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News and Views
Nature 449, 293-294 (20 September 2007) | doi:10.1038/449293a; Published online 19 September 2007
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- South Dakota State University
- Brookings, SD
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- Georgia, USA
Structural biology: Unexpected opening
Cecilia M. Canessa1
Abstract
Cell membranes contain channels that open to allow ions into cells. The structure of a sodium ion channel helps explain how it opens in response to protons, and settles a long-standing debate about its composition.
What do humans have in common with worms, flies, hydra and sea urchins? One answer is that they all have proteins known as degenerins1 that form pores in cell membranes for the passage of sodium ions.
- Cecilia M. Canessa is in the Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Email: cecilia.canessa@yale.edu
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