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From the following article:

A histone H3 lysine 27 demethylase regulates animal posterior development

Fei Lan, Peter E. Bayliss, John L. Rinn, Johnathan R. Whetstine, Jordon K. Wang, Shuzhen Chen, Shigeki Iwase, Roman Alpatov, Irina Issaeva, Eli Canaani, Thomas M. Roberts, Howard Y. Chang & Yang Shi

Nature 449, 689-694(11 October 2007)

doi:10.1038/nature06192

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Histone demethylation mediated by UTX.

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Figure 2

UTX regulates H3K27me3 at the HOXD gene locus

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Figure 3

UTX binds near HOX gene start sites to facilitate H3K27 demethylation and gene activation.

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Figure 4

Inhibition of zebrafish Utx1 results in improper development of the posterior trunk.

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