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Nature 449, 166-169 (13 September 2007) | doi:10.1038/449166a; Published online 12 September 2007

Neglected Diseases Mission possible

Andrew L. Hopkins1, Michael J. Witty2 & Solomon Nwaka3

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One billion people worldwide suffer from tropical diseases. Andrew L. Hopkins, Michael J. Witty and Solomon Nwaka explain how drug-discovery networks might be scaled up to address the lack of treatments cost-effectively.

New drugs are urgently needed for neglected tropical diseases and tuberculosis. Although one person in six suffers from such diseases, the few drugs available are not widely used, owing to problems with safety, administration, cost and — increasingly — resistance of the infectious agents1.