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Nature 449, 288-291 (20 September 2007) | doi:10.1038/449288a; Published online 19 September 2007
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Senior Analyst - SCI
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- Bengaluru 560 071 India
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- University of Southampton
- Southampton / Hampshire United Kingdom
Ageing: From stem to stern
Anne Brunet1 & Thomas A. Rando1
Abstract
Immortality is the stuff of myth and legend, but lifespan extension is the subject of serious scientific inquiry. Exploring the causes and effects of ageing in stem cells should aid this quest.
The explosion of research on stem cells has given the promise of treatments for degenerative diseases of ageing, enhancement of the repair of damaged tissues and possibly even slowing of decline-in-function that occurs with advancing age. But how stem cells are affected by the ageing process, and whether such changes are a cause or a consequence of organismal ageing, remain unclear1.
- Anne Brunet is in the Department of Genetics, and Thomas A. Rando is in the Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA.
Email: anne.brunet@stanford.edu
Email: rando@stanford.edu
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