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Organic chemistry

Zippier synthesis in water

Complex toxin molecules are the ultimate challenge for organic chemists — even successful syntheses often involve an impractical number of steps. A biologically inspired reaction might simplify things.

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Figure 1: Crimson tide.

B. BACHMAN/SPL

Figure 2: Synthetic routes to marine toxins.

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Inoue, M. Zippier synthesis in water. Nature 449, 667–669 (2007). https://doi.org/10.1038/449667a

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