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News and Views
Nature 449, 149-151 (13 September 2007) | doi:10.1038/449149a; Published online 12 September 2007
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Chemistry: Molecular socks in a drawer
Michael D. Ward1
Abstract
Dynamic combinatorial chemistry is a deft way to identify the most stable forms in a complex mixture of interconverting compounds. Even more cunningly, it can also be used to sort related molecules by crystallization.
As chemists seek to produce increasingly complex molecules and molecular assemblies, it has become evident that complexity often comes at a price — the many different reaction pathways can generate unwanted mixtures and side products. This is particularly true when the reaction pathways and products are similar energetically.
- Michael D. Ward is at the Molecular Design Institute, Department of Chemistry, New York University, 100 Washington Square East, New York, New York 10003-6688, USA.
Email: mdw3@nyu.edu
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