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Nature 449, 35-37 (6 September 2007) | doi:10.1038/449035a; Published online 5 September 2007

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Cell biology: Taxi service for lipids

Anthony H. Futerman1

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With its role in intracellular protein transport already known, the FAPP2 protein has now also been implicated in lipid transfer and synthesis. What is more, these two FAPP2-mediated events seem to be linked.

The cellular pathways mediating the secretion of proteins such as hormones and antibodies were first described by George Palade and colleagues1 in the 1960s. Many gaps have been filled since the heyday of their work, but the basic principles remain as originally described.

  1. Anthony H. Futerman is in the Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel.
    Email: tony.futerman@weizmann.ac.il

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