Table of contents

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Making the paper: Leslie Vosshall and Hiroaki Matsunami pxiii

Response to the scent of a man is genetically determined.

doi:10.1038/7161xiiia


Abstractions pxiii

doi:10.1038/7161xiiib


From the blogosphere pxiii

doi:10.1038/7161xiiic


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Research Highlights

Research highlights p380

doi:10.1038/449380a


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Journal Club

Journal club p381

doi:10.1038/449381a


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Column

Party of One

Passing the test p391

What role should the federal government have in pre-college science education? David Goldston looks at why the US Congress is acting now to help define that.

David Goldston

doi:10.1038/449391a


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Business

Copycat consolidation p393

As more blockbuster drugs come off patent, generic drugmakers face a changing landscape. Meredith Wadman looks at their strategies for survival.

Meredith Wadman

doi:10.1038/449393a


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News Features

The theatre: Bringing the past to life p395

Can a stage spectacular based on a TV documentary bring science to life and please the punters too? Brendan Maher joins a palaeontologist to watch the dinosaurs walk.

Brendan Maher

doi:10.1038/449395a


Environment: Riding on the roof of the world p398

China's railway to Tibet is an engineering marvel or an environmental menace — or perhaps both. Jane Qiu takes a ride to find out.

Jane Qiu

doi:10.1038/449398a


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Correspondence

Ocean pipes could help the Earth to cure itself p403

James E. Lovelock & Chris G. Rapley

doi:10.1038/449403a


H-index: however ranked, citations need context p403

Michael C. Wendl

doi:10.1038/449403b


H-index: age and sex make it unreliable p403

Clint D. Kelly & Michael D. Jennions

doi:10.1038/449403c


Conservationists could slip up in oil-palm enterprise p403

Reuben Clements & Mary Rose C. Posa

doi:10.1038/449403d


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Books and Arts

Research funding in the twenty-first century p405

Are universities and market forces compatible?

doi:10.1038/449405a


Atlas on our shoulders p406

doi:10.1038/449406a


Ups and downs of a senator scientist p406

doi:10.1038/449406b


Oceanography fathomed p407

doi:10.1038/449407a


Exhibition: The invisible continent p408

Emiliano Feresin

doi:10.1038/449408a


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News and Views

環境科学: 森林と洪水

Environmental science: Forests and floods p409

One strategy for reducing catastrophic floods invokes protecting or regenerating forests that lie upstream of a threatened region. Support for this approach comes from a global-scale analysis of flood risk.

William F. Laurance

doi:10.1038/449409a


免疫学: 変えられた運命

Immunology: Changed destiny p410

For practical and ethical reasons, researchers are on the lookout for ways to reprogramme one mature cell type into another. In one case, this might be as easy as switching off a single gene.

Huafeng Xie & Stuart H. Orkin

doi:10.1038/449410a


核物理学: 消えない魔法トリック

Nuclear physics: A non-disappearing magic trick p411

Well-established models of nuclei describe properties such as shells and magic numbers. But how do these predictions stand up to scrutiny for exotic, unstable nuclei? Pretty well, according to the latest study.

Ragnar Bengtsson & Peter Möller

doi:10.1038/449411a


進化生物学: 歯列の発生と進化

Evolutionary biology: Development with a bite p413

Predictions drawn from experiments on the growth of molar teeth in mice, and applied to a wide range of related species, provide a remarkable connection between developmental and evolutionary biology.

P. David Polly

doi:10.1038/449413a


50 & 100 Years Ago p414

doi:10.1038/449414a


量子物理学: 光子バスを使うキュービット

Quantum physics: Qubits ride the photon bus p415

Quantum mechanics using whole electrical circuits might seem a far-fetched idea. But make the circuits superconducting, and they can be used to send and collect single photons, rather like atoms do — only better.

Antti O. Niskanen & Yasunobu Nakamura

doi:10.1038/449415a


ゲノミクス: ブドウゲノムの解読

Genomics: Vine work p417

Charles Wenz

doi:10.1038/449417a


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Review

樹状細胞の医学的側面

Taking dendritic cells into medicine p419

Ralph M. Steinman & Jacques Banchereau

doi:10.1038/nature06175


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Articles

発生から哺乳類の歯の進化パターンを予測する

Predicting evolutionary patterns of mammalian teeth from development p427

Kathryn D. Kavanagh, Alistair R. Evans & Jukka Jernvall

doi:10.1038/nature06153


酵素によるDNA中のウラシル探索の際に起こる、チミンのらせん外での捕捉

Enzymatic capture of an extrahelical thymine in the search for uracil in DNA p433

Jared B. Parker, Mario A. Bianchet, Daniel J. Krosky, Joshua I. Friedman, L. Mario Amzel & James T. Stivers

doi:10.1038/nature06131


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Letters

2個の位相キュービット間のコヒーレントな量子状態の空洞共振器を介した記憶と転送

Coherent quantum state storage and transfer between two phase qubits via a resonant cavity p438

Mika A. Sillanpää, Jae I. Park & Raymond W. Simmonds

doi:10.1038/nature06124


共振器バスを介した超伝導キュービットの結合

Coupling superconducting qubits via a cavity bus p443

J. Majer, J. M. Chow, J. M. Gambetta, Jens Koch, B. R. Johnson, J. A. Schreier, L. Frunzio, D. I. Schuster, A. A. Houck, A. Wallraff, A. Blais, M. H. Devoret, S. M. Girvin & R. J. Schoelkopf

doi:10.1038/nature06184


高密度液体ナトリウムにおける電子転移と構造転移

Electronic and structural transitions in dense liquid sodium p448

Jean-Yves Raty, Eric Schwegler & Stanimir A. Bonev

doi:10.1038/nature06123


西部太平洋暖水域の水文における最終氷期極大期以降の千年スケールの変化傾向

Millennial-scale trends in west Pacific warm pool hydrology since the Last Glacial Maximum p452

