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Nature 449, xiii (11 October 2007) | doi:10.1038/7163xiiib; Published online 10 October 2007
Abstractions
Genetic mutation is central to evolution, but mutations that improve one aspect of a protein's function can compromise another. Until recently, gene duplication was thought to lead to the development of genes with novel functions, as one copy of the gene would be free to evolve while the other performed its original function.
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