wesley I. Sundquist

doi:10.1038/nature06172


Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway p745

Matthias John, Rainer Constien, Akin Akinc, Michael Goldberg, Young-Ah Moon, Martina Spranger, Philipp Hadwiger, Jürgen Soutschek, Hans-Peter Vornlocher, Muthiah Manoharan, Markus Stoffel, Robert Langer, Daniel G. Anderson, Jay D. Horton, Victor Koteliansky & David Bumcrot

doi:10.1038/nature06179

See also: Editor's summary


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Corrigendum

Southern Ocean sea-ice extent, productivity and iron flux over the past eight glacial cycles p748

E. W. Wolff, H. Fischer, F. Fundel, U. Ruth, B. Twarloh, G. C. Littot, R. Mulvaney, R. Röthlisberger, M. de Angelis, C. F. Boutron, M. Hansson, U. Jonsell, M. A. Hutterli, F. Lambert, P. Kaufmann, B. Stauffer, T. F. Stocker, J. P. Steffensen, M. Bigler, M. L. Siggaard-Andersen, R. Udisti, S. Becagli, E. Castellano, M. Severi, D. Wagenbach, C. Barbante, P. Gabrielli & V. Gaspari

doi:10.1038/nature06271


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Naturejobs

Prospect

Prospects p749

Working from home can be tough, no matter what the profession.

Gene Russo

doi:10.1038/nj7163-749a


Special Report

Freedom of the skies p750

For astronomers looking for maximum independence, working from home is an option. But it has its challenges. Genevive Bjorn reports.

Genevive Bjorn

doi:10.1038/nj7163-750a


Career View

Elena Shevchenko, scientist, & Elena Rozhkova, assistant scientist, Center for Nanoscale Materials, Argonne National Laboratory, Illinois p752

Nanotech expert and bioorganic chemist move to Argonne to collaborate.

Virginia Gewin

doi:10.1038/nj7163-752a


Awards for South Africa's best p752

Mentors receive accolades in South Africa.

Paul Smaglik

doi:10.1038/nj7163-752b


Perseverance pays off p752

At long last, I've published the final part of my PhD research. Now what?

Chris Rowan

doi:10.1038/nj7163-752c


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Futures

BYOB FAQ p754

It's all you've ever wanted.

Terry Bisson

doi:10.1038/449754a


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