Judson W. Partin, Kim M. Cobb, Jess F. Adkins, Brian Clark & Diego P. Fernandez

doi:10.1038/nature06164


上部マントル内の金属飽和状態

Metal saturation in the upper mantle p456

Arno Rohrbach, Chris Ballhaus, Ute Golla–Schindler, Peter Ulmer, Vadim S. Kamenetsky & Dmitry V. Kuzmin

doi:10.1038/nature06183


中国東部では沿岸湿地帯における火入れと冠水管理によって最古の水田栽培が可能になった

Fire and flood management of coastal swamp enabled first rice paddy cultivation in east China p459

Y. Zong, Z. Chen, J. B. Innes, C. Chen, Z. Wang & H. Wang

doi:10.1038/nature06135


ブドウのゲノム塩基配列は主要な被子植物門の祖先で六倍体化が起こったことを示唆している

The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla p463

Olivier Jaillon, Jean-Marc Aury, Benjamin Noel, Alberto Policriti, Christian Clepet, Alberto Casagrande, Nathalie Choisne, Sébastien Aubourg, Nicola Vitulo, Claire Jubin, Alessandro Vezzi, Fabrice Legeai, Philippe Hugueney, Corinne Dasilva, David Horner, Erica Mica, Delphine Jublot, Julie Poulain, Clémence Bruyère, Alain Billault, Béatrice Segurens, Michel Gouyvenoux, Edgardo Ugarte, Federica Cattonaro, Véronique Anthouard, Virginie Vico, Cristian Del Fabbro, Michaël Alaux, Gabriele Di Gaspero, Vincent Dumas, Nicoletta Felice, Sophie Paillard, Irena Juman, Marco Moroldo, Simone Scalabrin, Aurélie Canaguier, Isabelle Le Clainche, Giorgio Malacrida, Eléonore Durand, Graziano Pesole, Valérie Laucou, Philippe Chatelet, Didier Merdinoglu, Massimo Delledonne, Mario Pezzotti, Alain Lecharny, Claude Scarpelli, François Artiguenave, M. Enrico Pè, Giorgio Valle, Michele Morgante, Michel Caboche, Anne-Françoise Adam-Blondon, Jean Weissenbach, Francis Quétier & Patrick Wincker for The French–Italian Public Consortium for Grapevine Genome Characterization 

doi:10.1038/nature06148


ヒト嗅覚受容体の遺伝的差異が匂いの知覚を変化させる

Genetic variation in a human odorant receptor alters odour perception p468

Andreas Keller, Hanyi Zhuang, Qiuyi Chi, Leslie B. Vosshall & Hiroaki Matsunami

doi:10.1038/nature06162


未拘束の前駆細胞への脱分化による成熟B細胞からT細胞への転換

Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors p473

César Cobaleda, Wolfram Jochum & Meinrad Busslinger

doi:10.1038/nature06159


IgHクラススイッチや転座はロバストな非古典的末端連結経路を使用する

IgH class switching and translocations use a robust non-classical end-joining pathway p478

Catherine T. Yan, Cristian Boboila, Ellen Kris Souza, Sonia Franco, Thomas R. Hickernell, Michael Murphy, Sunil Gumaste, Mark Geyer, Ali A. Zarrin, John P. Manis, Klaus Rajewsky & Frederick W. Alt

doi:10.1038/nature06020


Rag変異から明らかになったロバストな代替的末端連結機構

Rag mutations reveal robust alternative end joining p483

Barbara Corneo, Rebecca L. Wendland, Ludovic Deriano, Xiaoping Cui, Isaac A. Klein, Serre-Yu Wong, Suzzette Arnal, Abigail J. Holub, Geoffrey R. Weller, Bette A. Pancake, Sundeep Shah, Vicky L. Brandt, Katheryn Meek & David B. Roth

doi:10.1038/nature06168


Dscamアイソフォームの特異性の構造基盤

Structural basis of Dscam isoform specificity p487

Rob Meijers, Roland Puettmann-Holgado, Georgios Skiniotis, Jin-huan Liu, Thomas Walz, Jia-huai Wang & Dietmar Schmucker

doi:10.1038/nature06147


酵母由来AMPK相同体SNF1のヘテロ三量体コアの結晶構造

Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1 p492

Gabriele A. Amodeo, Michael J. Rudolph & Liang Tong

doi:10.1038/nature06127


哺乳類AMP活性化プロテインキナーゼへのAMP結合の構造基盤

Structural basis for AMP binding to mammalian AMP-activated protein kinase p496

Bing Xiao, Richard Heath, Peter Saiu, Fiona C. Leiper, Philippe Leone, Chun Jing, Philip A. Walker, Lesley Haire, John F. Eccleston, Colin T. Davis, Stephen R. Martin, David Carling & Steven J. Gamblin

doi:10.1038/nature06161


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Naturejobs

Prospect

Prospects p501

Paul Smaglik

doi:10.1038/nj7161-501a


Region

Enter the dragon p502

Once a poor village, Shenzhen is now one of the wealthiest cities in China. David Cyranoski learns its plans for the future.

David Cyranoski

doi:10.1038/nj7161-502a


Highlights

Highlight on Ireland

doi:10.1038/nj0179


Spotlights

Spotlight on Northern Virginia and Maryland

doi:10.1038/nj0180


Spotlight on Shenzhen

doi:10.1038/nj0181


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Futures

Alloy p506

An identity crisis.

Marissa Lingen

doi:10.1038/449506a


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